How pancreatitis is mainly caused

Updated on healthy 2024-06-11
2 answers
  1. Anonymous users2024-02-11

    **。Under normal conditions, pancreatic juice contains inactive pancreatic propancrat in its glandular tissue. Pancreatic juice flows into the duodenum along the pancreatic duct through the common bile duct Oddi's sphincter, and due to the presence of bile in the duodenum and the secretion of an enterokinase by the mucosa of the duodenal wall, pancreatic propancrat begins to transform into a highly active digestive enzyme.

    If the outflow tract is blocked and the excretion is not smooth, pancreatitis can be caused.

    When the sphincter of Oddi's muscle spasms or the pressure in the bile duct increases, such as stones and tumors, bile will reflux into the pancreatic duct and enter the pancreatic tissue, at this time, the lecithin contained in the bile is broken down into lysolecithin by lecithin A contained in the pancreatic juice, which can have a toxic effect on the pancreas. In biliary tract infections, bacteria can release kinases that activate pancreatic enzymes, which can also be turned into active substances that can damage and dissolve pancreatic tissue. These substances convert the trypsinogen contained in pancreatic juice into trypsin, which has strong digestion activity and penetrates into pancreatic tissue to cause self-digestion, and can also cause pancreatitis.

    Acute pancreatitis.

    It is an acute inflammation caused by pancreatic digestion of the pancreas and its surrounding tissues, which is mainly manifested as edema and necrosis of the pancreas. The causes are as follows:

    1) Biliary system diseases Bile duct inflammation, stones, parasites, edema, spasm and other lesions cause the ampulla to be obstructed, and bile refluxes into the pancreatic duct through a common channel, activating pancreatinogen, thus causing pancreatitis.

    2) Alcoholism and overeating Alcoholism and overeating make the secretion of pancreatic juice vigorous, and the drainage of the pancreatic duct is not smooth, resulting in increased pressure of pancreatic juice in the pancreaticobiliary system, resulting in high concentration of protease excretion disorders, and finally leading to the rupture of pancreatic vesicles and the onset of the disease.

    3) Injury to the stomach, biliary tract and other abdominal cavities to the pancreas, or cause pancreaticobiliary pressure to be too high.

    4) Infection Many infectious diseases can be complicated by acute pancreatitis, and the symptoms are mostly not obvious. If roundworms enter the bile duct or pancreatic duct, they can bring in bacteria, which can activate pancreatic enzymes and cause pancreatic inflammation.

    5) Hyperlipidemia and hypercalcemia Hyperlipidemia, embolization of pancreatic blood vessels causes ischemia, telangiectasia, damage to the blood vessel wall, resulting in difficulty in pancreatic juice excretion; Stones can block the pancreatic ducts, causing pancreatitis.

    2.Chronic pancreatitis.

    A disease of chronic progressive destruction of the pancreas caused by the recurrence of acute pancreatitis.

  2. Anonymous users2024-02-10

    This actually says what are the best studies of pancreatitis? The most common in China is biliary pancreatitis. Biliary pancreatitis mainly includes gallbladder stones, as well as stones of the common bile duct, which fall from the gallbladder to the bile duct, and then cause the secretion disorder of the pancreatic duct, which will cause or induce acute pancreatitis, which is the most common in China.

    In addition, with some changes in modern people's lifestyles, alcoholic and hyperlipidemic pancreatitis is gradually becoming more common.

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