How to choose long acting antihypertensive drugs for patients with high blood pressure?

When blood pressure rises, many doctors will recommend taking medicine to effectively control it, and generally choose mild drugs as the basic antihypertensive drugs. The most basic drugs are generally easy to use and taken orally, such as compound antihypertensive tablets or antihypertensive drugs containing traditional Chinese medicine. According to different conditions, you can reasonably choose the antihypertensive drugs that are suitable for you.

There are many common types of antihypertensive drugs on the market, and we must choose them in a targeted manner when taking drugs.

1. Angiotense II receptor anti-caking agents, such as Daiwen, Kosoya, Ambovi, etc.

2. Diuretic drugs, such as Shoubishan, antihypertensive No. 0, compound antihypertensive tablets, etc.

3. Vasoconvertase inhibitors such as Kaibotong, Lotin sin, Monol and so on.

4. Calcium ion antagonistic drugs, such as Novoxi, nifedipine, felodipine, etc.

5. Receptor blockers, such as betalux, conco, etc.

When using these drugs, you must pay attention to the instructions of the drugs, and at the same time, you should also follow the doctor's advice and pay attention to the method and dosage of the medicine.

When blood pressure is high, there are a number of other ways to control it. High blood pressure is often caused by a lack of vitamin D in the body, and timely exposure to the sun can have the effect of absorbing vitamin D. If you want to lower blood pressure, you can get in the sun properly, but in the summer, the ultraviolet rays are particularly strong, so it is best to choose at 10:0 in the morning

From 00 to 11:00, it takes about 20 minutes to do it each time.

Elevated blood pressure is now very common in life, and people with this symptom must measure their blood pressure in time every day and take medication to control it. At the same time, we must pay attention to in life, we must quit drinking, because drinking is harmful to health, and blushing often occurs after drinking, so drinking can easily lead to an increase in blood pressure, so in order to stabilize blood pressure, we must quit drinking.

1. Simple systolic or diastolic hypertension.

Simple systolic hypertension is generally more common in the elderly, is an independent risk factor for cardiovascular disease, the pulse pressure difference is too large, more prone to cerebrovascular disease and myocardial infarction, the first choice of low-dose diuretics, such as dihydrogram urinary or shoubishan, etc., pay attention to the adverse effects of hypokalemia, can be used at the same time potassium-sparing diuretic spironolactone (spironolactone) or amiloride, if the effect is not ideal, can be combined with calcium antagonists.

Calcium antagonists inhibit calcium from entering the cell by blocking cell voltage-dependent calcium channels, relax vascular smooth muscle and lower the peripheral room, while protecting the structural and functional integrity of vascular endothelial cells, anti-arteriosclerosis, and can prevent and reverse left ventricular hypertrophy and arteriolar sclerosis.

Care should be taken to use medium- and long-acting, controlled-release formulations, such as nittrandipine, nixodipine, nicardipine, felodipine, and long-acting nifedidine. Among them, nisoldipine is 100 times stronger than nitrandipine, which dilates veins at the same time, which is fat-soluble and most suitable for obese patients. Nitrandipine has a fast onset of action and a short duration of action, resulting in large fluctuations in blood pressure, with obvious negative inotropic effects, and is basically ineffective for post-exercise hypertension, so it should be avoided as much as possible, and only used for patients with high blood pressure who need to temporarily lower blood pressure rapidly.

Due to the increased peripheral vascular tone of diastolic hypertension, which is manifested as left ventricular systolic function in the early stage, drugs that are highly selective for peripheral blood vessels and can improve left ventricular systolic function should be selected, and long-acting calcium ion antagonists (CCBs) have good functions in this regard, such as nisoldipine, lasidipine, iladipine, and amlodipine.

1 Receptor blockers (such as terazosin, trandin, etc.) directly block 1 receptors, dilate volume blood vessels and resistance blood vessels, reduce cardiac pre- and post-load, and the effect of combination with CCB on diastolic blood pressure is ideal. Because angiotensin-converting enzyme inhibitors (ACE inhibitors) dilate both arteries and veins, they can be used in combination with CCB to achieve significant results.

There are many very good long-acting blood pressure medications, and it's hard to say which one is the best. Relatively speaking, the antihypertensive drugs that are suitable for patients are the best antihypertensive drugs for patients themselves. In clinical practice, the relative effect is relatively good, and there are relatively few drugs, such as perindopril, benapril, nifedipine controlled-release tablets, amlodipine, felodipine, irbesartan, valsartan, losartan, telmisartan, these drugs are relatively good first-line antihypertensive drugs.

In addition, such as metoprolol, bisoprolol, hydrochlorothiazide tablets, although the antihypertensive effect is not strong, but it can be combined with other antihypertensive drugs, and it also has a very good effect. In the process of medication, it is necessary to pay attention to monitoring blood pressure and heart rate, and regularly check liver function and kidney function.

Patients with hypertension need long-term oral antihypertensive drugs to control blood pressure, and there are five categories of antihypertensive drugs, including angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists, beta receptor antagonists, calcium channels and diuretics, among which the more long-term effect is the control tablets or sustained-release tablets of various drugs, which generally only need to be taken once a day.

Long-acting drugs are drugs that can stabilize blood pressure for a long time when taken once a day. The advantages of this class of drugs are, first of all, less impact on blood pressure fluctuations, can improve patient compliance, and are easy to use and will not be forgotten. Commonly used long-acting drugs include angiotensin inhibitors, such as valsartan, controlled-release tablets or extended-release tablets of calcium ion antagonists, and long-acting angiotensin transferase inhibitors, such as phenazepril, perindopril, fosinopril, etc.

Individualized medication, specific medication should be followed by the doctor's instructions.

Patients with high blood pressure need to go to the hospital to listen to the doctor's advice when choosing long-acting antihypertensive drugs, because not every drug is suitable for everyone, so it is correct to listen to the doctor's advice in terms of medication. Patients with high blood pressure need to go to the hospital to listen to the doctor's advice when choosing long-acting antihypertensive drugs, because not every drug is suitable for everyone, so it is correct to listen to the doctor's advice in terms of medication. Patients with high blood pressure need to go to the hospital to listen to the doctor's advice when choosing long-acting antihypertensive drugs, because not every drug is suitable for everyone, so it is correct to listen to the doctor's advice in terms of medication.

Patients with high blood pressure need to go to the hospital to listen to the doctor's advice when choosing long-acting antihypertensive drugs, because not every drug is suitable for everyone, so it is correct to listen to the doctor's advice in terms of medication. Patients with high blood pressure need to go to the hospital to listen to the doctor's advice when choosing long-acting antihypertensive drugs, because not every drug is suitable for everyone, so it is correct to listen to the doctor's advice in terms of medication.

1.Angiotensin-converting enzyme inhibitors (ACE inhibitors, pulis) and angiotensin-II receptor antagonists (ARBs, sartans).

ACE ARB can be used as a first-line drug for all types of uncomplicated hypertension, and patients with arteriosclerosis, diabetes, diabetic nephropathy or hypertensive nephropathy, or metabolic syndrome can also choose ACE ARB to lower blood pressure.

However, women who are pregnant, have high blood potassium, and have bilateral renal artery stenosis should not choose ACE inhibitors. Common acei class *** include dry cough and vasogenic edema (edema of the face, foot and ankle, etc.), and acei arb antihypertensive drugs cannot be used in the presence of these***.

Compared with ACE inhibitors, ARB antihypertensive drugs have fewer cases of dry cough and angioneurogenic edema, and if ACE inhibitors cannot be tolerated due to these two factors, ARBs may be an option.

2.Calcium ion antagonists (CCB, including dipines, verapamil, diltiazem).

It is also a very good first-line blood pressure lowering drug, and there are not many of them. In addition to being used for uncomplicated hypertension, patients with left ventricular hypertrophy, angina, peripheral arterial disease and other problems are recommended to prefer CA antihypertensive drugs.

In addition, some CA classes such as diltiazem, verapamil, and nicardipine may interact with certain statins through cytochrome CYP3A4 metabolism.

3.Beta-blockers (BB, lol, various types of Leck).

Hypertensive patients with persistent atrial fibrillation or rapid heart rate may be the first choice for BB antihypertensive drugs.

Patients with asthma or second- and third-degree atrioventricular block should not be treated with BB.

4.Diuretic.

There are two main categories, thiazide diuretics cannot be used in patients with gout, and potassium-sparing diuretics cannot be used in patients with renal failure and high blood potassium. 、.

Long-acting antihypertensive drugs are preferred to lower blood pressure, and long-acting antihypertensive drugs are preferred. Long-acting antihypertensive drugs take a long time and can maximize the concentration of the drug within 24 hours a day and keep blood pressure stable. This can reduce or avoid the harm caused to patients by high blood pressure and frequent fluctuations; Long-acting antihypertensive drugs can help patients with hypertension avoid missing medications; Long-acting antihypertensive drugs have good compliance and are convenient for long-term medication.

In general, the criteria for an ideal antihypertensive drug are: Positive efficacy, stable and long-lasting blood pressure lowering 24 hours a day; Small, easy to take, good compliance; Does not affect the patient's quality of life, especially sexual quality of life; It does not affect the metabolism of blood lipids, blood sugar and electrolytes in the patient's body; It can reverse the patient's heart, brain, kidney and arteriosclerosis and other lesions.

When choosing antihypertensive drugs for hypertensive patients, the following points should be followed:

1. Start with a small dose.

In order to reduce the risk of drugs and explore their sensitivity and adaptability to drugs, the smallest effective dose should be used at the beginning, especially for the elderly, and they must start with a small dose. If blood pressure is poorly controlled and there are no adverse effects, it is gradually increased to the usual dose or individual effective dose.

2. Preferential selection of long-acting preparations, as far as possible to use long-acting drugs that are administered once a day and have a 24-hour antihypertensive effect, so as to effectively control night blood pressure and morning peak blood pressure. More effective in preventing cardiovascular and cerebrovascular complications.

3. Reasonable combination of drugs.

Reasonable combination of drugs can reduce drug toxicity and achieve the best antihypertensive effect. When blood pressure control is not satisfactory, preference should be given to adding a small dose of another class of drugs, rather than increasing the dose of the drug already used, let alone adding the same antihypertensive drug.

4. Individualize the selection of antihypertensive drugs suitable for patients according to the specific situation of the patient, drug effectiveness and drug resistance, taking into account the patient's economic conditions and personal wishes.

5. In the process of applying antihypertensive drugs, do not frequently change different antihypertensive drugs.

The onset time and peak time of dehypertensive blood pressure varies. The peak time of long-acting preparations is slow, and it is necessary to wait patiently and carefully observe the efficacy and quality, and frequent dressing changes may miss good antihypertensive drugs and delay the first time.

There are five main classes of hypertension drugs, including calcium antagonists, angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists, diuretics and receptor blockers, and other antihypertensive drugs. The methods of choosing antihypertensive** drugs are:

1. It is recommended to use long-acting antihypertensive drugs, that is, drugs that are taken once a day and can last for 24 hours;

2. If a small dose of long-acting drugs is used in combination, if a single drug is used, increasing the dose will increase the adverse reactions, such as the antihypertensive effect of calcium ion antagonists is not good, and the adverse reactions will increase after increasing the dose, such as anterior tibial edema, gingival hyperplasia, etc.;

3. In the process of blood pressure reduction, it is recommended that the blood pressure should be lowered in a reasonable and individualized manner.

When choosing antihypertensive drugs for hypertensive patients, they should choose according to the doctor's examination, and we need to understand that drugs should never be chosen at will. Antihypertensive drugs are not lifelong, they need to be reused, if your blood pressure is maintained in a stable state for a long time, then you don't need to take blood pressure drugs anymore. But if your blood pressure fluctuates, then you also need to go and maintain your health by taking blood pressure medication.

Because everyone's physical condition is different, especially some middle-aged and elderly groups, which are high-incidence groups with high blood pressure, and middle-aged and elderly groups not only have the problem of hypertension, but also other chronic diseases. Therefore, when doctors prescribe medicines to everyone, they will also prescribe medicines according to various physical conditions. Everyone's physical condition is different, so there is a medicine that may work for others but not for you.

Therefore, when you choose a medicine, you must go to the hospital for an examination, tell the doctor about your physical condition, and the doctor will give you a better advice after a comprehensive examination.

Patients with high blood pressure do not need to take medicine for life, and taking medicine can indeed help us maintain stable blood pressure, but it does not need to take medicine for life. If we need to take medicine for the rest of our lives, then it is a three-point poison, and it will inevitably have a certain impact on our body. When your physical condition is already very good, then you can alleviate your disease in other ways, and you don't have to take medicine.

It is not recommended that you take medicine all the time, if you measure many times, and persist for a long time, and find that your blood pressure is relatively stable, then we do not need to take medicine again, you can also choose to go to the hospital for a check-up, and tell the doctor about your physical condition. The doctor will also judge whether you need to take medicine according to your specific physical condition? Regular taking of medicine will actually have a certain impact on the body, so it is not recommended that you take medicine regularly.