What are the factors that affect the quality of the finished granule

1. Moisture: 11%-13% of raw materials, 15%-17% after quenching and tempering, generally 1% corresponds to 11;

2. Starch: the surface of raw starch is rough, the granulation resistance is large, and the bonding performance is poor; The gelatinized starch has good adhesion properties and particles.

3. The starch of barley and wheat is better than that of cornstarch. If the grain is matured before conditioning (e.g. corn is dried), the grain yield decreases. Therefore, it is better not to choose drying when purchasing raw materials;

4. Protein: When the protein content in the formula is high, it is easier to granulate, and the particle quality is also better, because the plasticity and viscosity of the protein increase after heating, so that the granulation yield is improved. When the protein content is too high, the granulation effect decreases, and the conditioning temperature is low due to the serious reduction of the ability to absorb steam. In addition, when the non-protein nitrogen (such as urea, etc.) is high, the granulation yield is reduced;

5. Fat: an appropriate amount of fat, low friction resistance, small wear of the ring die, low energy consumption, and particles, which are generally controlled within 3% before granulation; The fat content is too high, the quality of the particles decreases, and the particles are soft and brittle. When adding a high dose of grease, it is advisable to add 30% of the full amount at the mixer and 70% of the full amount after the granulator.

6. Crude fiber: the appropriate crude fiber content (3% 5%) is conducive to the bonding of granules, reducing the pulverization rate of granules, and improving the granulation yield. However, when the crude fiber content exceeds 10%, due to the poor adhesion of the fiber itself, the binding force between feed particles decreases, and at the same time, it also affects the ability of feed to absorb steam, so that the hardness, forming rate and yield of feed particles are reduced, and the wear and tear of equipment is seriously increased.

The quality of the product is not only affected by itself, but also by the incentive and constraints of the external environment; It is not only affected by material factors, but also by policy, social, natural, economic and other factors.

Hope it helps!

First, the quality requirements of granules.

The granules should be dry, the particle size should be uniform, the color should be consistent, with a certain hardness, and there should be no moisture absorption, softening, agglomeration, deliquescent and other phenomena. When the soluble granules are taken with hot water, the application part is dissolved, and slight turbidity is allowed; Suspension granules should be medically educatedThe net collection and finishing can be suspended evenly, and there must be no foreign objects such as scorched chips; Effervescent granules should produce carbon dioxide gas immediately after adding water and be efferving. Particle moisture, device differences and hygienic standards should all comply with the relevant regulations.

Sakura Big. Second, the quality inspection of granules.

1.The granularity must not be exceeded.

2.The moisture granules shall not exceed; Lumpy granules should not be exceeded.

3.Solubility.

4.Difference in loading volume.

5.Hygienic standards.

Example 1: 1250g of powdered sugar and 250g of sodium hydrogen hydrogen acid are taken from effervescent granules of mountain slag, mixed and granulated; Spray the spine smile into an appropriate amount of flavor, and then add citric acid to mix evenly.

Example 2: 90g of lactose and magnesium stearate were added to the dry product of Gegen decoction, mixed well, and then pressed large tablets (tablet weight 2g, diameter cm), and the pre-pressed tablets were crushed in a swinging granule machine.

Answer]: B, C

The test center of this question is the quality inspection of granules. Unless otherwise specified, the moisture content of the granules shall not exceed, and the sum of the particles and powders that cannot pass through the No. 1 sieve and the No. 5 sieve that can pass through the scattered bend shall not be over-filled by more than 15% in the particle size balance inspection. So choose BC.

Answer]: C granules can be divided into soluble granules, suspension granules, effervescent trace granules, enteric-coated granules, sustained-release granules and controlled-release granules, etc., for oral use.

1.Active ingredient content.

2.Suspension rate (for dispersible granules WG, soluble granules SG does not have this item) 3Wettability (for dispersible granules WG, soluble granules SG does not have this item) 4

Disintegration (for dispersible granules WG, soluble granules SG do not have this item) 5Moisture content.

6.Wet sieve.

7.Blistering.

8.Heat storage stability.

9.Cold storage stability.

10.Appearance.

11. ph

The above serial numbers are for statistical purposes only, not for importance rankings.