What are the symptoms of demyelination? Will there be limb weakness?

Demyelinating disease is a kind of acute onset or subacute damage to the nerve center and peripheral white matter of the immune disease, spinal cord symptoms are severe, the brain is seen in chronic subacute lesions damage the nerve resulting in dysfunction after magnetic resonance can be found, combined with optic nerve involvement called neuromyelitis optica or neuroencephalomyelitis optica, if the delay of the damaged nerve secondary ischemic degeneration will occur, multiple sclerosis will occur, if the demyelination damages the motor nerve, there will be limb dysfunction. And when the disease is severe, it can invade the anterior horn cells of the spinal cord and the nerve nucleus of the brainstem and the pyramidal cells of the cerebral motor cortex, and if it occurs in the peripheral nerves, regional dysfunction will mostly occur, and the disease is mostly caused by abnormal genetic immunity or viral infection, trauma and hypoxia. In the early stage, most of them were hormones and nutrition, but the curative effect was difficult to control and the recovery was false, and the hormone stopped was more likely to be **.

Due to the loss of myelin caused by this disease, neurological damage is caused by severe secondary axonal damage, which further aggravates neurological symptoms, and delays the onset of sclerosis and necrosis of the entire central nervous system, resulting in spastic paralysis and life-threatening

Demyelination can significantly reduce the body's own vision or lead to blindness. Subjective feeling of body cold, weakness in limbs, and backache will cause a series of diseases to the body. The occurrence of demyelination phenomenon mainly affects adolescents, and after vaccination, due to the occurrence of demyelination caused by poor maintenance after vaccination, the adolescent's body may be found to be hemiplegia, or the body cannot move in a large area resulting in paralysis.

And it can also cause memory loss in adolescents, and the functions of the kidneys and other functions are sharply weakened. Once you find that you are unwell and have abnormal multi-functional phenomena, you must go to the hospital in time. The onset of demyelination is rapid, and your own state is getting worse and worse, so you must not self-medicate at home, and you must follow the doctor's instructions to cooperate**.

Demyelination occurs when the myelin sheath of the axons of the cerebrospinal cord is lost. There are two categories: myelin destruction; Disorders of myelination. Spinal inflammatory demyelinating diseases are currently considered to be immune-mediated diseases, and their clinical features are:

The patients were children and young adults;

Acute onset, common history of cold, fever, infection, rash, vaccination, cold, childbirth or surgery 1 month before the illness;

A thorough neurological examination often reveals evidence of other central nervous system involvement in addition to spinal cord symptoms and signs;

cerebrospinal fluid examination is positive for oligoclonal bands;

Electrophysiology and MRI can detect some subclinical lesions in the brain; MRI reveals abnormal signals of white matter in the brain. Some myelittic demyelinating lesions present:"Pseudoneoplasia"Manifestations, the MRI shows a mild mass effect, mild edema around it, and there may be patchy hemorrhagic signals, which can easily be misdiagnosed as spinal cord tumors. At present, the effect of internal medicine drugs** is not good.

Therefore, neurosurgical intervention is inevitable and necessary.

Demyelinating myelitis is usually acute multiple sclerosis (MS) spinal type, and the clinical presentation is similar to that of postinfectious myelitis, but the progression is slow, and the disease usually peaks within 1 to 3 weeks. The prodromal infection may be subtle, usually incomplete transverse lesions, with weakness or paralysis of one or both lower extremities, with numbness, the level of sensory impairment is inconspicuous or two-plane, and urinary and fecal disorders are present. Evoked potentials and MRI may reveal lesions elsewhere in the CNS.

The most common symptoms of demyelinating diseases are: decreased vision, muscle weakness, muscle stiffness, muscle spasms, changes in the function of the bladder and bowel, and decreased vision. Muscle weakness. Muscle stiffness. Muscle spasms. Changes in the function of the bladder and bowel.

Demyelination is mainly manifested by weakness of limbs, paresthesia, and some patients will have symptoms such as decreased vision, slurred speech, and tonic spasm. There will even be some patients with movement disorders, sphincter disorders, mental disorders and other symptoms

What are the early symptoms of demyelination?

Demyelinating disease refers to any disease in which the myelin sheath is damaged. When the myelin sheath is damaged, scar tissue forms. Since brain signals cannot travel quickly through the scar tissue, in this case, the patient's nerves cannot work properly and effectively, just as the outer skin of a wire is torn off and the wire does not work properly.

Early symptoms are as follows:

1) Limb weakness is the most common, and about 50% of patients have one or more limb weakness as the first symptom.

2) Paresthesia is manifested as numbness in the limbs, trunk or face, chills in the limbs, ant walking sensation, etc.

3) Ocular symptoms: acute monocular vision loss, ophthalmoplegia.

4) nystagmus, intention tremor, and poetic language may be seen in some patients.

5) Episodic symptoms that are short-lived and can be induced by special factors in sensory or motor abnormalities.

6) Psychiatric symptoms are mostly manifested as depression, irritability and short temper.

7) Other symptoms include bladder dysfunction, sexual dysfunction in male patients, etc.

The above content is a brief introduction to "what are the early symptoms of demyelination", I believe everyone has a certain understanding. Demyelination is a disease that is currently more harmful to the body, for the sake of our health, we must pay attention to it, pay attention to the early symptoms, and actively prevent and treat it when it is found.

Multiple sclerosis: weakness in walking on all fours, fatigue, and difficulty moving. Patients have numbness in the limbs, trunk, or face, cold limbs with ant walking, numbness of the ophthalmic muscles, and nystagmus in some patients.

Acute disseminated encephalomyelitis: patients may present with high fever accompanied by headache, fatigue, and body aches.

Acute inflammatory demyelinating polyneuropathy: most patients have symptoms of respiratory or gastrointestinal infection with symmetrical weakness of the distal extremities that quickly worsen and progress proximally.

Chronic inflammatory demyelinating polyneuropathy: hypodexteria, decreased muscle tone, and peripheral hypoesthesia of the extremities may be seen on physical examination.

Demyelination is divided into white matter demyelination, ischemic demyelination, neuromyelitis optica, multiple sclerosis, etc.

Multiple sclerosis.

Multiple sclerosis is a type of central system demyelinating disorder, which is classified as secondary demyelination. It will be due to viral infection, and it will also be due to other reasons, such as low immunity, genetic factors, environmental factors, etc.

The clinical manifestations of multiple sclerosis mainly include limb weakness, numbness of hands and feet, inconvenience, cramps, which will bring physical disability to patients, and some patients may have autonomic dysfunction, incontinence, constipation, etc.

Neuromyelitis optica.

The symptoms of neuromyelitis optica include decreased vision, eye pain, double vision, numbness and pain in the limbs, tingling sensation, ant crawling sensation, dizziness, ataxia and other clinical manifestations. Neuromyelitis optica can lead to multiple sclerosis, and the disease is relatively serious.

Demyelination is divided into central nervous system demyelination and peripheral nerve demyelination, and is also divided into chronic demyelination and acute demyelination, and the damage site and symptoms of the two are also different.

Multiple sclerosis is an acute demyelination of the central nervous system caused by immune disorders, and the symptoms are dysarthria, visual field may be affected, or sensory loss, and some patients will manifest themselves with limb mobility impairment and paralysis, or even symptoms of urination disorders, or patients may manifest as agitation, forced crying, forced laughter, and decreased memory.

The symptoms of patients with chronic central demyelination may be manifested as chronic headache, dizziness and heaviness, etc., obvious positive signs are unlikely to appear, it is recommended that patients go to the hospital in time, actively cooperate with the standard, and the recovery effect is still ideal.