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I believe you have also passed the clinical significance of CA125 representatives:
Clinical significance of CA125.
Other influencing factors: pelvic inflammatory disease, endometriosis, menstruation, ovarian cysts, uterine fibroids, chronic hepatitis, pancreatitis, cholecystitis, pneumonia, etc. will be elevated. Xiao Jiancun, Department of Gastroenterology, Beijing Jingmei Group General Hospital.
CA125 is the preferred marker for ovarian and endometrial cancer, and if a positive limit of 65 U mL is used, the accuracy rate of stage - cancer can reach 100%. CA125 is by far the most important indicator for early diagnosis, efficacy observation, prognostic judgment, surveillance** and metastasis of ovarian cancer. The combination of CA125 measurement and pelvic examination increases the specificity of the test.
The coincidence rate for the diagnosis of fallopian tube, endometrial cancer, cervical cancer, breast cancer and mesothelial cell carcinoma is also high, and the positive rate of benign lesions is only 2%. Elevated levels of CA125 are a signal of female germline tumors**.
Dynamic observation of serum CA125 concentration is helpful for the prognosis evaluation and control of ovarian cancer, after **, the CA125 content can be significantly reduced, if it cannot return to the normal range, the possibility of residual tumor should be considered. Serum Ca125 concentrations greater than 35 mL in 95 patients with residual tumors. In the case of ovarian cancer**, CA125 can be elevated several months before clinical diagnosis, and the serum CA125 in patients with metastasis of ovarian cancer is significantly higher than the normal reference value.
Elevated CA125 can also be seen in ascites due to various malignancies. Elevated CA125 can also be seen in a variety of ** benign diseases, such as ovarian cysts, endometrial disease, cervicitis and uterine fibroids, gastrointestinal cancer, liver cirrhosis, hepatitis, etc.
The above is the encyclopedia's explanation of the clinical significance of CA125, your CA125 value is still quite high, it can only be said that the possibility of malignancy is relatively large, not 100% certain, you look at the most two lines above me, "CA125 elevation can also be seen in a variety of ** benign diseases, such as ovarian cysts, endometrosis, cervicitis and uterine fibroids, gastrointestinal cancer, liver cirrhosis, hepatitis", there are also some common diseases that will also lead to this CA125 elevation.
I recommend that you go to the hospital where you are treated and have a pathological biopsy, which is a golden indicator.
Hope it helps.
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Don't think too much. Actual.
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A mere one doesn't mean anything.
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The 1ca125 test is a tumor marker, carbohydrate antigen, and is also a specific marker for ovarian cancer, which can be used for:
1.early diagnosis and detection of tumors;
2.Sites and tissues suggestive of tumorigenesis**;
3.differential diagnosis of tumors;
4.Observation of the efficacy and prognosis of the tumor**;
5.Monitoring tumors** plays an important role.
1.normal serum < 35 g l;
2.Menopausal women < 25 g l.
2Ca125 is not present in normal ovarian tissue, nor is it present in mucinous ovarian tumors, so CA125 test results are not high or high.
The CA125 test results of patients with epithelial ovarian tumors (serous tumors) are usually 80% high, but the high CA125 test results may also be caused by other reasons, not necessarily due to ovarian cysts, but also may be liver cirrhosis, chronic pancreatitis, hepatitis, endometriosis, uterine fibroids, uterine myadenosis, pelvic inflammation, etc., it is recommended to do a detailed general examination to determine the cause.
3. If it is determined that the CA125 is high due to ovarian cysts, then the indication for surgery has been met and surgery is required.
1.In general, ovarian cysts persist or enlarge, and the diameter of the cyst persists more than 5 cm before and after menstruation;
2.Poor acoustic transmission or uneven echo of ultrasound cysts, such as ovarian chocolate cysts and teratomas;
3.Blood Ca125 is higher than normal;
4.Affecting reproductive endocrine, such as ovulation, blood work, etc., laparoscopic surgical exploration can be considered.
Ovarian cysts during puberty, postmenopause, contraceptive pills, or after hysterectomy should be paid special attention.
Laparoscopic ovarian cyst surgery, compared with the traditional laparotomy, has the advantages of small wound, less impact on the abdominal environment, less bleeding and fast recovery.
4. If CA125 is high after ovarian cyst surgery, it means that the ovarian cyst will be **, and the concentration of ovarian tumor will increase a few months earlier than that of the clinic.
Therefore, for patients with post-ovarian tumor resection, CA125 should be measured on the 6th postoperative day, and then followed by its half-life, and if CA125 does not return to the normal range, the possibility of residual tumor should be considered.
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Hello, CA125 and CA199 are substances that can be used to determine whether they are tumors. Because you have already seen a lump on ultrasound, but you don't know if it's a cyst or a tumor, you do these two tests.
If the CA199 data is too high from your data, the lump can be diagnosed as a tumor, but its borders are clear and the cyst wall is intact, indicating that it is benign.
You can choose to use laparoscopic surgery, which only involves cutting three 1 cm incisions in the abdomen, and one of them is in the belly button, which is not easy to detect.
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Hello, from your auxiliary examination report, the possibility of benign is relatively large, if you don't want to undergo surgery, you can observe first, and then recheck the pelvic ultrasound after three months, if the tumor increases significantly or the tumor marker value rises significantly, or there are symptoms, you have to operate.
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It is slightly high, not a malignant tumor, it may be caused by poor rest or a cold, and it will be re-examined when the physical condition is good.
Song Luyin, Guangdong Provincial Maternal and Child Health Hospital.
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Laparoscopic surgery is recommended for ovarian tumors, but the gastrointestinal symptoms you mentioned have nothing to do with ovarian tumors, and I am afraid that you still need to see a Chinese medicine doctor or consult a gastroenterologist. If you really don't want to do it, you must have a repeat** ultrasound every year, once it is significantly enlarged, or the whole is more than 4cm, or the tumor has a blood flow signal, you must have surgery as soon as possible. In addition, it is more likely that your ovarian tumor is teratoma, and the biggest problem with teratoma is the sudden reversal of the stalk, once it occurs, if the doctor is not in time, it can lead to the need to remove the ovary on the affected side.
So you'd better be careful. This surgery is not too difficult. Normally, we will be discharged from the hospital within three days after surgery.
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CA125 ovarian cancer tumor antigen results were:
Clinical significance of CA125 ovarian cancer tumor antigen: cancer antigen 125 is mainly used to assist in the diagnosis of malignant serous ovarian cancer and ovarian epithelial carcinoma, and it is also a good indicator for efficacy assessment and judgment of whether there is or not. Heightened:
Seen in ovarian cancer, breast cancer, pancreatic cancer, gastric cancer, etc.; Non-malignant tumors such as endometriosis, pelvic inflammatory disease, ovarian cysts, etc. are also increased; In addition, elevated cancer antigen 125 can be seen in benign and malignant pleural effusion and ascites, and there is also a possibility of elevation of cancer antigen 125 in the first 3 months of pregnancy.
CA-125 is not a specific ovarian cancer antigen, and a high level does not mean ovarian cancer, and has no diagnostic significance.
Just a hint that you need to consider the above possibilities.
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