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Anemia is a common manifestation of neoplastic diseases, with an incidence of up to 10% to 40%, and the incidence of anemia in patients with lymphoma, colon cancer, gastric cancer, multiple myeloma, lung cancer, ovarian cancer, etc. can reach 50% to 60%. At present, it is believed that the common causes of anemia in cancer patients mainly include the following:
1. Malnutrition: Tumor is a wasting disease, its growth consumes nutrients in the body, and long-term malnutrition is easy to cause anemia in patients. According to statistics, digestive tract tumors account for the majority of malignant tumors found with anemia as the first one.
2. Tumor metastasis: extra-bone tumor metastasis to the bone marrow or intramedullary disease itself can interfere with the hematopoietic function of the bone marrow, destroy hematopoietic cells, inhibit the growth of red blood cells and cause anemia.
3. Radiotherapy and chemotherapy inhibit bone marrow function: Tumor patients can often inhibit bone marrow function during long-term radiotherapy and chemotherapy, resulting in necrosis of pluripotent stem cells and erythrocyte precursor cells, and a decrease in erythropoietin levels, resulting in anemia.
4. Bleeding caused by tumors: surface necrosis and ulcers or cauliflower-like growth of malignant tumors often cause bleeding, which can cause hemorrhagic anemia.
5. Acute and chronic inflammation caused by tumors: Bone marrow hematopoietic function can be inhibited when cancer patients are infected, such as lung cancer and bronchial cancer causing bronchial obstruction and secondary lung infection can aggravate anemia.
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Tumor patients are not all prone to anemia, almost all common benign tumors are not accompanied by anemia, only the advanced stage of malignant tumors will have obvious wasting changes, resulting in adverse effects, so that the lack of hematopoietic raw materials, the loss of blood formed components, and the poor utilization of nutrients cause anemia in different Chengdu.
Malignant tumor anemia is also called cancerous anemia, and there are several main reasons for cancer anemia:
1. Cancer invades or metastasizes the bone marrow, sometimes bone marrow aspiration will find cancer cells in the bone marrow, so as to confirm the diagnosis of metamorphosis and so on.
2. Cancer will lead to an increase in the consumption of the body, which will lead to dystrophic anemia.
3. Cancer occurs in some special parts, such as the stomach, colorectal, pancreas, etc., resulting in gastrointestinal bleeding, thus causing hemorrhagic anemia.
Therefore, almost all cancers cause anemia, but the specific mechanism is different.
In addition, many endogenous tumor hormone-like substances and tumor distant effect bone marrow suppression are also important factors causing anemia.
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Cancer patients will have varying degrees of anemia after surgery, radiotherapy, chemotherapy and targeted **, and hemoglobin levels may be found to be low during routine blood tests. In particular, stomach cancer, colorectal cancer, lung cancer, breast cancer and liver cancer are most prone to anemia, once anemia occurs, it will reduce the ability of the blood to carry oxygen, causing a lack of oxygen to vital organs, so that it affects **and the next step**. There are mainly the following reasons:
1) Lack of nutrients in the body.
Because gastrointestinal surgery, coupled with radiotherapy and chemotherapy, the synthesis of hemoglobin is insufficient, including iron, B vitamins, folic acid, trace elements and high-quality proteins, etc., can not better intake of these nutrients, or the absorption is reduced, coupled with excessive consumption and loss, resulting in anemia.
2) Adverse effects of radiotherapy and chemotherapy.
Most cancer patients need radiotherapy and chemotherapy, which can kill cancer cells in the body, but normal hematopoietic cells are not spared, resulting in a decrease in white blood cell and red blood cell counts, resulting in anemia. In addition, radiotherapy and chemotherapy can easily cause bone marrow hematopoietic dysfunction, which reduces the amount of red blood cell production, thereby causing anemia.
3) Chronic inflammation.
Because cancer patients have weak resistance and immunity, they cannot make better use of the nutrients that can synthesize hemoglobin, especially iron, and cannot better transport and absorb and utilize iron ions, or cause insufficient erythropoietin, which eventually causes anemia.
4) The cancer itself.
Certain cancer symptoms can cause blood loss, including hemolytic anemia in patients with lymphoma, and heavy bleeding and blood in the stool in patients with gastrointestinal and gastrointestinal cancers.
Most cancer patients have iron deficiency anemia, mild anemia does not require medication**, which can be dealt with by eating more foods containing hematopoietic raw materials, including protein, folic acid and vitamin C. In addition, it can be supplemented by blood tonic agents such as blood protein peptides, and the hemoglobin of Baibei Youjia is rich in heme iron and blood protein polypeptides, with sufficient substrates to meet the needs of hemoglobin synthesis and more efficient nutritional blood supplementation.
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Answer]: Iron deficiency anemia is a type of microcytic hypochromic anemia caused by a decrease in hemoglobin due to iron deficiency in the body.
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Answer]: C pernicious anemia, also known as megaloblastic anemia, is relatively rare in China, ** often caused by pregnancy, lactation, gastric malabsorption, malnutrition or oral folic acid antagonists. Pernicious anemia belongs to the Yanchanheng group of the three groups of nuclear maturity disorder anemia, which is rare in China, and the basic defect of this disease lies in the disorder of gastric factor secretion.
Gastric factor production accelerates the absorption of vitamin B12 in the mucosa of the small intestine. Therefore, patients with this disease have vitamin B12 malabsorption disorders, resulting in clinical manifestations related to vitamin B12 deficiency. Therefore, the ** of pernicious anemia is vitamin B12 deficiency (C pair) in the body.
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