What is the mechanism of antibody production in the human body?

The antibody in our body is an immunoglobulin that is secreted by immune cells and can bind to anti-alpha and is one of the most important immune substances produced in our body's immune process. So how does the body produce this specific immunoglobulin? When the antigen breaks through the two lines of defense and enters our body, a small number of antibodies will directly bind to the antigen receptor on the surface of B cells. Most of the antigens cannot be directly recognized by B cells, but are found by a type of cell called antigen-presenting cells after entering the body, and the antigen information is presented to helper T cells (Th cells) after being activated, and the antigen information is provided to B cells after the Th cells are activated

B cells are activated to form plasma cells that secrete antibodies. At the same time, a subset of B cells will form memory cells, and when the same antigen invades for the second time, the memory cells will quickly form new plasma cells and produce antibodies to destroy the antigen. The antibodies produced by our body can be divided into five categories, which are IgM, IgG, IgA, IgE, and IgD.

IgM is the first antibody secreted in the immune response; IgG lasts for a long time, it activates complement, neutralizes toxins, and is the only antibody that can enter the fetus from the mother through the placental barrier; IgA mainly enters the mucous membranes of the respiratory tract and digestive tract to neutralize infectious agents, and it is also the most abundant antibody in breast milk; IgE can bind to mast cells and basophils, and the antibody that triggers an immediate allergic reaction is IGE; The role of IgD has not been further confirmed and may be related to the differentiation of B cells. Antibodies produced by B cells play an important role in the entire immune response of our body. <>

To put it simply, it is the rearrangement of the VDJ gene in the B cell, and then in the bone marrow, if it is judged that it will not accidentally injure one's own person, it will be put into the secondary immune organ, if it will be injured by mistake, then give the next chance to correct it, and if it is not changed, it will be shot directly. In this way, the antibodies that go out will not accidentally hurt their own people, and then they will come into contact with antigens, B cells will mature, and the antibody genes will be mutated by the AIDS enzyme, and then the affinity will be improved, and the lower ones will be hung up, and the cycle will be ......This is the process of antibodies and evolution. Antibodies exist only with antigens, and the renewal of antibodies also depends on contact with antigens.

The existing antibodies in your body are no longer regulated by your genes. How can your genes automatically mutate to produce antibodies before you are exposed to a new antigen? Parents, to be precise, mothers, transfer some of their antibodies to their offspring during periods such as pregnancy and breastfeeding, so that they can pass the period just after giving birth.

Antibodies are immunoglobulins that specifically bind to a specific antigen (epitope) for a certain antigen. Simple understanding: if you have antibodies to a certain drug, then your body can resist that drug and make the drug ineffective, such as for a certain virus, when the virus invades your body, your body's antibodies will destroy the virus, so that you will not get sick.

Antibodies are large Y-shaped proteins secreted by plasma cells (effector B cells) and used by the immune system to identify and neutralize foreign substances such as bacteria and viruses. Antibodies recognize a unique feature of a specific foreign object, which is called an antigen.

1 Effector T Cells Effector T cells (both are effector T cells)2 The role of antibodies is to specifically destroy antigens, 6, antibodies produced during humoral immunity in the body.

Immune system internal environment.

Pls 1If it indicates the immunocompetent cells produced during the immunization process, then it is () that the immune cell is able to cause the host cell infected by the pathogen to swim and lyse and die.

2. If it indicates the antibodies produced during humoral immunity, then their role in the body is ().

The production of antibodies is the body's various immunizations.

Cells work together to develop immune functions (defense functions) to prevent viruses and microorganisms from invading the human body, but of course the defense function is certain, not absolute. For example, vaccination is based on the function of the human immune system to prevent diseases. Vaccination is to reduce the virulence of a certain disease virus, inject into the human body, because the human body can recognize these foreign invaders, the human immune system begins to play a role, immune cells secrete some substances to kill these viruses, these substances secreted are antibodies, the next time the same virus invades, these immune systems have memory, like the first encounter with the virus to play a defensive function, so as not to prevent the disease, vaccination is to prevent a disease.

Of course, there are some diseases that the immune system cannot prevent such as cancer, but in fact, various viruses invade the human body every day, and we are not uncomfortable, it is our body's own immune system that is playing a role.