Why blastocyst transfer is more likely to improve the success rate

IVF assistant (18976469050): 1. Blastocyst transfer is closer to the physiological implantation time of natural conception.

In the process of natural conception, the fertilized egg moves from the fallopian tube to the uterine cavity just as the blastocyst stage embryo, and the endometrium is synchronized with the development, so the implantation of the embryo will be smoother. If we also transfer blastocyst stage embryos into the uterus during IVF preparation, and the embryo and endometrium develop synchronously, then the success rate of IVF will be relatively high.

2. Selection of high-quality embryos.

In the process of in vitro cyst culture, blastocyst culture is actually the process of selecting embryos. Some defective embryos with no developmental potential are further eliminated through the cultivation of the sac, so as to achieve the selection of survival of the fittest.

3. Overcome developmental retardation.

In general, embryos will be stunted on the second to third day of in vitro culture, and if the embryos are transferred into the womb of the expectant mother, the transfer will also result in a failed transfer. As long as the embryo successfully forms a blastocyst, it means that the embryo has survived the development retardation, and the success rate of the test tube will be relatively higher.

Blastocysts have a higher success rate than fresh embryos, but the cost of blastocysts is higher. And not all fresh embryos can be cultured into blastocysts, such as 15 eggs, the success rate of cultivating into fresh embryos is 90%, about 12-13 embryos, and then the success rate of fresh embryos cultured into blastocysts is 50%, so in the end about 6 blastocysts can be cultured.

All say that, but the quality of the embryo is also high. The success rate of cultivation is not high.

Hello! Compared with the general day-day embryo transfer, blastocyst transfer is more in line with natural physiological phenomena, which can improve the embryo implantation rate, thereby reducing the rate of multiple pregnancy, and can effectively prevent the occurrence of ectopic pregnancy.

I am a cultured blastocyst, 16 embryos, and in the end there are only 4 left, if there are not many embryos, our doctor here will not recommend raising them for 5 days, because cultured blastocysts are also very risky, unless your embryos are of very good quality. But the success rate of blastocysts is really high, 3-day embryos are decomposed by themselves, 5-day embryos, is hospital-assisted decomposition, and cells can reach hundreds, so sisters can rest assured to be mothers. On the twelfth day of my blastocyst transfer, on the eighth day, I tested the squadron leader, and I was successful once, I wish my sister a good pregnancy!

I have heard many sisters say that the success rate of blastocysts is higher than others.

The survival rate of frozen embryos is 70%, and the survival rate of capsule thawing is 90%.

From the embryonic point of view, the success rate of blastocysts will theoretically be a little higher!

Reason 1: Blastocyst transfer is closer to the natural growth of the embryo.

The culture and transfer of blastocysts are closest to the various stages of embryo growth from the fallopian tube to the implantation of the uterus in the natural growth, according to the law of nature, the embryo is in the fallopian tube when it develops to the stage of 4-9 cells. But when it reaches the uterus, the embryo develops into a blastocyst and implants. Therefore, the natural environment, nutrients and prepared endometrium are the best environment for the blastocyst stage, that is, the blastocyst transfer is easier to implant and the success rate is relatively higher!

Reason 2: Blastocyst culture is conducive to embryo screening.

Blastocyst culture can be used for initial embryo screening, and embryos with abnormal eggs or chromosomes cannot develop to the blastocyst stage. Therefore, blastocyst culture can preliminarily determine whether the embryo has chromosomal abnormalities, and if there is chromosomal abnormalities, it cannot be cultured into blastocysts. That is, embryos that form blastocysts are more likely to be successful after transfer.

Reason 3: Blastocyst transfer helps the uterus to receive the embryo.

Medical studies have found that the uterus contracts and spasms significantly on the day of egg retrieval. This symptom is very detrimental to the implanted embryo, as the embryo may be rejected. These symptoms may last for two to three days, then gradually lessen and largely disappear by the fourth or fifth day after egg retrieval.

Therefore, implantation of the blastocyst on day 5 of blastocyst culture gives the uterus enough time to recover so that the blastocyst can implant better.

Of course, not all embryos are suitable for cyst rearing, because blastocyst formation is risky, and the success of blastocyst rearing is closely related to the quantity and quality of embryos. Of course, if you have the opportunity to do blastocyst culture, you can still give it a try!

The success rate of IVF blastocyst transfer is relatively high, but there are many people who fail blastocyst transfer. Generally, the success rate is 40%, and the level varies from hospital to hospital.

The success rate of IVF blastocyst transfer can be said to have reached 50%. This is a good result.

In general, the chance of a natural pregnancy per month for a couple of normal childbearing age is no more than 20%. In layman's terms. That is to say, it is not something that every couple can easily get if they want a baby every month.

Similarly, "IVF" is not successful in every cycle. The success rate of IVF in the world is about 30%, and the overall success rate in China will be lower, but the success rate will be higher than 30% in a small number of mature and standardized centers.

IVF embryo transfer time, fertilized eggs in vitro culture for 48-72 hours can develop to 8 16-cell stage embryos. At present, embryos are transferred 2 to 3 days after fertilization, and the embryo transfer time is delayed, the higher the requirements for in vitro culture, but it is more in line with the physiology of pregnancy.

In view of the many uncertain risks associated with IVF, IVF technology should not be abused, let alone used as a means to have multiple births. For families who are unable to conceive naturally, they must choose a regular and qualified hospital for IVF, and strive to minimize the danger.

Factors influencing the success of embryo transfer.

1. The woman's age plays a vital role. Generally speaking, even if the man is fifty or sixty years old, the impact on fertility is not obvious, but it is not so good for the woman. As the woman ages, fertility declines gradually, accelerates significantly after the age of 35, and is completely lost after menopause, and this process is irreversible.

At present, there is no drug that can "rejuvenate" a woman's fertility.

2. Ovarian function refers to the responsiveness of the ovaries to ovulation induction drugs. The worse the ovarian function, the fewer eggs obtained and the worse the quality of the eggs, the lower the pregnancy rate and the higher the miscarriage rate. Ovarian function is related to differences between individuals, in addition to age.

3. Hydrosalpinx is also a serious cause of infertility, and if a patient with hydrosalpinx wishes to conceive a test-tube baby, the pregnancy rate is lower than that of a person without hydrosalpinx, and the incidence of miscarriage and ectopic pregnancy will be greatly increased. The literature shows that hydrosalpinx reduces the pregnancy rate and implantation rate of IVF by 50%, and increases the miscarriage rate by 2 times.

4. That is to say, if the success rate of IVF is 20% to 30%, if there is hydrosalpinx, the success rate will be 10% 15%, coupled with the increase in the miscarriage rate, so it is very important to say that before IVF, hydrosalpinx is very important.

It can be said that the technical nature of IVF to promote pregnancy has once again ignited the expectations of many infertile couples, so in the whole process of IVF, the doctor will generally choose to implant the embryo according to the blastocyst transfer. Today, let's talk to you about blastocyst transfer. Blastocyst transfer technology is more common in IVF, which belongs to an embryo transfer method, and the application of blastocyst transfer technology can not only improve the embryo implantation rate of IVF embryos, but also reduce the probability of fetal distress.

The first thing people want to explain is what is blastocyst transfer? The culture time is five days, and embryos with a total number of 100 somatic cells or more are called blastocysts. Blastocyst transfer technology is to transfer high-quality blastocyst embryos into the uterus of the pregnant mother, like artificial conception, without the influence of artificial services, the embryo is embedded into the pregnant mother according to the way of the blastocyst, which can achieve a higher embryo insertion rate.

Blastocyst technology can achieve a visual and reliable practical effect in distinguishing the quality of embryos, so that the fake and inferior defective embryos can be replaced in the whole process.

To put it bluntly, the general embryo transfer is to select embryos with a culture time of three days to carry out transplantation, and the embryos at this time grow and develop to 8 somatic cells. Compared with the blastocysts cultured for three days, it is obvious that there are some deficiencies in general embryos, such as the actual effect of visualizing the good and the bad, and then the fake and inferior embryos cannot be removed according to the method of artificial control, and the goal of eugenics cannot be achieved.

The previous people said what is called blastocyst transfer, so let's take a step to analyze what are the advantages of blastocyst transfer?

The first advantage is that blastocyst transfer allows for selective embryo transfer. Blastocyst transfer embryos are cultured outside the body for a longer period of time than fresh embryos, which can further replace defective embryos with no growth and development potential, and thus achieve the goal of selecting better quality embryos.

The second advantage is that it is more physiologically time-sensitive. The same is because the blastocyst must be cultured for a longer period of time, so it can be kept in the same condition as the uterine wall, which can not only greatly improve the clinical pregnancy rate and embryo planting rate, but also reduce the fetal distress rate under the condition of selecting high-quality blastocysts.

The third advantage is to ensure the pass rate of the embedding. We know that the blastocyst has to go through the process of removing the zona pellucida and can be immediately attached to the uterine membranes.

The fourth advantage is to reduce the harm of suboptimal elements when the embryo communicates with the pregnant mother. In the whole process of blastocyst transfer, it can be possible to reduce the time for the embryo to grow and develop again, so as to reduce the harm of suboptimal elements.

Another point is that the somatic cell extract of the blastocyst will be obtained from the laboratory for PGS PGD examination when doing the test tube, and the embryo will be transplanted into the uterus only when the test result is not problematic, which further increases the probability of embryo implantation.

Because it is easier to survive and the blastocyst is easier to survive, it is easier to succeed.

Because the technology is now more developed and the technology is more advanced, the possibility of IVF failure is reduced, and the success rate is improved.

Because such things are already maturing, the probability of survival is relatively high, and this has a certain relationship with development.

Because this kind of cultivation method is generally relatively healthy, it is also relatively safe, and it will not be affected by particularly serious external influences, and then the probability of success is relatively high.

It may be that the development of medical technology has improved the success rate of IVF, or it may be that the uterus is better protected.