What causes Parkinson s disease?

Symptoms of Parkinson's disease are caused by decreased levels of the neurotransmitter dopamine in the brain's substantia nigrastriatal system. Dopamine levels decrease when the nerve cells in the brain that produce dopamine decline. But the exact cause of the decline of these nerve cells is unknown.

Scientists are trying to find a link between Parkinson's disease and genetics, aging, toxic substances in the environment, and oxidative free radicals, but the exact cause has not yet been found.

What are the risk factors for Parkinson's disease?

Risk factors for Parkinson's disease are also difficult to identify because they are unclear.

Here are some of the risk factors that may be associated with Parkinson's disease:

Aging. Older age is the only known risk factor for classic Parkinson's disease. Most Parkinson's diseases occur after age 50.

Family history. Family history of classic Parkinson's disease is not obvious. A family history of Parkinson's disease is an important risk factor for early-onset Parkinson's disease, but early-onset Parkinson's disease is uncommon.

Environments where toxic substances are present. Some studies suggest that long-term exposure to toxic substances such as pesticides and chemicals may increase the risk of Parkinson's disease.

The common Parkinson's disease is a very terrible disease for the elderly, because if the condition of Parkinson's disease is not effective, it will lead to the continuous deterioration of the condition, and the patient's friends will lose the ability to take care of themselves.

1. Brain disease: This factor leads to the occurrence of Parkinson's disease, mainly because it leads to multiple lacunar cerebral infarctions in the brainstem and basal ganglia, which affects the substantia nigra dopamine striatal pathway. However, such patients are often accompanied by pseudobulbar palsy, hyperreflexia, positive pathology, and often combined with obvious dementia.

2. Infectious factors: Generally, patients with encephalitis will develop Parkinson's disease syndrome, such as A encephalitis, which has an incubation period of several years after recovery, and gradually develops severe and long-lasting Parkinson's disease syndrome.

3. Drug factors: If you take antipsychotic drugs for a long time in your life, such as phenothiazines and butyryl drugs, you may have symptoms similar to Parkinson's disease, which can disappear completely after stopping the drug.

The ** that caused Parkinson's is not clear for the time being. Current research tends to be related to a combination of factors such as aging, genetic predisposition, and exposure to environmental toxins. Environmental factors:

Epidemiological findings have found regional differences in the prevalence of Parkinson's disease, so there is a suspicion that there may be some toxic substances in the environment that damage neurons in the brain. Familial hereditary: In long-term practice, medical scientists have found that Parkinson's disease seems to have a tendency to cluster in families, and the incidence of Parkinson's disease in relatives is higher than that of the normal population.

Parkinson's disease is a disease caused by autonomic nervous system dysfunction, and the elderly are generally prone to this type of Parkinson's disease when they go through menopause.

At present, it is not very clear whether there is any special and effective ** method, some drugs can be controlled, but long-term medication is required. Mainly because of the neural pathways, the brain inside the nerve pathway dopamine level disorder.

Parkinson's is a lack of dopamine in the body.

Most patients have tremor as the first symptom, which mostly begins in the distal upper limb on one side, appears or is obvious when at rest, lessens or stops when moving voluntarily, intensifies when nervous, and disappears after falling asleep. Resting tremor of the hand is worse when walking.

Parkinson's disease is a chronic progressive neurodegenerative disease that is common in middle-aged and elderly people. In the patient's brain, there is a lack of a chemical called dopamine, which is a neurotransmitter that acts like a special messenger in the brain that is responsible for transmitting commands from the nervous system to the muscles with moderate accuracy, directing the muscles to work. Without dopamine, nerve control commands cannot be conveyed correctly, and disobedient hands and feet will occur.

Parkinson's disease** is complex, and the factors that cause Parkinson's disease to be insidious may include:

1. Age: The onset of the patient's Otomo land part is between 50 and 60 years old, and with the increase of age, the function of nerve cells weakens, and the secretion of dopamine decreases, resulting in an increase in incidence;

2. Heredity: 5%-10% of patients have genetic cause schizin, and the probability of suffering from Parkinson's will also increase;

3. Environment: Causes include climate deterioration, haze weather, food pesticide residues, etc.;

4. Lifestyle: high pressure, fast pace, lack of sleep, nervousness, anxiety, etc.

The occurrence of Parkinson's disease is related to the degeneration and death of dopaminergic neurons in the substantia nigra, but what exactly causes these, the degenerative death of neurons, has not been clear, and may be related to a variety of factors, including genetic factors, environmental factors, nervous system aging and other basic **, genetic factors, it is currently believed that 10% of patients have a family history, and the vast majority of patients are sporadic, environmental factors in the environment and, Shishen, intensive reading, one, methyl, four, native, 123, hexa, tetrahydropyridine MP Industrial or agricultural toxins with a similar TP molecular structure, such as certain pesticides, herbicides, rotenone, etc., may be one of the most common causes of Parkinson's disease.

Genetic factors. It is thought that 10% of patients have a family history, and the vast majority of patients are sporadic.

Environmental factors:Industrial or agricultural toxins in the environment that are similar to the neurotropic 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) molecular structure, such as certain pesticides, herbicides, rotenone, etc., may be one of the most important causes of Parkinson's disease.

Aging of the nervous system.

Some data show that after the age of 30, with age, the substantia nigra dopaminergic neurons begin to show degeneration, but not all of them lead to Parkinson's, aging is the most important factor in the occurrence of Parkinson's disease.

Multi-factor interactions.

Genetic susceptibility increases the likelihood of developing the disease, except in a small number of people with familial Parkinson's disease, except for a small number of people with familial Parkinson's disease.

It is due to the combined effect of environmental factors, aging of the nervous system and other factors that will lead to the onset of the disease.

Parkinson's is an extrapyramidal disease and one of the common diseases of the elderly. In general, common clinical manifestations include resting tremor, bradykinesia, muscle rigidity, and decreased facial expression, such as blinking. There may also be constipation, sleep disturbances, autonomic dysfunction, cognitive impairment and other conditions.

What are the symptoms of early Parkinson's?

Most of the symptoms of early Parkinson's disease are slowness of movement, as well as resting tremor or stiffness of the hand. There are many causes of hand tremor in the elderly, most of which are caused by pyramidal system or extrapyramidal diseases, and the common cause of hand tremor is Parkinson's disease. In addition, the factors that cause hand tremor in the elderly include microcephaly, Wilson's disease, and common senile tremor.

Can Parkinson's syndrome be a**?

Parkinson's syndrome is not a chronic degenerative disease, and there is no complete way to do it in both Chinese medicine and Western medicine. However, symptoms can be improved with medications. Some of these patients can be treated with Western medicine surgery**.

Therefore, Parkinson's is mainly drug control and improvement of symptoms, delay the development, and patients with surgical indications and no contraindications to surgery can improve symptoms through surgery**.

How does TCM ** Parkinson's disease?

Parkinson's disease is mainly a deficiency syndrome, which is divided into hyperactivity of liver yang, qi stagnation and blood stasis, and liver and kidney insufficiency, which should be treated according to different clinical types of diseases. For example, hyperactivity of liver yang should be based on nourishing the liver and kidneys, flattening the liver and latent yang, and qi stagnation and blood stasis should be mainly based on soothing the liver and regulating qi, invigorating blood and removing blood stasis.

The cause of Parkinson's disease is not fully understood, and it is currently thought to be mainly related to genetic, environmental, neurological, and systemic aging, as well as a number of other factors.

1.Genetic factors. At present, some studies believe that the vast majority of Parkinson's patients are sporadic, and a small number of patients have a family history.

2.Environmental factors:Certain toxins in the environment, such as some herbicides, pesticides, etc., can cause Parkinson's disease.

3.Aging of the nervous system. The incidence and prevalence of Parkinson's cave examination increase with age. Aging is one of the important causes of Parkinson's disease.

4.Other factors such as solalan: Traumatic brain injury, smoking, and coffee drinking may also increase or decrease the risk of Parkinson's disease.

The causes of Parkinson's disease are not fully understood, but they are known to include genetic factors, environmental factors, and neurological aging.

Some Parkinson's patients have a certain hereditary gene, and epidemiological investigations of Parkinson's disease patients have found that Parkinson's disease has a certain familial cluster. However, about 10% of patients with Parkinson's disease have a family history, and the vast majority of cases are sporadic.

Environmental factors, such as a history of carbon monoxide poisoning, traumatic brain injury, and long-term exposure to heavy metals, are associated with a higher risk of developing Parkinson's disease than the general population. Certain pesticides, herbicides, rotenone, etc., may also be one of the most important causes of Parkinson's disease.

Since the incidence of Parkinson's disease gradually increases with age, it is inferred that dopaminergic neurons in the substantia nigra degenerate with age, leading to a decrease in dopaminergic neurons, which in turn leads to an increase in the incidence of Parkinson's disease as people age.

In addition to the above factors, immune or emotional factors may also trigger Parkinson's disease. In addition, Parkinson's disease is not necessarily caused by a single factor, but may be caused by a combination of factors.

There has been no clear conclusion on either Parkinson's disease or Parkinson's disease, and research in this area has never stopped. Regardless of the cause of Parkinson's disease, early diagnosis and active protection** are beneficial to improve the quality of life and prolong the life of patients.

The main pathological change of Parkinson's disease is the degeneration and death of dopamine (DA) neurons in the substantia nigra of the midbrain, resulting in a significant decrease in the content of DA in the striatum. The exact cause of this pathological change is still unclear, but genetic factors, environmental factors, aging, oxidative stress, etc. may all be involved in the degenerative death process of PD dopaminergic neurons.

Speaking of Parkinson's disease is now a very common disease for the elderly. What exactly causes the onset of the disease, first of all, the environmental rotten factor; Some scientists have found that some toxic substances will produce symptoms similar to Parkinson's if injected into the brains of monkeys, such as a substance called MPTP injected into the brains of monkeys. Later, scientists experimented with toxic substances on mice, and the rats were given toxic substances through experiments, and found that mice also exhibited Parkinson-like movements.

Later, after the autopsy of a patient with Parkinson's disease, some toxic substances were found in the brain, and the toxic substances were similar to those found in the farmer's grandson's medicine, that is, there were some pesticides called paraquat, and the farmer's herbicide was called paraquat, and if the medicine was given to mice, it would produce similar symptoms. Therefore, it is believed that environmental factors may play a role in Parkinson's; Another role is genetic factors; Genetic factors in Parkinson's disease are also related aspects in the pathogenesis, in 1996 the first Parkinson's disease gene was identified in Italy, so the cause of Parkinson's disease is not very clear now, mainly because it is thought that environmental factors and genetic factors work together as a result.

The formation of Parkinson's disease may be associated with a decrease in dopamine content.

Parkinson's is a neuropathic disorder caused by the lesion of dopaminergic nerve cells in the substantia nigra of the midbrain, resulting in a significant decrease in the amount of dopamine, thus hindering the brain's ability to command muscles.

Simply put, the decrease in dopamine leads to Parkinson's.

Dopaminergic neurovacancy cells are used to secrete dopamine.

The dopaminergic nerve cells in the brain of Parkinson's patients do not know what to dopamine and die, resulting in a significant decrease in dopamine levels.

Parkinson's disease, which is common in older people, is a chronic degenerative change that tends to present with resting tremors, slowed movements, and muscle rigidity. At present, Parkinson's disease is not completely clear, and it may be due to various reasons that cause a decrease in dopamine neurotransmitters in the substantia nigrastriata and thus cause corresponding extrapyramidal symptoms. Common risk factors are age, and Parkinson's disease is more common in patients over 50 years old, especially the older the patient, the higher the incidence of Parkinson's disease.

Some patients with early-onset Parkinson's disease have a positive family history and genetic abnormalities. In some cases, exposure to toxic substances, such as pesticides or herbicides, can also increase the risk of Parkinson's disease. In conclusion, the nature of Parkinson's disease is not fully understood.

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