What are the specific symptoms of white matter demyelination?

The symptoms of white matter demyelination vary according to the severity of the disease and are mainly divided into the following conditions:

1. The condition is mild: the main symptoms are dizziness and headache, lack of concentration, easy fatigue, uncoordinated limbs, slight loss of vision in some patients, arteriosclerosis in middle-aged and elderly patients, and demyelinating lesions can be observed in imaging examinations;

2. Severe disease: pathological phenomena can occur, mainly manifested as numbness of limbs, significant loss of unilateral or bilateral vision, decreased body coordination, unsteady walking, and some patients have high fever, fatigue and weakness of legs and limbs, and urine and urine disorders.

Early phenomena: The general early phenomena are: dizziness, headache, low immunity such as fever and cold that do not go away for a long time. Walking is not fast, loss of balance, generally this term is a term for early symptoms that are symptomatic but not obvious, and can lead a normal life.

Medium-term phenomenon: Medium-term phenomenon means that one or two seizures have been experienced. For example:

Urinary retention, incontinence, hypertonia of the lower limbs, functional impairment of peripheral nerve paralysis, memory loss, blurred strength, and confusion. This kind of just entering the lesion period is often used hormones, immunoglobulin**, this kind of can also be turned into a prognosis instrument, mainly Chinese medicine, the best effect.

Late stage phenomenon: Generally, patients in the advanced stage are very painful, mainly due to mental pressure. For example, coma, loss of consciousness, dementia, paralysis, etc., are often acute lesions caused by long-term lesions or poor physical fitness.

In the face of this situation, it is basically impossible to **, the speed of lesion incursion is disproportionate to the speed of drug absorption, that is to say, the repair speed of the drug cannot keep up with the destruction of the lesion, so it cannot be **.

The main symptoms of herniation are the inability to perform the activities of the mobility partner and the willpower, or the feeling of vision loss.

Demyelination occurs when the myelin sheath of the axons of the cerebrospinal cord is lost. There are two categories: myelin destruction; Disorders of myelination. Spinal inflammatory demyelinating diseases are currently considered to be immune-mediated diseases, and their clinical features are:

The patients were children and young adults;

Acute onset, common history of cold, fever, infection, rash, vaccination, cold, childbirth or surgery 1 month before the illness;

A thorough neurological examination often reveals evidence of other central nervous system involvement in addition to spinal cord symptoms and signs;

cerebrospinal fluid examination is positive for oligoclonal bands;

Electrophysiology and MRI can detect some subclinical lesions in the brain; MRI reveals abnormal signals of white matter in the brain. Some myelittic demyelinating lesions present:"Pseudoneoplasia"Manifestations, the MRI shows a mild mass effect, mild edema around it, and there may be patchy hemorrhagic signals, which can easily be misdiagnosed as spinal cord tumors. At present, the effect of internal medicine drugs** is not good.

Therefore, neurosurgical intervention is inevitable and necessary.

Demyelinating myelitis is usually acute multiple sclerosis (MS) spinal type, and the clinical presentation is similar to that of postinfectious myelitis, but the progression is slow, and the disease usually peaks within 1 to 3 weeks. The prodromal infection may be subtle, usually incomplete transverse lesions, with weakness or paralysis of one or both lower extremities, with numbness, the level of sensory impairment is inconspicuous or two-plane, and urinary and fecal disorders are present. Evoked potentials and MRI may reveal lesions elsewhere in the CNS.

The white matter of the brain is demyelinated, and the normal myelin that has matured is destroyed, and it can be a secondary manifestation of neurological diseases such as infection, poisoning, degeneration, post-trauma, infarction, deficiency, etc. Demyelination of the white matter mainly includes: multiple sclerosis, progressive multifocal leukoencephalopathy, acute sporadic encephalomyelitis, subacute sclerosing panencephalitis, pontine myelinolysis, corpus callosum degeneration, subcortical arteriosclerotic encephalopathy and concentric circle sclerosis.

There is a group of demyelinating diseases of the central nervous system whose causes are still unknown. At present, they are divided into two categories according to whether they are mature or not at the time of onset: demyelinating diseases with normal myelin development, such as multiple sclerosis, progressive multifocal leukoencephalopathy, acute sporadic encephalomyelitis, etc.; Myelinogenic diseases, such as spheroid cell leukodystrophy, metachromatic leukodystrophy, spongiform encephalopathy, etc. Genus.

Demyelination of the white matter is a neurological lesion that causes changes in the structure of nerve cells due to various reasons, and then produces dysfunction, which may be related to viral infection, genetic factors, and environmental factors.

Demyelination of the white matter is one of the lesions of the nervous system, which may be caused by the disorder of the immune system, which leads to inflammation of nerve cells, and the destruction of the myelin sheath, the outer structure of nerve cells; It may also be a congenital developmental abnormality, resulting in incomplete myelin sheath of nerve cells, causing nerve cell dysfunction, and patients often have limb weakness, paresthesias, decreased vision, decreased sense of balance, mental abnormalities and other manifestations.

A variety of reasons may be related to the demyelinating changes of the white matter of the brain, 1) Viral infection and autoimmune reactions: Epstein-Barr virus, herpes virus, measles virus, etc. may induce autoimmune reactions, resulting in this disease.

2) Genetic factors: Studies have shown that there is a certain relationship between this disease and genetics. If one parent has the disease, the risk of the child increases.

3) Environmental factors: Lack of sunlight and vitamin D deficiency can increase the risk of this disease.

White matter demyelinating lesions refer to a group of diseases that occur in the brain with myelin loss as the main feature, and neuronal cell bodies and axons are relatively mildly affected. It is usually caused by the premature decline of the patient due to social, family, work, life, etc.

The clinical manifestations of different patients are also different, and most patients present with clinical manifestations such as unresponsiveness, slow movement, memory loss, and neurological decline.

Some patients may have limb weakness or paralysis, slurred speech, urinary incontinence and other symptoms similar to cerebral infarction and cerebral hemorrhage. In severe cases, convulsions, confusion, coma may occur.

There are also some patients with localized white matter demyelinating lesions who do not have any symptoms, usually by incidental MRI.

Nerve fibers surround a membrane, which is called the myelin sheath, which is a metaphor for "the skin of the wire on the outside of the wire". Demyelination indicates that the myelin sheath is incomplete and there is a phenomenon of detachment. It is often seen in chronic intracranial ischemia, which is more common in the elderly, and can cause memory and cognitive function decline, and the incidence of cerebral infarction is extremely high.

There are also patients with unexplained demyelination, and in recent years, there has been "neoplastic demyelinating disease", which is often misdiagnosed as a tumor.

The demyelination of the white matter is mainly caused by damage to the autonomic nerves of the white matter of the brain and the dysregulation of the white matter, so that it cannot regulate itself autonomously and nourish the tissues of the innervation area.

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There are genetic factors and acquired factors.

Thus, demyelination is generally a condition in which the myelin sheath is destroyed, while axons are relatively detailed. As a result, there will be dizziness, general weakness and numbness!

The dangers of hormonal treatment of demyelinating lesions.

Western medicine commonly used hormones, immunosuppressants and various neurotrophic factors for demyelinating lesions, etc., its efficacy is limited to controlling symptoms, and the toxic adverse reactions are large, and the effect is not good. At present, there is no special scientific targeted means and drugs for demyelinating lesions in Western medicine. Compared with Western medicine, TCM** demyelinating lesions have their own advantages, which have been widely recognized and accepted by the majority of patients.

The main symptoms of white matter demyelination are as follows:

1. It will cause patients to have symptoms such as memory loss, slow thinking, and unsteady standing.

2. It will also cause patients to have frequent urination, urgency, difficulty swallowing, quadriplegia and other conditions.

3. If it is not timely, it may also cause patients to have physical diseases such as aspiration pneumonia and deep vein thrombosis.

Therefore, if the patient has memory loss and many of the above symptoms, it is necessary to go to the hospital for relevant examinations in time.