Consult the treatment of signet ring cell carcinoma

The degree of malignancy is very high.

Is it still ovarian cancer?

It should be applied to the digestive tract.

Is there still a possibility of **?

In pathology, the cells are filled with a large amount of mucus, so that the nucleus is squeezed to one side, looking like a ring, called signet ring cell carcinoma, which is more malignant than mucinous adenocarcinoma (mucus between cells, forming a mucus lake), and has a worse prognosis among all types of gastric cancer.

But this is only relative, like this patient, after the ** resection of gastric cancer (there are 25 lymph nodes, indicating that the dissection is very thorough), the postoperative stage is stage, and adjuvant chemotherapy must be performed after surgery to remove the small tumor foci that cannot be seen by the naked eye and prolong the survival rate. Chemotherapy is generally a combination of 5 fu and platinum as the first-line chemotherapy regimen. Usually six rounds of chemotherapy are given.

It is necessary to firmly believe in the three pillars of oncology**: surgery, radiotherapy, and chemotherapy. Traditional Chinese medicine only plays a role in conditioning aid.

Chemotherapy is followed by surgery, and further ** is decided after surgery according to the pathological condition (chemotherapy may still need to be continued for about 6 courses).

If the above ** can be completed by the patient in turn, it is already the best ** means.

As for the ** rate, based on the patient's current tumor range is relatively large and relatively advanced, it should be said that the ** rate is very low, and there is no possibility of **.

It is suggested that netizens should have a correct understanding of the patient's current disease and avoid blind non-scientific means.

As for the most accurate diagnosis of the patient, it is better to wait for the end of the operation, and all diagnostic questions will be solved at that time.

Analysis:

Hello friends, Signet ring cell carcinoma, also known as mucinous adenocarcinoma, is highly malignant like a ring.

Guidance: This kind of cancer cancer cells are like rings, commonly known as signet ring cell carcinoma, this kind of cancer cells have poor differentiation, high mortality, and easy metastasis, so surgery or conservative ** should be appropriately selected according to the patient's condition. Reflux esophagitis is usually the result of a combination of refluxed bile and stomach acid acting on the esophageal mucosa, which was caused by a stomach tumor before bile caused esophageal damage. Now this situation can only be conservative ** better, I wish you a healthy and happy Spring Festival.

The doctor asked: Did you have surgery?

Hello, combined with the patient's condition, it is signet ring cell carcinoma disease, which is a high-grade malignant tumor disease, which is generally asymptomatic if mild, and can cause discomfort symptoms such as pain in severe cases.

For patients, a comprehensive examination is required, surgery is required if there is no metastasis, chemotherapy is required**, and intraperitoneal hyperthermic chemotherapy is required if there is intraperitoneal lymph node metastasis in the postoperative pathology**.

1.Gastric signet ring cell carcinoma.

Gastric signet ring cell carcinoma is a kind of low-grade adenocarcinoma with high malignancy, which is prone to diffuse and invasive growth in the stomach wall, with strong aggressiveness and high metastasis rate, and is often not detected until an advanced stage. Signet ring cell carcinoma is a specific type of stomach cancer that contains a lot of mucus. Early gastric signet ring cell carcinoma mostly occurs in young women, and the general type is mainly depressed type, and the proportion of intramucosal carcinoma is more, and its prognosis is significantly better than that of non-signet ring cell carcinoma.

2.Signet ring cell carcinoma of the breast.

Primary signet ring cell carcinoma of the breast is invasive breast cancer that is composed primarily or entirely of signet ring cells, which contain intracytoplasmic mucus. Simple signet ring cell carcinoma is rarer. There are two types of signet ring cell carcinoma, one is associated with lobular carcinoma, which is similar to the classic invasive lobular carcinoma, with large vacuoles visible in the cytoplasm, often eosinophilic globules in the vacuoles, and the nucleus is pressed on one side.

The other is associated with ductal carcinoma and is morphologically similar to gastric signet ring cell carcinoma, with a nucleus on one side, a cytoplasm filled with eosinophilic mucus material, and signet ring cells in solid or cribriform ductal carcinomas. Signet ring cell carcinoma has a high aggressive, metastatic propensity and a poor prognosis.

3.Bladder signet ring cell carcinoma.

Signet ring cell carcinoma of the bladder, that is, primary signet ring cell carcinoma of the bladder, was first described by Saphir in 1955 and is extremely rare in clinical practice, accounting for 1 4 of all bladder malignant tumors, more common in men and more common in middle-aged and elderly people.

4.Prostate signet ring cell carcinoma.

Primary prostatic signet ring cell carcinoma is highly aggressive, metastasizes rapidly, involves various organs outside the prostate, and is diagnosed early, early and comprehensive, which may improve the long-term survival rate.

5.Pancreatic signet ring cell carcinoma.

Pancreatic signet ring cell carcinoma is a less common subtype of pancreatic cancer with a high degree of malignancy. Histologically, tumor cells are diffusely distributed, round, cytoplasmically rich and mucus-filled, and the nucleus is squeezed on the cytoplasmic side in a "sign-ring" shape. Needle aspiration cytology is similar to histology, with cells scattered or loosely adhered into clumps, round, mucous vacuole-like cytoplasm, hyperchromatic nuclei, round or squeezed in a crescent shape.

Mucus staining is positive, and PAS staining is weakly positive. Signet ring cells should be distinguished from macrophages that engulf mucus or lipids.

Hello, signet ring cell carcinoma is one of the high-grade malignant tumors. It has the characteristics of strong invasiveness, rapid progression of the course of the disease, and high degree of malignancy, and the natural course of the disease is only 3 to 6 months. Surgery and chemotherapy and radiotherapy cannot achieve satisfactory results, and it may increase the pain of the disease, consume physical strength, and accelerate the deterioration of the disease.

It should be learned (sunshine life Tang Junhua) to improve.

It has a certain relationship with your own physical condition. If you are in good health and can tolerate chemotherapy, you will be treated with chemotherapy. If the general situation is poor, you can only do support**. At this time, you can find more experience and feelings through learning (Tang Junhua Stomach Cancer Sunshine Life).

Signet ring cell carcinoma is mostly insensitive to chemotherapy, and the current surgery is still the first vertigo, but it can only be used for cases that have not spread, and early diagnosis and early surgery can be achieved to achieve a certain effect. Most advanced signet ring cancer does not advocate surgery**, but adopts a comprehensive ** based on internal medicine, which is more successful because there is a lot of experience in the process of fighting cancer, which can be referred to.

Signet-ring cell carcinoma: Also known as mucinous cell carcinoma. It is a type of cancer cell that contains a lot of mucus, and it gets its name because the cell is filled with mucus that squeezes the nucleus to one side of the cell, making it look like a ring.

Gastric signet ring cell carcinoma is one of the more difficult cancers, gastric signet ring cell carcinoma, its replication and metastasis are relatively fast, targeted drugs have limitations on its effect, but generally very early, early signet ring cell carcinoma, the control is still relatively good, the survival rate of early signet ring cell carcinoma patients and advanced patients is very different, so early detection is very important.

Patients in the early stages generally have a better prognosis after surgical resection. Patients with intermediate and advanced stages should undergo a surgery-based synthesis**.

Signet ring cell carcinoma (SRC) is a highly malignant mucin-secreting adenocarcinoma that originates in the mucosal epithelium, in which the cancer cells produce mucin. The cytoplasm is filled with mucus, squeezes the nucleus on one side of the cytoplasm, and is named after the microscopic appearance of a "sign-ring-like" appearance, and 90% of patients with SRCC originate in the gastrointestinal tract and, less commonly, in the breast, gallbladder, bladder, and pancreas. Masses are generally diffuse, infiltrative, and tend to metastasize, and most people are in the middle and late stages when they are discovered.

Patients in the early stages generally have a better prognosis after surgical resection. Patients with intermediate and advanced stages should undergo a surgery-based synthesis**. Diagnosis remains based on histopathological examination.

Signet ring cell carcinoma has the worst prognosis!

Unfortunately, gastric signet ring cell carcinoma is a relatively malignant gastric tumor with early metastasis, so there is no special good way to treat advanced gastric signet ring cell carcinoma.

Gastric signet ring cell carcinoma has metastasis of varying degrees in advanced stages, so surgery is not supported. Gastric signet ring cell carcinoma is also less sensitive to remorse, but chemotherapy can be given if the body is in good condition and can tolerate chemotherapy. If the general situation is not good, you can only do support**.

If you are diagnosed with advanced gastric signet ring cell carcinoma, you can try some new drugs that have emerged in recent years, such as paclitaxel, platinum oxalate or heroda. If combined with traditional Chinese medicine** and hyperthermia, the effect will be better. But this can also be said to be only an expectation of prolonging life.

Now the most important thing is the remaining quality of survival, it is best to hide the severity of the patient's condition, use the examples of other cancer patients to give confidence, maintain a good attitude, pay attention to rest and nutrition, it is expected to prolong their survival and improve the quality of their survival.

Maybe mine won't help you much (and it should be what you expected), but I can only tell the truth like this, I'm sorry, and I'm helpless.

Supplement: Surgery is generally not recommended for this type of advanced cancer, not to mention the elderly, the results of surgery are generally not very satisfactory, and most patients will have an impact on the quality of life of the remaining survival period after surgery. Therefore, please consider carefully whether or not to have surgery.