What are the characteristics of ALS? What are the symptoms of ALS?

ALS is a common name for a group of motor neuron diseases that do not affect the intellect, memory and sensation of patients because the sensory nerves are not disturbed. Lu Yuanfang, the first pregnant "ALS person" in China, went to Beijing from her hometown in Gansu to give birth to a baby boy and successfully gave birth to a baby boy. The ** is the invasion of motor nerve cells in the brain, brainstem and spinal cord of the patient, and the patient's muscles gradually atrophy and weakness, so that the paralysis, and the body seems to be gradually frozen, so it is commonly known as "ALS".

Like the well-known master of physics and scientific giant Stephen Hawking, he is a "gradual freezing person". Clinical signs:

1.Onset of symptoms: In the early stages of the disease, you may not be able to hold chopsticks in your hands, or you may fall when you walk for no reason; Some begin with a hoarse voice without any obvious symptoms.

Neuromuscular physicians should do the necessary tests such as electromyography, nerve conduction velocity, and magnetic resonance imaging to confirm the diagnosis.

2.Difficult period at work: Obvious limb weakness or even atrophy, life can still take care of themselves, but obstacles have appeared in the workplace.

At this time, it is necessary to take moderate rest to avoid aggravation of the disease. Necessary rehabilitation is provided by a rehabilitation physician and a social worker assists in psychological adjustment and social resources.

3.Difficult life: In the middle stage of the disease, the hands or feet, or the hands and feet have serious impairment at the same time, and they are unable to take care of themselves, and may not be able to walk, dress, hold chopsticks, and slurred speech.

4.Dysphagia stage: In the middle and late stages, the limbs are almost completely weak, the speech is severely impaired, it is easy to choke when eating, and some need to be fed, otherwise it is easy to lead to aspiration pneumonia.

5.Dyspnea: Respiratory muscles have been affected, breathing is difficult, patients may be bedridden, need to use a respirator, some will be admitted to a respiratory center** or choose home care, and some will be served by a hospice team. Depending on the severity of the lesion, two types of symptoms can be seen:

1. Symptoms of upper neurons include: deterioration of fineness, muscle weakness, spasticity, pathological reflexes, curvature spasm and pseudobulbar signs.

2. Symptoms of lower neurons include: muscle weakness, muscle atrophy, decreased reflexes, muscle tremors, and cramps. At first, it may be just a general symptom such as peripheral limb weakness, muscle twitching, and easy fatigue, but gradually it will progress to muscle atrophy, difficulty swallowing, and finally respiratory failure.

Depending on the symptoms at the beginning, it can be divided into two modes of disease development:

2. Start with bulbar muscle paralysis: when the limbs are still moving well, the symptoms of difficulty swallowing and speaking have appeared, and then soon progress to respiratory failure.

ALS people are people with motor neurone disease . This is a progressive neurodegenerative disease that may occur in the central nervous system or in the peripheral nervous system, and there are many types depending on the location of the lesion, the pathogenesis and symptoms, the most common of which is amyotrophic lateral sclerosis. This disease is more common in middle-aged people in their 40s and 50s, after the disease will have movement disorders, and within two to five years, from inconvenience, difficulty swallowing, slurred speech, progression to quadriplegia, loss of speech and swallowing ability, and finally affect cardiopulmonary function, must rely on nasogastric tubes and respirators to maintain life.

Typical symptoms. Amyotrophic lateral sclerosis.

The most common first symptom is clumsiness and weakness of one or both fingers, followed by atrophy of the small finger muscles in the segments, which gradually progress to the muscles of the forearm, upper arm, and shoulder. As the course of the disease prolongs, muscle weakness and atrophy extend to the trunk and neck, and eventually to the facial and laryngeal muscles. In a few cases, muscle atrophy and weakness begin in the lower extremities or trunk.

Fasciculations are often evident in the affected area.

Progressive amyotrophy.

The most common first symptom is atrophy and weakness of the small muscles in one or both hands, which gradually affects the muscles of the forearm, upper arm, and shoulder. Affected muscles are markedly atrophied, muscle tone is reduced, and muscle tremors may be seen.

Progressive bulbar palsy.

The main manifestations are progressive slurred articulation, dysphagia, choking on water, and chewing weakness. The tongue muscles are obviously atrophied, and there are fasciculations, and the lip muscles and throat muscles are atrophied. This type of disease progresses rapidly, and most of them die within 1 to 2 years due to respiratory muscle paralysis or lung infection.

Primary lateral sclerosis.

The most common presenting symptoms are symmetrical stiffness and fatigue in both lower extremities, and walking with a scissor gait. Progresses slowly and gradually affects both upper extremities. There is usually no muscle atrophy and fasciculations, and no sensory deficits. This type progresses slowly and can survive for a long time.

Other symptoms. A small percentage of patients with motor neuron disease have manifestations outside the motor system, such as dementia, paresthesia, and urinary and urinary dysfunction, and a small number of patients have extraocular muscle movement disorders.

The diagnosis of ALS requires a comprehensive judgment by a professional physician based on clinical manifestations and examination results, and cannot be diagnosed by oneself.

ALS is a chronic progressive disease in which upper and lower motor neuron lesions predominate.

The main clinical manifestations of ALS are muscle weakness, muscle atrophy, bulbar palsy, and pyramidal tract signs, and sensory and sphincter function are generally not affected. The first symptom of the disease is usually clumsiness and weakness of one or both fingers, followed by atrophy of small muscles. If there is no sensory impairment after middle age, such as chronic and progressive muscle weakness, muscle atrophy, bulbar palsy, pyramidal tract signs, etc., and there is no sensory impairment, the possibility of motor neuron disease should be considered.

There may be many clinical reasons for the above symptoms, so these symptoms alone cannot be determined to be ALS. On the one hand, these symptoms continue to worsen and the response to ** is not obvious, on the other hand, relevant examinations should be done, including spinal magnetic resonance, electromyography examination, in addition, nerve conduction velocity testing, as well as serum special antibody testing and cerebrospinal fluid examination, and if necessary, muscle biopsy. Based on the results of these examinations, a final judgment can be made.

ALS people are mainly muscle atrophy, under normal circumstances, the early symptoms are relatively mild, can be only some, that is, fatigue, weakness, or muscle soreness, easy fatigue, such symptoms, with the development of the disease, there may be muscle atrophy of the whole body, and difficulty swallowing, the most serious may appear respiratory failure and death.

ALS is one of the types of motor neuron disease, and the main types of motor neuron disease include amyotrophic lateral sclerosis, progressive amyotrophy, progressive bulbar palsy, and primary lateral sclerosis. Among them, amyotrophic lateral sclerosis, also known as ALS, shows muscle weakness and muscle atrophy because the upper motor neurons and lower motor neurons are damaged, and gradually develops, which is manifested as muscle stiffness, as if it is frozen, so. More.

ALS, also known medically as amyotrophic lateral sclerosis. It is a chronic, progressive disease. ALS will affect upper motor neurons, such as the brain, and will also have a certain impact on lower motor neurons, and the patient's trunk, limbs, head and face muscles will also be affected.

At the same time, the disease mainly occurs in the middle-aged and elderly groups. And at present, the disease is not **.

1. Symptoms that will occur after suffering from ALS.

1. The patient's motor neuron will be damaged, so the patient's motor ability will be impaired to a certain extent.

2. At the same time, paralysis will occur.

3. It is also difficult to swallow.

4. And some patients will also have no sensory impairment.

Second, the best method for ALS.

1. Patients can use medications**. Like citicoline, antan, basic fibroblast growth factor, etc. However, when using drugs, patients should pay attention to the specific use of drugs to follow the doctor's advice and not to use drugs without authorization.

2. At the same time, patients can also use dietary therapy as an aid.

3. Nursing care for ALS.

1. Pay attention to the patient's psychological state, maintain a positive attitude, and actively cooperate with the patient.

2. At the same time, patients should also have a certain amount of exercise, but pay attention to the combination of work and rest, because a small amount of exercise will enhance physical fitness and avoid the aggravation of the disease.

Early symptoms are mild and can be easily confused with other diseases. Patients may only feel some symptoms such as weakness, flesh jumping, and fatigue easily, and gradually progress to generalized muscle atrophy and difficulty swallowing. Respiratory failure develops.

According to the clinical symptoms, it can be roughly divided into two types:

1.Limb-onset type.

Symptoms begin with progressive atrophy and weakness of the muscles in the limbs, and finally respiratory failure.

2.Bulbar onset.

Difficulty swallowing and speaking begins with early progression, and respiratory failure soon progresses.

The symptoms of ALS are mainly manifested as starting from the limbs, the muscles of the limbs begin to atrophy to a certain part, and become weak, and then extend to other parts, and finally produce respiratory failure, the common is that 60% to 70% of patients first start from the small muscle atrophy of the hand.

ALS is more common in men aged 40-50 years old, and it is a rare disease that can cause muscle weakness, muscle atrophy and pyramidal tract signs. If the patient has a long onset of the disease, it will develop dementia and paresthesias, and even affect the movement of the limbs. Everyone should beware of the occurrence of ALS and popularize the symptoms of the disease, so what are the symptoms of ALS?

1. Muscle weakness and muscle atrophy.

Muscle weakness and muscle atrophy are the most obvious symptoms of ALS, which can lead to clumsiness and weakness in one or both finger movements, and severe atrophy of the small muscles of the hand after aggravation, especially the damage to the thenar muscles and muscles. With the prolongation of the onset time, the patient's hands appear in the shape of eagle claws, and will gradually extend to the forearm, upper arm and other parts, and then aggravate the patient's condition.

2. Fasciculation.

The affected parts will produce obvious symptoms of fasciculation, and will also affect the health of the palate, pharynx, larynx and other parts, all of which will produce different degrees of muscle atrophy and weakness, resulting in the patient's arthria, accompanied by dysphagia and decreased masticatory function. Due to the damage of the bilateral corticobulbar tracts, it is easy to produce pseudobulbar paralysis symptoms, and severe cases should seek medical attention immediately.

3. Pyramidal tract sign.

If ALS patients have a longer onset time, both upper limbs will also be affected, resulting in muscle contraction and hypotonia, but tendon reflexes are severely hyperactive. In general, patients do not have objective sensory disorders, but are prone to subjective sensory symptoms, such as numbness.

4. Other performances.

Only a few patients will have dementia or paresthesias, and in severe cases, their bladder and rectal function will be impaired to varying degrees, and sometimes memory will be affected, which will bring trouble to life and work.

The above four points are the common manifestations of ALS, the disease is particularly common, and the harm is more serious, after the onset of the disease can not delay the time of treatment, early medication can temporarily alleviate the patient's condition. However, for patients with severe limb damage, surgical treatment should be given, and corresponding training should be strengthened. In addition, adjust your mentality and arrange your diet reasonably during the onset of the disease.

ALS people are mainly muscle atrophy, under normal circumstances, the early symptoms are relatively mild, can be only some, that is, fatigue, weakness, or muscle soreness, easy fatigue, such symptoms, with the development of the disease, there may be muscle atrophy of the whole body, and difficulty swallowing, the most serious may appear respiratory failure and death.

Generally referred to as amyotrophic lateral sclerosis, also known as motor neuron disease, is the gradual weakness and atrophy of the muscles including the bulb, limbs, drainage, chest and abdomen after the injury of upper motor neurons and lower motor neurons.

ALS people are people with motor neuron disease. Motor neuron disease (MND) is a common neurodegenerative disease that primarily damages the upper and/or lower motor neurons of the cerebral cortex, brainstem, and spinal cord, resulting in motor function involvement.

ALS is actually a common name for amyotrophic lateral sclerosis (ALS), a neurological disorder.

Because of the damage of motor neurons, the patient gradually appears and worsens muscle weakness, muscle atrophy, difficulty swallowing, choking on water, slurred speech and other symptoms.

ALS is a rare disease, affecting about 4 in 6 people per 100,000 people.

And until now, als's ** is still unclear.

All we know is that the neurons that innervate muscle movement are slowly denatured for reasons unknown to humans, and as these motor neurons slowly die and disappear, the muscles slowly lose their ability to move, and atrophy little by little, until they die.

What's even more frightening is that the vast majority of patients with ALS develop it later in adulthood because it is an acquired disease.

That means that the patient is slowly losing his ability to exercise and take care of himself after feeling all the sports life as a healthy person.

At first, it may just be that you stumble upon your fingers that aren't so flexible;

Then, you find yourself unable to hold a teacup in one hand;

Then, there will be a situation where there is no way to comb your hair;

Later, the chic action of crossing his hands behind his head with his hands extremely relaxed gradually drifted away, and he could no longer complete ......

Soon after the appearance of various movement disorders in the upper limbs, the lower limbs are inevitably affected.

From being able to ride around Qinghai Lake on a bicycle to being difficult to climb two floors, for an ALS patient, it may only be a dozen months away.

When muscle atrophy involves the muscles responsible for speaking, ALS sufferers slowly lose the ability to speak, and eventually can only express themselves through eye trackers.

And when the muscles that eat and breathe are affected, it means that death is near.

During this time, due to the atrophy of the respiratory muscles, the patient will always have a feeling of not being able to take a full breath of oxygen.

It was like being waterboarded at all times.

And for ALS patients, the most painful thing is not the inability to exercise and eventual death.

Instead, throughout the course of the disease, he always maintained a clear brain and a good ** sensory ability.

You touch his body, he can feel it, but he can't give you a response;

When you talk to him, he can hear it clearly, but he can't make the right expression.

His sober brain watched the muscles disappear little by little, and there was a visible beating before the muscles and innervated neurons were lost, which was actually the last struggle of the muscles.

Every moment, I can feel my body being withdrawn, deprived, and cut off, watching my familiar body and familiar feelings, like withered flowers visible to the naked eye, leaving me every second.