How is amyloidosis treated? Is amyloidosis serious? What treatments are available?

Amyloidosis is a clinical syndrome in which amyloid is deposited between cells in various organs of the body due to a variety of reasons, resulting in the gradual loss of function and failure of the affected organs. It includes a group of diseases, which were first discovered by German scholars in 1838, and in 1854 famous pathologists called it the iodine test, or iodine-sulfuric acid test, and found that it was like starch purple-blue and named amyloid. Its degeneration usually involves multiple organs, and the clinical symptoms depend on the degree of damage to the organs involved and the affected organs, mainly kidneys, heart, liver, gastrointestinal, tongue, spleen, nervous system, etc., and there are many clinical classifications.

For it, there is a special **, amyloid, especially in patients with multiple myeloma, with the elimination of clonal plasma cells, but this disease cannot be **, and amyloid deposition is difficult to reverse. The most successful treatment of amyloidosis** is the prophylactic use of colchicine in patients with familial Mediterranean fever. In addition, there is general support** that sodium intake should be restricted, diuretics should be given if necessary, and dialysis should be given if renal failure occurs**; Sodium restriction and diuretics are also useful in congestive heart failure; Elastic stockings or tights may help correct orthostatic hypotension.

In conclusion, this disease** is very difficult.

**Amyloid dyspathy**. If the itching is particularly severe, some antihistamines such as loratadine or fexofenadine hydrochloride can be taken by mouth. It can also be used externally, Aoshen, triamcinolone acetonide acetate, ** when kidney failure, the specific cause of kidney failure should be found first, and then**.

If necessary, we can relieve symptoms with dialysis and kidney transplantation.

There are many ways to get amyloidosis. They can be relieved by taking medications such as vitamins or hormones. It should be adjusted according to the patient's condition.

**Clinical classification of amyloidosis can be divided into several types. Our approach varies from type to type. For the nodular type, surgical excision or freezing may be considered, but it is easier to use this method simply**.

Some patients** have amyloidosis and may have nodules. Given this condition, it is generally recommended to undergo surgery** and remove the nodule. For nodular amyloidosis, electrocautery or freezing may also be used**, but these methods are easy to use and therefore can only be observed and reconfirmed periodically, and SIDO considers the disease to be dominant autosomal inheritance.

In some cases, there are abnormalities in lipids and proteins in the blood, which are thought to be related only to metabolic disorders. Some patients have a family history. It is more common in men than in women, more often in young people, and may be extended by years or decades.

Pure ** does not work well. If there is a nodule, surgery or laser** may be used. These methods can achieve the goal of sexual healing, but in order to avoid later stages, regular check-ups are required.

Antihistamines can be taken by mouth. It can be encapsulated with high-potency corticosteroid ointment, small lesions can be injected with triamcinolone acetonide, nylon and other lesions, retinoid cream for topical use, or salicylic acid preparations or ointments, tar and other keratinocytes and promoters of keratinocyte tinctures. Liquid nitrogen freezing is also available**.

In liver transplant TEM, the transformed transtyoxin was used to remove the synthesis site of the mutant protein, and the hereditary amyloidosis was successfully achieved.

Amyloidosis is not very serious, and it is not contagious, and the main manifestation is ** special itching, which can be relieved by some drugs.

If it's not serious, you can buy some ointments, you can also buy some oral medicines, or you can close **, which is very effective.

Severe. In this case, you can use surgery**, or you can be assisted by medication**, and you can also choose the way of traditional Chinese medicine**.

1.Symptomatic**For general loss of appetite, belching, etc., exercise promoters can be given. Intravenous hypernutrition in patients with severe diarrhea and intestinal pseudoobstruction can achieve certain effects.

For intractable constipation, tetracycline antibiotics are effective, and minocycline (dimethylaminetetracycline) 200 mg per day may improve fecal abnormalities in initial cases.

2.The drug **dimethylsulfoxide (DMSO) has the effect of breaking down amyloid and is now being trialled for clinical use.

3.Surgery should be avoided as much as possible, as wounds are extremely difficult to heal. The disease is differentiated from gastrointestinal malignancy due to progressive systemic failure and a variety of gastrointestinal symptoms.

Because of abnormal movement of the digestive tract, it is necessary to distinguish it from diabetic gastrointestinal lesions, especially in patients with alternating constipation and diarrhea, and it should also be distinguished from ulcerative colitis, Crohn's disease, and ischemic enteritis. Hemorrhage, infarction, and perforated amyloid deposition into the capillaries can cause ischemia, erosion, and even ulceration due to vascular disorders, and ulcer bleeding may cause hematemesis and hematochezia. It also causes infarction of the sigmoid colon and perforation of the ileum.

Intestinal obstruction deposits a large amount of amyloid in the smooth muscle of the gastrointestinal tract, and then autonomic dysfunction causes motor dysfunction, causing symptoms of gastrointestinal obstruction. The prognosis of patients with amyloidosis is poor, which is associated with the progression of amyloidosis, with primary and myeloma having the worst prognosis, with 36 patients reported with this disease and an average survival of 11 months. A total of 47 cases were reported, 50% of whom died within 1 year of observation, and the main causes of death were heart and kidney failure and cachexia.

Secondary survival is about 45 months, and hereditary survival such as FAP can be as long as 5 to 10 years. No relevant information is available. Of all the types of systemic amyloidosis, the digestive tract is one of the most susceptible organs.

The incidence of gastrointestinal symptoms varies with the type, ranging from about 70% in primary amyloidosis and about 70% in secondary amyloidosis. However, with detailed histologic examination, amyloid deposits can be detected in the digestive tract in almost all patients with systemic amyloidosis, regardless of clinical symptoms.

I have had amyloidosis on my back for several years. I have taken medicine for two or three months, but I didn't expect it to get better, there is no numbness on the arm to the touch, and the foot and eye are also much better.

Powdery deposition refers to a disease caused by the deposition of amyloid in tissues or organs, and is not actually related to starch. The disease is thought to be autosomal dominant or related to a metabolic disorder. Depending on the organ involved, it is divided into systemic or **amyloidosis, and these two types are primary and secondary.

Depending on the lesions, there are different types of amyloidosis: lichen amyloidosis, maculated amyloidosis, mixed amyloidosis, nodular amyloidosis, and**heterochromic amyloidosis.

Consider getting a food allergy test (also known as a "food intolerance test"), which is now available in many major hospitals

According to a point of view in the medical community now, it is that those foods that people eat often cause chronic symptoms in some people (such as your ** amyloidosis), and it is not easy to find the cause For a simple example, milk is good for the body, right? Most people think so, but some children vomit and diarrhea after two days after drinking milk, which is caused by milk intolerance

In the food intolerance test, you will see these absolutely unexpected items: tomatoes, eggs, rice, soybeans, pork, ......These are our most common foods, and no one would have thought that they can cause physical diseases, but they may cause various chronic diseases: bad breath, asthma, arthritis, etc., including **amyloidosis!!

And because ** is very hidden, the onset of symptoms is delayed (one or two days or even a year or two after eating food), and the cause is basically not found with general detection methods.

It is very simple to do a test, just take a few milliliters of blood, and there are combinations of four, seven, and fourteen. If there is a severe intolerance to food, it is very simple, as long as you avoid eating for a period of time, as little as a week, more than half a year, if it is caused by food, you can basically **, and you will not do it again. The doctor will give a recommendation for the specific ** plan.

You might as well give it a try.

Amyloidosis refers to a chronic disease in which amyloid is deposited in normal tissues without involving other organs, which is not clear, mainly due to the symptomatic treatment of drugs of traditional Chinese and Western medicine, and the choice of specific drugs needs to be determined in combination with the actual situation of the patient.

Antihistamines may be taken by mouth. Topical high-potency corticosteroid ointment encapsulation. Small patches of skin lesions can be injected into the lesions such as triamcinone and prednisolone.

0 1 Tretinoin cream for external use, or salicylic acid, tar and other keratin relaxants and keratin promoters tincture for external use. Liquid nitrogen freezing can also be used**.

Precautions: 1. Pay attention to personal hygiene and keep it clean.

2. Try to be gentle and thorough when cleaning.

3. Susceptible people should avoid using skin care products with too much oil to prevent clogging pores.

4. Increase physical activity and improve the body's ability to resist disease.

5. Try to avoid trauma, if there is a wound, it should be disinfected in time, and kept clean, try to make it dry, and do not provide a warm and humid environment for pathogenic bacteria. Pay attention to avoid excessive friction in life, avoid using toiletries that are too alkaline, etc.

**Amyloidosis,**Two months later** the surface has improved significantly, and then focus on relieving itching.

Suggestion: Hello! Amyloidosis is a heterogeneous disease in which a group of proteins are deposited between cells with abnormal fibrous structures, resulting in changes in the structure and function of tissues and organs, resulting in corresponding clinical manifestations.

Therefore, when fiber-like vitamins are exposed to iodine and sulfuric acid, they react similarly to starch, so they are named "amyloidosis" and are still used today. Amyloidosis can be hereditary or acquired; Deposits can be localized or systemic; The course of the disease can be benign or malignant. ** Principles of amyloidosis.

So far, there is no specific method to reduce the foci of amyloid deposits, and the focus of clinical management is to reduce the supply of amyloid precursor white, and a reasonable ** plan should include the following 4 aspects: Control of the primary disease. Reduce the production of amyloid fiber precursors, such as the use of immunosuppressants to control the acute inflammatory response in patients with amyloidosis type AA, combined with chemotherapy to inhibit the production of amyloidosis al antibody light chain.

Orthotopic liver transplantation reduces the production of protein fiber precursors in hereditary amyloidosis, and patients with end-stage renal failure undergo kidney transplantation as soon as possible to facilitate the clearance of 2 microglobulins. There is no specific method to promote the resolution of amyloid deposition. Symptomatic support**:

Symptomatic support** can delay the failure of target organs, improve the quality of life, and prolong survival; Organ failure such as renal failure, refractory heart failure, and heart transplantation have some value. Some amyloidosis can be prevented, such as colchicine for FMF amyloidosis and early kidney transplantation for H A amyloidosis. Wishing you good health!