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Chirality is usually for isomerism in organic chemistry.
Carbon atoms. When forming an organic molecule, 4 atoms or groups can pass through 4 covalent bonds.
A three-dimensional spatial structure is formed. Due to the different attached atoms or groups, it forms two molecular structures. These two molecules have exactly the same physical and chemical properties.
For example, their boiling points are the same, and so are their solubility and spectrum. But judging from the composition and shape of the molecules, they are still two molecules. This situation is like the objects inside and outside the mirror, which seem to correspond to each other.
Because they are three-dimensional, they don't coincide no matter how they are rotated, and if you look at your hand, you will see that your left hand and right hand look exactly the same, but no matter how you place them, they don't coincide exactly in space. If you put your left hand in front of the mirror, you will find that your right hand is really exactly the same as your left hand in the mirror, and your right hand and your left hand in the mirror can overlap exactly. Actually, your right hand is exactly what your left hand looks like in the mirror, and vice versa.
Therefore, it is also called chiral molecules.
Chiral molecules have different melting and boiling points due to their different physical properties, and they are all three-dimensional structures.
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The chiral molecule and its enantiomer (mirror image) belong to isomers, because the two are indeed not the same thing, and in physical properties, the optical rotation is opposite.
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Chiral molecules: Molecules with a certain configuration or conformation that are different from their mirror images and cannot coincide with each other. For example, sugars in nature and sugar units in nucleic acids, starches, and cellulose are all in d-configuration; The basic materials of all biological macromolecules on the earth—amino acids—the vast majority of which are in L- configuration; The helical conformation of proteins and DNA is right-handed; It was also found that the threads and winding plants of the conch were also right-handed.
Enantiomers: stereoisomers that cannot overlap with each other as physical objects and mirror images are called enantiomers, and enantiomers have optical rotation, one of which is left-handed and one is right-handed, so enantiomers are also called optical isomers.
There are three kinds of lactic acid with different **, lactic acid extracted from animal muscle, which is dextralator; lactic acid obtained by fermentation is levorotator; It is obtained by artificial synthesis and is racemate. There is an asymmetric carbon atom in the molecule, which has optical rotation, so there are two optical isomers of L-lactic acid and D-lactic acid.
Racemate: An isomolar mixture of a chiral molecule (see chiral isomerism) with optical rotation (see photoisomerism) and its enantiomers. Racemates are commonly labeled with D,L-.
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Chiral molecules. It refers to molecules with a certain configuration or conformation that are different from their mirror images and cannot coincide with each other. The stereoisomers that cannot overlap with each other as physical objects and mirror images are called enantiomers.
Enantiomer, simply known as enantiomers, enantiomers have optical rotation.
One of them is left-handed and the other is right-handed, so enantiomers are also called optical isomers.
A racemate is an equimolar mixture of chiral molecules (see chirality) with optical rotation (see photorotation isomerism) and their enantiomers.
Chiral drug refers to a class of drugs in which the three-dimensional structure of the molecule and its mirror image cannot coincide with each other, and a pair of drug structures that are mirror images of each other but cannot coincide are called enantiomers, and conversely, molecules or drugs with enantiomers are called chiral molecules or drugs.
Molecular chirality is usually caused by asymmetric carbon, that is, four different atoms or groups are attached to a carbon, so this "carbon" is often referred to as "chiral carbon atoms."
Figure 1: Sitagliptin.
For example).
In layman's terms, the enantiomers of chiral drugs are like the left and right hands of a person, which are enantiometers and cannot coincide (just as the right hand cannot wear left gloves; The left hand can not wear the right glove as shown in Figure 2), under general conditions, the physical properties of each enantiomer.
and the chemical properties are the same.
The difference is that their rotation direction is the opposite state clear ridge, which is expressed as levo-transosmotic ( ) dextro ( ) and racemic ( ) Because of this, the pharmacodynamics, pharmacokinetics and toxicology of chiral drug enantiomers.
There may be a big difference, some of the enantiomers have the best effect, while the other has no effect or little effect, or even poison.
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Question 1: How many isomers are there and what are they?
Question 2: What is the difference between isomers and their counterparts? 1.
Isomers refer to a class of substances with the same molecular formula but different structures (i.e., different arrangements of atoms), which are called isomers to each other. The number and position of the branched chains, the type and position of functional groups of isomers can be different. For example, 1-butanol, 2-butanol, 2-methyl-1-butanol and ether have the molecular formula of C4H10O, and they are isomers of each other.
2.Enantiomers are stereoisomers that are object and mirror images of each other, and are called enantiomers (enantiomers for short).The number of branches, the position, and the type of functional groups must be the same, but they are never completely consistent.
To put it simply, the relationship between two isomers is like the three-dimensional structure of an object looking in a mirror, and the three-dimensional structure and its image in the mirror are enantiomers of each other. Or take a look at your left and right hands! Contact:
Substances that are enantiomers of each other must be isomers, but isomers that are isomers of each other are not necessarily enantiomers.
Question 3: What is the change in the transformation between isomers Isomers are also known as isomers. In chemistry, it refers to molecules that have the same molecular formula; The chemical bonds between atoms are also often the same; But the arrangement of the atoms is different.
In other words, they have different "structural formulas". Many isomers have the same or similar chemical properties. The phenomenon of isomerism is one of the reasons for the large variety and quantity of organic compounds.
The composition and molecular weight of isomers are exactly the same, but the structure, physical properties and chemical properties of the molecules are different, and isomers are referred to as isomers.
Isomers in organic matter are divided into two categories: tectonic isomerism and stereoisomerism. Having the same molecular formula but having a different order of attachment of atoms or groups in a molecule is called tectonic isomerism. In molecules, atoms bind in the same order, but atoms or clusters of atoms differ in their relative positions in space, which is called stereoisomerism.
Tectonic isomerism is further divided into (carbon) chain isomerism, positional isomerism and functional group isomerism (heteroisomerism). Stereoisomerism is further divided into conformational and configuration isomerism, and configuration isomerism is also divided into cis-trans isomerism and optical rotation isomerism (also known as enantiosterism).
Question 4: What is the isomer of the amyl group?
Question 5: What is the difference between isomers and allotropes? Isomeric II is the name given in organic compounds.
Allotropes are the term used in inorganic compounds to refer to different forms of the same element (such as oxygen and ozone).
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Chiral molecules are molecules in chemistry that are structurally mirror-symmetrical but cannot be completely coincidental. When carbon atoms form organic molecules, 4 atoms or groups can form a three-dimensional spatial structure through 4 covalent bonds. Stereoisomers that are object and mirror images are called enantiomers (enantiomers for short).
Enantiomers all have optical rotation, one of which is left-handed and one is right-handed. It is also known as optical isomerism.
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In organic chemistry, compounds with the same molecular formula and different structures are called isomers with each other, also known as structural isomers. The phenomenon of having the same molecular formula but different structures is called isomerism.
Isomers are also known as isomers. In chemistry, it refers to molecules with the same molecular formula, and the chemical bonds between atoms are often the same; But the arrangement of the atoms is different. In other words, they have different "structural formulas".
Many isomers have the same or similar chemical properties, but if they are isomers of functional groups (i.e., functional groups are different), then the chemical properties are different because the chemical properties of organic matter are mainly determined by functional groups. For example, C2H5OH and CH3OCH3. If it is an isomer of carbon chain isomerism and positional isomerism, then the chemical properties are similar.
The phenomenon of isomerism is one of the reasons for the large variety and quantity of organic compounds.
The essence of isomers produced by organic matter lies in the different order of atoms, which mainly refers to the following three situations in secondary school:
Carbon chain isomerism: isomerism caused by different attachment orders of carbon atoms, such as ch3ch(ch3)ch3 and ch3ch2ch2ch3.
Functional group position isomerism: Isomerism caused by the different positions of functional groups, such as: ch3ch2ch=ch2 and ch3ch=chch3.
Heterogeneous isomerism of functional groups: The isomeric phenomena caused by the difference of functional groups mainly include:
Monoolefins and naphthenes: the general formula is CNH2N(N 1).
Diolefins, monoalkynes and cyclomonoolefins: the general formula is CNH2N-2(N3).
Benzene and its homologues and polyenes: the general formula is CNH2N-6(N6).
Saturated monools and saturated monoethers: the general formula is CNH2N+2O(N2).
Saturated monoaldehyde, saturated monoketo, enol: the general formula is CNH2NO(N3).
Saturated monocarboxylic acids, saturated monoesters, hydroxyaldehydes: the general formula is CNH2NO2(N2).
Phenol, aromatic alcohol, aromatic ether: the general formula is CNH2N-6O(N6).
glucose and fructose; Sucrose vs. maltose.
Amino acids [R-CH(NH2)-COOH] vs. nitro compounds (R'-NO2).
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Substances with the same molecular formula but different structures are like you can build different shapes with the same building blocks.
Isomers are particularly common in organic chemistry, and are mainly classified into structural isomerism (including carbon frame isomerism, functional group isomerism, tautomerism, position isomerism, valence bond isomerism, etc.) and stereoisomerism (including configuration isomerism, such as cis-trans isomerism, optical rotation isomerism, etc., and conformational isomerism). Of course, there are some other isomeric phenomena, such as one that will be encountered in aromatic hydrocarbons and derivatives, called electron tautomers, etc., which belong to the category of isomers.
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Isomers in organic chemistry refer to several substances that have the same molecular formula but different atomic arrangements.
These substances are isomers of each other.
For example, the chemical formula C3H6 can represent propylene and cyclopropane, so the two of them are isomers of each other.
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Summary. Hello dear, glad to answer for you! Chiral molecules are all optically opticapulatory, and there must be a pair of corresponding isomers, which can be split.
Hello dear, glad to answer for you! Chiral molecules are all optically opticapulatory, and there must be a pair of corresponding isomers, which can be split.
Isomers generally refer to isomers. In organic chemistry, compounds with the same molecular formula and different knotting high index structures are called isomers, also known as structural isomers. Phenomena with the same molecular formula but different structures are called isomerism.
Chemically, an isomer is a compound with the same chemical formula, the same chemical bond, and a different arrangement of atoms.
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Chiral molecules: Molecules that cannot overlap their mirror images.
Chiral carbon atoms: Carbon atoms with 4 different atoms or groups are called asymmetric carbon atoms, also known as chiral carbon atoms.
Methods for judging enantiomers:
1. Method 1: The most direct method is to build a model of a molecule and its mirror image, compare the structure of the two, if the two cannot coincide, then the molecule has an enantiomer. Conversely, the molecule has no enantiomers.
2. Method 2: Find the symmetry plane or symmetry center of the target molecule, if the molecule has a symmetry plane or symmetry center, usually the molecule is an achiral molecule, no optical rotation, and no enantiomer.
3. Method 3: Find the chiral carbon atom or chiral center in the target molecule, if there is a chiral carbon atom in the target molecule, the molecule is chiral and has a pair of enantiomers. If there are two or more chiral carbon atoms in the target molecule, the chirality needs to be analyzed on a structure-by-structure basis, with possible exceptions.
For example, in racemic compounds, there are several chiral carbons with the same structure in the molecule, but the configuration is opposite, so that the molecule as a whole does not have optical rotation.
It seems that you are also high in life.
Chemically, an isomer is a compound with the same chemical formula, the same chemical bond, and a different arrangement of atoms. To put it simply, the phenomenon that compounds have the same molecular formula but have different structures is called isomerism; Compounds with the same molecular formula but different structures are isomers of each other. Many isomers have similar properties. >>>More
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