What are the effects of agomelatine tablets and what kind of people are they suitable for

Who is it suitable for? Depression is a common mood disorder characterized by significant and persistent depressed mood.

The patient's depressed mood is not commensurate with his or her situation, and in severe cases, suicidal thoughts and behaviors may occur. Most cases have a tendency to reverse, and most of them can be relieved with each attack, and some may have residual symptoms or become chronic. Patients in a depressed state suffer great mental and even physical pain, affecting life, affecting the patient's family or occupational function, and the risk of suicide is very high.

It is best to receive timely, adequate and thorough ** (i.e., clinical cure in the acute stage** and sufficient consolidation** and maintenance**) once the depression is identified, otherwise it will lead to the chronicity and refractory treatment of the disease. Agomelatine has obvious antidepressant effect, and the onset of action is relatively fast, the efficacy is relatively certain, and it is suitable for moderate and severe depression.

For patients, it can effectively relieve depressive mood and accompanying anxiety, tension and somatic symptoms, and has a good effect on depression and accompanying anxiety symptoms. Agomelatine is a new breakthrough in the field of depression, and its unique mechanism of action avoids the occurrence of drugs to the greatest extent while quickly and effectively exerting its antidepressant efficacy. Buy agomelatine tablets.

Choose a Conado pharmacy.

Agomelatine tablets are imported drugs produced by the French pharmaceutical factory Servier and then imported into China for sale by distributors. At present, there may be differences between imported drugs and domestic drugs in the following two aspects:

1. In terms of **, imported drugs are higher than domestic drugs. Because foreign drugs enter the domestic market first to obtain a license, and drugs imported from abroad also have to pay tariffs, freight and other expenses. In addition, most of the drugs entering the Chinese market from abroad are original varieties, and huge research funds have been spent in the development process.

Most of the domestic drugs are generic drugs, and the research cost is less, coupled with the domestic labor cost and other reasons, the cost is relatively low.

2. In terms of efficacy, there will not be much difference between imported drugs and domestic drugs. Many people think that the standards of foreign drugs are somewhat higher than those of domestic products, and they are higher than domestic drugs in terms of purity and absorption. In fact, this is not absolute, and the products of some domestic drug manufacturers are no less than imported drugs.

In addition, domestic drugs are more suitable for the physique of the Chinese people in terms of dosage and use methods, and sometimes they are more suitable for the Chinese people, and the efficacy of the medicine will be better.

Therefore, if you need to take Weixin (agomelatine tablets), please choose imported drugs or domestic drugs according to your actual situation.

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The effect of agomelatine is okay. The effect of agomelatine tablets on ** depression and relieving sleep disorders is more positive.

Cases of liver injury have been reported in post-marketing use, including liver failure (death or liver transplantation has been reported in a few patients with liver risk factors), liver enzymes greater than 10 times the upper limit of normal, hepatitis, and jaundice (see [Adverse effects]). It is more common in the first few months of the first month. The pattern of liver damage is mainly liver cell damage.

Serum aminotransferase levels usually return to normal in these patients after discontinuation of this product. All patients should be carefully monitored closely before initiation and throughout the period, especially if they have risk factors for liver injury or are used in combination with other drugs that may cause liver damage.

Related information

There are no or limited clinical data on the use of agomelatine in pregnant women (less than 300 cases). Animal studies have not found direct or indirect damage to pregnancy, embryonic fetal development, childbirth, or postpartum development. As a precautionary measure, agomelatine should be avoided in pregnant women.

It is unclear whether agomelatine metabolites are secreted into human milk. Available animal pharmacodynamic toxicological data have confirmed that agomelatine metabolites can be secreted into rat milk. The risk to the newborn baby cannot be ruled out.

It is necessary to consider the benefits of breastfeeding to the infant and the benefits to the female patient before deciding whether to stop breastfeeding or discontinue the product.

The above content refers to Encyclopedia-Agomelatine.

1. Agomelatine, with a new trade name, is a chemical. The chemical name is N-[2-(7-methoxynaphthalene-1-yl)ethyl]acetamide, the molecular formula is C15H17NO2, and the molecular weight is.

2. Functional indications. Agomelatine tablets, the first melatonin receptor agonist, have a good antidepressant effect. It is mainly used for anti-depression, anti-anxiety, adjusting sleep rhythm and regulating biological clock.

3. Adverse reactions. Common symptoms include headache, nausea, and fatigue. Gastrointestinal adverse effects are rare.

Chinese name: agomelatine.

Chinese alias: N-[2-(7-methoxynaphthalene-1-yl)ethyl]acetamide English name: agomelatine

Synonyms: 138112-76-2; aglomelatine; n-[2-(7-methoxy-1-naphthyl)ethyl]acetamide; n-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

cas:138112-76-2

Molecular Formula: C15H17NO2 Molecular Structure:

Molecular weight Density: Boiling point °C at 760 mmHg Melting Point: 107-109°C Flash point °C Appearance: white solid

Melatonin-based drugs.

Agomelatine - another "blockbuster" drug in the category of mental illness.

The melatonin analogue agomelatine is both the first melatonin receptor agonist and a serotonin-2c (S-HTX) receptor antagonist. Animal experiments and clinical studies have shown that the drug has antidepressant, anti-anxiety, sleep rhythm adjustment and biological clock regulation, and its adverse reactions are few, no adverse effects on sexual function, and no withdrawal reaction has been seen.

The first melatonin receptor agonist, agomelatine (valdoxan), is a melatonin analogue, which is also a serotonin 2C (5-HTAC) receptor antagonist. Melatonin has a similar affinity for its receptors MT1 and MT2, and agomelatine is similar to it, and also has a high affinity for cloned human melatonin receptors MT1 and MT2 (Ki, respectively. Clinical studies have shown that agomelatine has a good effect on patients with depression and has very few adverse reactions.

Agomelatine was developed by Servier and is currently on the market.