What are the sterilization environment and use characteristics of ethylene oxide sterilizer?

Ethylene oxide sterilizer is a device that uses ethylene oxide gas as a sterilant. It can kill all kinds of microorganisms at room temperature, including spores, Mycobacterium tuberculosis, bacteria, viruses, fungi, etc.

Ethylene oxide sterilizers are mainly divided into 3 categories:

Large ethylene oxide sterilizer: generally used for the sterilization of a large number of processed items, the dosage is, at 55 60 for 6h.

Medium-sized ethylene oxide sterilizer: generally used for sterilization of disposable medical supplies. Pros:

The equipment is perfect, the degree of automation is high, and pure ethylene oxide or ethylene oxide and carbon dioxide mixed gas can be used. Generally, the sterilization conditions are: concentration 800 mg l 1000mg l, temperature 55 60, relative humidity 60% 80%, action time 6 h.

Vacuum is required to complete the sterilization, and the sterilized items are often sealed with plastic film that can pass through ethylene oxide.

Small Ethylene Oxide Sterilizers: Mostly used in the medical and health sector to process small quantities of medical devices and supplies, there are currently 100% pure ethylene oxide or ethylene oxide and carbon dioxide mixtures. It can be automatically vacuumed, automatically dosed, automatically adjusted temperature and relative humidity, and can automatically control the sterilization time.

Sterilization environment requirements:

The items to be sterilized must be thoroughly cleaned, not cleaned with normal saline, and there should be no water droplets on the sterilized items, so as not to cause ethylene oxide dilution and hydrolysis. Ethylene oxide can be used for the sterilization of almost all medical supplies, but it is not suitable for the sterilization of food, liquids, oils, talcum powder and animal feed. Paper, composite dialysis paper, cloth, non-woven fabrics, ventilated rigid containers, polyethylene and other packaging materials can be sterilized with ethylene oxide; Metal foils, polyvinyl chloride, cellophane, nylon, polyester, polyvinylidene chloride, and impermeable polypropylene cannot be sterilized with ethylene oxide.

Characteristics of use:1Within a certain range, the temperature increases and the concentration increases, which can shorten the sterilization time. When sterilizing with ethylene oxide, temperature, concentration and time parameters must be selected reasonably.

2.Control the relative humidity of the sterilization environment and the moisture content of the article: The moisture content of the bacteria itself and the moisture content of the sterilized article have a significant impact on the sterilization effect of ethylene oxide.

In general, a relative humidity of 60% to 80% is best. If the water content is too small, it will affect the penetration of ethylene oxide and the alkylation of ethylene oxide, and reduce its bactericidal ability; Too much water, ethylene oxide is diluted and hydrolyzed, which also affects the sterilization effect. In order to achieve the ideal humidity level, the first step is that the sterilized product must be pre-wetted first, and the sterilized product is generally required to be placed in the environmental condition of 50% relative humidity for at least 2 hours; The second step is to use a humidifier to ensure the ideal humidity level in the cabinet.

3.Pay attention to the effect of the external protective substance on the sterilization effect: the more organic matter contained on the surface of the bacterium, the more difficult it is to kill; Organics can not only affect the penetration of ethylene oxide, but also consume part of ethylene oxide.

Microorganisms in inorganic salts or organic crystals are difficult to kill with ethylene oxide. Therefore, before ethylene oxide sterilization, the organic and inorganic dirt on the article must be fully cleaned to ensure successful sterilization.

Generally speaking, the modern automatic ethylene oxide sterilizer must be able to provide quality control of the four basic parameters of seedling time, sterilization temperature, gas concentration and relative temperature in the cavity, so as to avoid the sterilization failure of Henan Sanqiang ethylene oxide and have a high safety guarantee. Generally, the sterilizer is exposed to ethylene oxide gas for a period of 1-8 hours (the mixed gas has a longer time to kill the seedlings). There are generally two sterilization temperatures:

The hot cycle is 49-60 and the cold cycle is. Gas concentrations can vary from 450-1200 mg L, and the relative humidity in the chamber ranges from 30% to 70%.

When purchasing an ethylene oxide sterilizer, it is necessary to fully understand how the ring stage ethane sterilizer controls these key parameters, and if the parameters do not meet the standard, whether the sterilizer has the function of terminating sterilization. Therefore, the ethylene oxide sterilizer must be designed with the following characteristics to ensure its safety:

Automatic closing of the door lock: After the ethylene oxide gas is released, the pot door must automatically close and cannot be opened. If you need to forcibly stop the cycle, you must wait for the ethylene oxide gas to be discharged before opening the pot.

The door is well sealed: it can ensure that ethylene oxide gas is not easy to leak out during positive pressure sterilization.

Groove gasket: It not only ensures that the door is not easy to be damaged when it is opened or closed, but also ensures that the seal is complete due to its special sealing performance.

Vacuum and pulse washing: After sterilization, vacuum and pulse washing should be effective in removing ethylene oxide residues.

Alarm: Once the machine fails, including ethylene oxide leakage, the machine can alarm loudly in time.

Automatic exhaust: In case of power failure and other failures, the ethylene oxide in the pot can be automatically discharged.

The sterilizer has the dual function of sterilization and ventilation: after the sterilization is completed, it directly enters the ventilation stage, and after the ventilation is completed, the items can be used directly after they are taken out.

Ethylene oxide sterilization is suitable for medical devices, such as pacemakers, dialyzers, suction devices, etc., and is also suitable for epidemic prevention materials, such as protective clothing, goggles, forehead thermometers, respiratory protectors, etc., in addition to sanitary products, such as sanitary napkins, diapers, napkins, wet wipes, etc. Readers who want to continue to understand what items ethylene oxide sterilization applies to can read on.

What are the advantages and disadvantages of ethylene oxide sterilization.

1. Ethylene oxide is considered to be a chemical sterilant with the best sterilization effect, which can kill all microorganisms, including bacterial spores.

2. Ethylene oxide sterilization track has strong penetration, and can be used for sterilization of various difficult to penetrate parts, such as some thinner and longer catheters are difficult to achieve the sterilization effect with other low-temperature sterilization methods, and can only use ethylene oxide or irradiation.

3. The disadvantages of ethylene oxide sterilization hail are that the whole sterilization cycle takes a long time, and the reason is that it needs to be ventilated for a long time to remove ethylene oxide residues.

4. The disadvantages of ethylene oxide sterilization are that ethylene oxide is flammable and explosive, and cannot be leaked during storage and sterilization. A safe sterilizer must be selected for safe handling and storage.

Ethylene oxide is a spectral sterilant that kills a variety of microorganisms, including spores, Mycobacterium tuberculosis, bacteria, viruses, fungi, etc., at room temperature. At present, ethylene oxide is widely used in medical devices for sterilization.

Ethylene oxide sterilization device is the key equipment of disposable sterile medical device manufacturers, and the installation operation and use management of the file and installation have their own special requirements, which is the focus of safety prevention and supervision. Ethylene oxide is a flammable and explosive toxic gas, with the molecular formula C2H4O, with an aromatic ether smell, at 4 °C, the relative density is, the boiling point is, and its density is, at room temperature, it is easy to volatilize into gas, and when the concentration is too high, it can cause **.

The four elements of ethylene oxide sterilization: temperature, humidity, concentration, and time;

The temperature is generally between 30 and 70 degrees, and the temperature is positively correlated with the sterilization effect, but it should not be too high, because the advantage of ethylene oxide sterilization is low-temperature sterilization;

The humidity is generally between 30 and 80rh, and after it is greater than 30rh, the increase of humidity will not significantly improve the sterilization effect.

The EO concentration is mostly 400 800mg L in actual operation, and the higher the concentration, the better the effect and the shorter the time;

Time is positively correlated with sterilization effect, but it is not linear, but a power-like relationship.

The specific selection needs to be determined by process confirmation.

Ethylene oxide is used in a wide range of applications for medical disinfection and industrial sterilization:

1. Medical devices: pacemakers, artificial hearts, dialyzers, suction devices, oxygenator replaceable elements, surgical automatic staplers, sutures, artificial esophagus, artificial bones, artificial blood vessels, etc.;

2. Epidemic prevention materials: masks, masks, protective clothing, goggles, forehead thermometers, respiratory protectors, etc.;

3. Civilian materials: express parcels, bed sheets and bedding, clothes, shoes and hats, carpets and blankets, towels and bath towels, plush toys, gauze bandages, cotton balls and cotton swabs, leather, fur products, furniture, etc.;

4. Kitchen utensils: cooking utensils, knives, dining utensils, etc.;

5. Cultural relics archives: banknotes, tickets, medical records, archives, letters, historical relics, silk satin products, animal and plant specimens, etc.;

6. Sanitary products: sanitary napkins, diapers, napkins, wet wipes, cotton pads, etc.;

7. Endoscope: laryngoscope, bronchoscope, esophageal fiberscope, mediastinoscope, cystoscope, urethroscope, thoracoscopy, etc.;

8. Rubber and plastic products: gloves, finger sleeves, syringes, injection needles, blood collection devices, infusion sets, urine collection bags, intra-organ hoses, nasal hoses, catheters, suction hoses, birth control equipment, etc.;

9. Textiles and biological products: cotton wool chemical fiber clothing, blankets, carpets, gauze bandages, cotton balls, cotton swabs, absorbent cotton, dressings, towels, leather withered and burned beard, fur products, etc.;

10. Medicine: some traditional Chinese medicine and Western medicine, some cosmetics, etc.;

11. Instrumentation: electronic instruments, optical instruments, first-class machines, etc.

The four elements of ethylene oxide sterilization: temperature, humidity, concentration and time;

The temperature is generally between 30 and 70 degrees, and the temperature is positively correlated with the sterilization effect, but it should not be too high, because the advantage of ethylene oxide sterilization is low-temperature sterilization;

The humidity is generally between 30 and 80rh, and after it is greater than 30rh, the increase of humidity will not significantly improve the sterilization effect.

The EO concentration is mostly 400 800mg L in actual operation, and the higher the concentration, the greater the sterilization effect before cherry blossoms, and the shorter the time;

Time is positively correlated with sterilization effect, but not linear, but power-like.

The specific selection needs to be determined by process confirmation.

The temperature is within 30 60 degrees, the humidity is 30 80%, and the pressure controllable range is generally -80 80kpa.

Ethylene oxide is a toxic gas, it is best to use negative pressure sterilization, the temperature of the sterilization chamber is between 30-70 degrees, the humidity is about 65%, the sterilization effect is the best, the sterilizer is best placed in Liang Sleepy an oak hunger room, and pay attention to the problem of disability, I hope to help you My Q137664532

The details are as follows.

1) Ethylene oxide is a gas sterilizer, which is suitable for the sterilization of various medical instruments (such as fiber gastroscopes, pacemakers, microscopes), valuables (such as clocks and watches, jewelry), leather products, chemical fiber fabrics, plastics, rubber and various documents that are resistant to heat and moisture.

2) Ethylene oxide has good diffusion and penetration ability, it can penetrate cellophane, yellow board paper (horse manure paper), PVC film, leather and thin layers of oil and water, so when sterilized, the article can be packaged without acceptance.

Effect. (3) Ethylene oxide gas is flammable and explosive, when the concentration in the air reaches more than 3%, there is a risk of burning in case of open flame and static electricity, and generally large doses must be packed in special pressure-resistant cylinders, and small packages of drugs below 50ml can be packed in thickened ordinary glass ampoules for later use.

4) Ethylene oxide has a certain toxicity to the human body, and excessive inhalation can cause dizziness, headache, nausea and vomiting, so the sterilizer should be closed without air leakage during operation, and an exhaust device should be installed in the disinfection room.

5) Ethylene oxide can be volatilized quickly at room temperature, and will not remain on the article, after sterilization, you can use a hair dryer to first pack the article with the package and blow it for 1 hour, and then disperse it for 24 to 48 hours before it can be used.

The safe operation of the ethylene oxide sterilizer is as follows:

1.It is used for the sterilization of items sensitive to heat and damp heat and all items that cannot be autoclaved.

2.Henan Sanqiang ethylene oxide sterilizer must meet the following conditions, such as water, electricity, steam (ethylene oxide gas, compressed air) before the sterilization process.

3.Ethylene oxide has good bactericidal power against various microorganisms, and its penetration is very strong, and it has little damage to articles.

4.Ethylene oxide, also known as "ethylene oxide", is a colorless and transparent liquid with an ether odor.

5.Gaseous ethylene oxide is flammable and explosive, and should be kept in a special ampoule or pressure-resistant metal canister.

6.Ethylene oxide sterilizers should be installed in a sterile environment, close to compressed air. An exhaust fan should be set up in this environment to remove the ethylene oxide gas diffused in the air in time.

7.Articles sterilized with ethylene oxide must be packaged in special standard paper-plastic packaging. Inside the bag is an instruction card. The sterilization date is generally 1-2 years.

8.For example, all kinds of items must be disinfected, especially all kinds of pipes must be guaranteed to be dry to prevent the sterilization effect from being achieved due to the presence of water.

9.It is strictly forbidden to sterilize oil products with ethylene oxide sterilizer. It fails to achieve the purpose of sterilization.

We must pay attention when using disinfection and sterilization equipment, especially in the process of use, a large amount of steam will be released, so as not to be scalded by hot gas, so we must be more careful in the process of use, and you can also wear anti-scald gloves, which will also avoid a lot of unnecessary trouble. Don't let the pressure temperature rise too fast, because in many cases due to the negligence of the operator, the temperature rises too quickly, which will have a great impact on the disinfection and sterilization equipment. Therefore, the operator must always pay attention to the temperature and pressure in the process of operation, and if the insulation and sterilization stage falls, the exhaust valve must be properly adjusted or the fire power must be increased.

The temperature should reach the specified value when keeping warm, some operators may be negligent, and the temperature will start to time before it arrives, which will lead to insufficient sterilization time and incomplete sterilization, so we must always pay attention to the temperature and pressure, and if it falls off in the insulation and sterilization stage, it is necessary to properly adjust the exhaust valve or increase the firepower. Don't let the pressure and temperature be too high, it may be many times, because the operator does not pay attention, the temperature and pressure rise too quickly, resulting in too high temperature, which is easy to hurt the equipment. Work while maintaining safety.

However, disinfection and sterilization equipment is a general term and not a separate equipment, and there are different requirements when it is used.