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Cefixime dispersible tablets belong to the third generation of cephalosporins, and their antibacterial spectrum is relatively wide, so they are widely used in clinical practice. Although there is no evidence in animal tests that it has obvious teratogenic effects, or secretion through animal milk, and no clinical studies have found that it can be secreted through human milk, it is recommended to use cefixime dispersible tablets with caution during lactation for the sake of safety. If you must take cefixime dispersible tablets, it is recommended to stop breastfeeding.
Cefixime dispersible tablets have good antibacterial effect on most of the gram-positive bacteria and negative bacteria, such as streptococcus, pneumococcus, gonorrhoeae, and influenza bacilli, all have strong antibacterial effect, this mechanism is mainly to prevent the synthesis of cell wall, and has strong stability to the -lactamase produced by various bacteria.
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Can you breastfeed after eating cefixime? Breastfeeding mothers can breastfeed after taking cefixime. After the mother eats cefixime, only a small amount of the drug can be absorbed by the baby through the milk, and the amount of these drugs absorbed by the baby will not have an impact on the baby's body.
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The U.S. Food and Drug Administration classifies drugs as A, B, C, D, and X according to their risk of use during pregnancy. Class A is the safest, and studies have confirmed that the drug is not dangerous in pregnant women, and Class X is teratogenic and absolutely contraindicated during pregnancy. At present, there is no clinical grade A antibiotic, and the highest safety level of antibiotics is B, of which penicillin and cephalosporins are class B.
Grade B refers to the absence of risk in animal studies, but for which research data are not available or insufficient; and toxic to animals, but not dangerous in human studies. Breastfeeding women can use these antimicrobials, and it is recommended to stop breastfeeding while taking the drug.
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He came back after 72 hours to feed, and he had to drink plenty of fluids during that time.
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Cefixime tablets, current studies have proved that taking drugs during lactation can be secreted through breast milk, so if you are taking cefixime tablets during lactation, you must pay attention to stop breastfeeding, otherwise it may have a certain impact on the child. In general, it is safer to stop cefixime tablets for seven days before breastfeeding. Breastfeeding is not recommended while taking cefixime tablets, as it is clear that milk production can affect the child's development.
Cefixime tablets belong to the class of anti-inflammatory drugs of the cephalosporin class. There may be some adverse reactions during the consumption process. The most common of these are gastrointestinal reactions that cause abdominal pain, diarrhea, nausea, vomiting, heartburn, and acid reflux; Then there is the change in **, which may cause local blisters and annular erythema, similar to urticaria-like changes; It is to cause problems in the blood system, such as agranulocytosis, leukopenia, erythrocytopenia, thrombocytopenia, etc.; It may also have an impact on liver and kidney function.
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Can you breastfeed cefixime after eating? I think it's better to feed at intervals in this case, and it needs to be more than four hours apart, and it needs to be digested in the body, so I think breastfeeding is the best way.
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It is advisable for breastfeeding women not to take penicillin or cephalosporin medicines, which can pass through breast milk and may cause allergies in infants.
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Can you breastfeed cephalosporine? This doesn't seem to have an effect, so you can consult a doctor.
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Mastitis is a common problem for breastfeeding mothers, especially new mothers. Because mastitis needs **, many times mothers will refuse to use antibiotics for fear of affecting the baby, and there are also mothers who take antibiotics and stop breastfeeding because it will affect the baby. In fact, many times it is safe to use antibiotics.
Drug metabolism has a half-life (t1 2), and the half-life of a drug generally refers to the time it takes for the maximum concentration of the drug to decrease by half in the plasma. The half-life of a drug reflects the speed of elimination (excretion, biotransformation and storage, etc.) of the drug in the body, and indicates the relationship between the time the drug is in the body and the blood concentration, which is the main basis for determining the dose and frequency of administration. Different people have different elimination of drugs, and the half-life we usually talk about is an average.
Generally, drugs disappear in the body after 5 half-lives. The half-life of cefixime is 3-4 hours.
According to the drug safety level, cefixime is an L2 level antibiotic, and L2 drugs are also relatively safe. Cephalosporin drugs generally do not need to be stopped during lactation. Occasionally, it may interfere with the baby's intestinal flora and cause diarrhea, which is usually mild and manageable.
This is also a common *** that antibiotics may produce. If you are worried, you can give your baby some probiotics to prevent, or give your baby probiotics when he has mild diarrhea. This is very common in clinical practice and is not an indication for stopping breastfeeding.
L1 grade: The safest, many nursing mothers do not observe an increase in *** to their babies after taking the drug. Controlled studies of breastfeeding women have not been shown to be dangerous to the infant and may be less harmful to the infant than to the breastfeeding. Or the drug cannot be absorbed orally in the infant.
Grade L2: There is no evidence of an increase in the use of the drug in nursing mothers in a limited number of studies, and there is little evidence of the risk of the use of the drug in nursing mothers, and the drug ingested through breastfeeding does not have a corresponding clinical effect on breastfeeding infants.
Grade L3: No controlled studies have been conducted in breastfeeding women, but adverse effects of feeding infants may be present or controlled studies have shown only mild, non-fatal effects***.
We have made a brief list of commonly used antibiotics for easy reference by mothers;
li: amoxicillin, penicillin, cefadroxil, cefazolin, cefoxitin, ceflatin, cephalexin, cefazoloxime, ceftazidime
L2: Azithromycin, Hicklaw, cefixime, cefoperazone, cefotaxime.
Antipyretic LI: Ibuprofen.
In short, the mother who asked the question above does not need to worry about the safety of breastfeeding, and if the baby is not allergic to the drug, the current research shows that there is no need to stop breastfeeding. In addition, a constant outflow of milk is good for mastitis, and continuing breastfeeding is the best way to do it.
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It is relatively safe, it is possible to breastfeed, and the lactation classification of the drug can be consulted on the "medication assistant". L1 and L2 drugs do not affect breastfeeding. L3 drugs should be used with caution, and L4 and L5 drugs are not recommended for lactation.
Cephalosporins are usually in the L1-L3 category, and it is better to check the lactation grade of the drug before deciding how to deal with it. Pay attention to the time of taking the medicine!
Try to take the medicine after the feeding; Or take the medicine before your baby's longest round of sleep. For example, take the medicine after the last feeding in the evening.
2. Short-acting drugs and long-acting drugs
Different drugs are metabolized at different rates in the body. Short-acting drugs are those that need to be taken multiple times a day and have an effect of less than 6 hours at a time. They are excreted more quickly from the bloodstream and milk, preventing the drug from accumulating in the baby's body.
3. Traditional Chinese medicine, refusal!
As for traditional Chinese medicine, due to its complex composition, there is still a lack of sufficient evidence on the safety of the drug for pregnant and lactating women, so it is not recommended for expectant mothers and breastfeeding mothers to take it rashly.
4. L1 and L2 levels are safer, and L3 levels are used after trade-offs.
According to the grading of lactation medication, choose the appropriate ** drug. In general, L1-L3 drugs are safe, and there is no need to stop breastfeeding. However, try to choose L1 and L2 drugs, L3 needs to be used by doctors to weigh the pros and cons.
Remember to tell your doctor that you are a breastfeeding mother.
It is easy to know the specific grade of the drug. For example, we checked "ibuprofen" and chose the following "Motrin (Buprofen Suspension Drops)", we can see that it is an L1 drug, and it is safer for breastfeeding mothers to take.
In short, if you are sick during breastfeeding, tell your doctor about your situation and be cautious about taking your medicine. Most of the drugs go into the breast milk, but the dose that goes into the milk is much smaller than we think (usually about 1% of the mother's intake, or even less), so you don't need to "talk about the discoloration of the medicine".
If you take a drug that is contraindicated during breastfeeding, you can usually resume breastfeeding after 5 half-lives. During this period, it is necessary to empty the milk regularly to prevent mastitis and prevent the decline in milk production. The half-life is also available.
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Breastfeeding women can breastfeed after taking cephalosporin. People with a history of cephalosporin allergy are contraindicated against cephalosporin antibiotics. The choice of antibiotics must be strictly clinically indicated, and drugs should not be blindly abused to prevent the recovery of the disease or the occurrence of superinfection.
And do not drink alcohol when taking cephalosporin antibiotics, and do not eat foods and drugs containing alcohol to prevent the occurrence of disulfiram reaction, which is life-threatening.
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During lactation, if you need to add antibiotics, it is recommended to choose cephalexin, or compound aminophenamine capsules, which can be fed, has no effect on the child, and does not go through milk metabolism, so there is no need to worry. When taking oral medications, it is recommended to drink plenty of water, pay attention to rest, maintain sufficient sleep time, and dynamically observe the changes in the condition to see if there is fever, or symptoms of nausea, cough, and phlegm. If the symptoms are typical, you need to go to the hospital, sometimes need infusions**, pay attention to nutrition and exercise, and eat plenty of fresh vegetables and fruits.
There are also foods rich in protein and iron, such as fish, pork ribs, eggs and pork liver. When feeding, you must observe the child's reaction to see if the child has other symptoms, and you must also pay attention to your own body and medication.
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After eating cephalosporin, as long as it is taken according to the normal dose, it will not affect the normal secretion of milk and the quality of milk can be fed.
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Lactating mothers are not able to take any medicine, cephalosporin should be no problem, and antipyretic drugs are also available. However, psychotropic drugs cannot be eaten, and you can take oral drugs for two hours before breastfeeding.
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Breastfeeding is not recommended while taking the drug.
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As long as you take the medicine, it is according to the instructions. There won't be any problems. It is okay to breastfeed your child.
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Cephalosporin is an antibiotic drug, which is specially used to reduce inflammatory symptoms, generally speaking, it is best not to feed the baby within 24 hours after taking such drugs, so as to avoid the baby's allergic reaction to the drug and cause the baby's disease.
Can't eat it, it's an allergic reaction and should be changed.
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