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The recommended starting dose of Lipitor is 10 mg once daily. The dose range is 10-80 mg per day. Lipitor can be taken orally as a single dose at any time of the day, with or without food.
Lipitor, a white, oval, coated atorvastatin calcium salt tablet, is a synthetic, selective, competitive HMG-Coa reductase inhibitor (statin). Lipitor reduces plasma cholesterol and lipoprotein levels by inhibiting the biosynthesis of HMG-Coa reductase and cholesterol in the liver, and increases LDL uptake and catabolism by increasing the number of LDL receptors on the surface of hepatocytes; Lipitor also reduces LDL generation and particle count. Lipitor reduces blood paddle total cholesterol (Total-C), low-density lipoprotein cholesterol (LDL-C), and apolipoprotein B (APO-B) levels in homozygous and heterozygous patients with familial hypercholesterolemia, nonfamilial hypercholesterolemia, and mixed hyperlipidemia.
Lipitor also reduces the levels of VLDL-C and TG, and can increase the levels of plasma HDL-C and apolipoprotein A-1 to varying degrees. As a dietary framework, Lipitor is used to reduce total cholestatic LDL-C, apolipoprotein B, and triglycerides in patients with primary hypercholesterolemia (heterozygous familial or non-familial) and mixed hyperlipidemia (Fredrickson 1LA and 11B). Lipitor is used in combination with other lipid-lowering patients (eg, LDL-C plasmapheresis or when no other means are available** in homozygous patients with familial hypercholesterolemia.
Adverse effects: Lipitor is generally well tolerated, but adverse effects are mostly mild and transient. The most common adverse events thought to be associated with atorvastatin were constipation, bloating, dyspepsia, and abdominal pain.
Precautions: Lipitor is contraindicated in patients with active liver disease or unexplained persistently elevated aminotransferases, hypersensitivity to any component of the drug. Renal insufficiency:
Kidney disease does not affect the plasma concentration of atorvastatin and its effect on reducing LDL-C, and in patients with renal insufficiency, it is not necessary to adjust the dose of the drug. Abnormal liver function: It is recommended to perform liver function tests before ** start, 6 weeks after start, 12 weeks after start, or after increasing the dose of the drug, and regularly in the future (eg:
Half a year) to measure liver function. If alanine aminotransferase or aspartate aminotransferase persistently exceeds 3 times the upper limit of normal, dose reduction or discontinuation of the drug is recommended. Use with caution in patients who drink heavily or have a history of liver disease.
Skeletal muscles: Patients with unexplained myalgia, muscle tenderness, or weakness, especially if accompanied by malaise or fever, should be reported immediately. If creatine phosphokinase levels are markedly elevated or if myopathy is diagnosed or suspected, the drug should be discontinued.
Hemodialysis: hemodialysis does not significantly increase atorvastatin clearance. Pregnancy and lactation:
For pregnant and lactating women, HMG-CoA reductase inhibitors are contraindicated. The safety of its use in pregnant women has not been established. Storage:
Store at room temperature 20-25 °C.
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You can consult your doctor according to the actual situation.
Patients should be controlled by a standard low-cholesterol diet before starting this product**, and a reasonable diet should be maintained throughout the ** period. Dose should be individualized based on baseline LDL cholesterol levels, goals, and patient's efficacy. A common starting dose of 10 mg once a day is commonly used.
The dose adjustment interval should be 4 weeks or more. The maximum dose of this product is 80mg once a day. The daily dose of atorvastatin can be taken at any time of the day and is not affected by meals.
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Lipitor (atorvastatin calcium tablets) is a statin lipid-modifying drug, which is an HMG-Coa reductase inhibitor. It is inactive, and the hydrolysate after oral absorption competitively inhibits the rate-limiting enzyme oxymethaglutaryl-CoA reductase in the process of cholesterol synthesis in vivo, so that the synthesis of cholesterol is reduced, and the synthesis of low-density lipoprotein receptors is increased, and the main site of action is in the liver, resulting in a decrease in blood cholesterol and low-density lipoprotein cholesterol levels, a moderate decrease in serum triglyceride levels and an increase in blood high-density lipoprotein levels. This has an effect on the prevention and treatment of atherosclerosis and coronary heart disease.
It is recommended to measure liver function at **before, 6 and 12 weeks after **start, or at an increased dose, and in the long term**, at regular intervals (eg, annually). Changes in liver enzymes usually occur during the first trimester of atorvastatin calcium, and patients with elevated liver enzymes should be adjusted until recovery. When ALT or AST is elevated more than 3 times normal, it is recommended to reduce the dose or discontinue the drug.
Patients who drink a lot of alcohol or have a history of liver disease should be cautious about atorvastatin calcium.
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Disease analysis: Hello, Lipitor is a commonly used drug for hyperlipidemia, coronary heart disease, stroke, etc., which generally requires long-term medication, but long-term medication may aggravate liver and kidney function Guidance: It is recommended that if the symptoms are reduced, the dose can be reduced, and it is best to stop the drug slowly.
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It depends on how high your blood lipids are. If you stop taking the medicine after eating, you don't need to eat it if the blood lipid value can be normal. Otherwise, you have to eat.
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It's a prescription drug. How long to take it is necessary to ask the prescriber doctor.
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4 After 6 weeks, according to the test results, if it is normal, stop and stick to a low-fat diet. Yes, there will always be ***.
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It depends on how high your blood lipids are. If you stop taking the medicine after eating, you don't need to eat it if the blood lipid value can be normal. Otherwise, you have to eat.
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It's a prescription drug. How long to take it is necessary to ask the prescriber doctor.
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Lipitor is a drug used for high cholesterol and heart disease, which is widely welcomed by people, but there are also some Lipitor products, I believe you will know after reading the following description.
1.First, Lipitor has the most common adverse reactions of gastrointestinal discomfort, and others include headache, rash, dizziness, blurred vision and taste cracking sensation.
2.Second, imitation and taking Lipitor are rare, myositis, myalgia, rhabdomyolysis, manifested as muscle pain, fatigue, fever, accompanied by elevated blood creatine phosphokinase, myoglobinuria, etc., rhabdomyolytic hydrolysis can lead to renal failure, but it is rare. The combination of this product with immunosuppressants, folic acid derivatives, niacin, gefibrozil, erythromycin, etc., can increase the risk of myopathy.
3.Thirdly, taking Lipitor can cause a reversible increase in blood aminotransferase, so it is necessary to monitor liver function, and rare adverse reactions include impotence and insomnia.
Precautions. Although Lipitor has a great effect, not everyone can take it, so you must take it according to your physical condition to avoid harm to your body.
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There are no special measures for the overdose of this product. In the event of an overdose, patients should take symptomatic and supportive measures as needed. Due to the extensive binding of Lipitor to plasma proteins, hemodialysis does not significantly increase Lipitor clearance.
Not suitable for long-term use. Treating the symptoms but not the root cause, inhibiting gastric acid drugs, there is no benefit after a long time.