An article on professional medical language in medical testing and a Chinese translation are urgentl

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Mil-29 families (MiR-29A, B, and C) activate P53 against negative regulators, P85 and CDC42. This family has been extensively studied in chronic lymphocytic leukemia [123-125]. In lung tissue, miR-29s are considered an important factor for fibrotic marginal strips [126].

In lung cancer, the expression of miR-29s is negatively correlated with DNA methyltransferasesdnmt3a and dnmT3b [127], both of which are direct targets of miR-29S. Expression of miR-29s implemented in lung cancer cell lines inhibits tumorigenicity in vitroandin vivothrough demethylation and activates epigenetically TSGS silencing such as FHITAND WWOX [127]. Other important objective functions serve as mediators of Mir29 tumor suppression includettp [128] (regulation of cell polarity and metastasis) and BCL2 family recovery period1 [129].

Mir 1, Mir-133, and Mir-206 are three so-called "muscle-specific" microRNAs that are highly expressed in heart and smooth muscle tissue[130131]. They exhibit cancer-inhibiting activity in the lungs. downregulated Mir1 is found in primary cancer samples and cell lines [132].

Perform the expression Mir1 in A549 cells to inhibit cell growth and H1299, replication potential, motile migration, solitary survival, and tumorigenic mice [132]. The goal is to includemet to mediate these effects, PIM 1, HDAC4, andFoxP1. MIR-133-AIS indicates that energy is in reducing lung squamous cell carcinoma (SQCC) relative to normal tissue [133].

In addition, each mil can target several cancer pathways, although a key factor in the cancer network is usually mutated by regulatory requirements for heavy post-transcriptional levels of multiple miRNAs. The different functions of the athlete are based on the context of the cell (Fig. 1）。

A better approach to systematically identifying genes of interest targeting miRNA(s) or Mir regulators yields a more complete understanding of the key oncogenes of miRNAs in signal transduction. The involvement of miRNAs in cancer pathogenesis provides opportunities for novel cancer interventions. The use of miRNAs as biomarkers in lung cancer diagnosis, classification methods, diagnosis and evaluation of drug response is promising and needs to be further improved.

In larger populations, standardized business and analytical procedures with expression analysis have the potential to generate more reliable markers with enhanced sensitivity and specificity. Thira's pie based on the development of miRNA is still youngfield but thriving with the help of new delivery technologies like nanoparticles. Overall, we feel optimistic that Mil-based management of lung cancer will help tame in the future

In the English word formation of medical science and technology, the compound method, the conjugation method, the condensation method, the acronym method, etc., are commonly used, and these methods can be used as a reference in the translation of TCM terms.

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