Phagocytic cells Specific immunity, do phagocytic cells have specific recognition ability?

The function of phagocytes is to clean up their own aging and necrotic cells and bacteria that invade the body to engulf and dissolve them to destroy its pathogenic effect

In the immune response, the cells that can recognize antigens in a specific excitatory manner include B cells, T cells, memory cells, etc.

Phagocytes have the ability to recognize antigens but not specifically, and plasma cells (effector B cells) do not have the ability to recognize antigens.

Analysis of memory T cells, effector T cells, and memory B cells: memory cells (including memory T cells and memory B cells) specifically recognize antigens and then differentiate into effector cells, and effector T cells need to participate in cellular immunity, and their own contact with host cells will eventually lead to the lysis and death of host cells, which requires specific recognition in this process.

1.However, effector B cells (some of them are also called plasma cells) only destroy antigens by secreting antibodies, and they do not contact with antigens, so they do not have specific recognition ability, and it is antibodies that have specific recognition ability. 2.

Although phagocytic cells have the ability to recognize, they do not have the ability to specifically recognize files, and they only play the role of presenting antigens in the process of specific immunity, rather than recognition. The above two items should be paid more attention here.

No. Phagocytes have a recognition function, but not a specific recognition function. Cells in the body that have phagocytic function are collectively called phagocytes.

There are two types of phagocytic cells in humans: large and small. Small phagocytes are neutrophils in peripheral blood. Macrophagocytes are monocytes in the blood and macrophages in a variety of organs, tissues.

Phagocytic cells have the function of phagocytosis and digestion of senescent and dead cells and foreign bodies in the body, and are one of the important mechanisms of the body's natural defense. Phagocytosis of phagocytic cells is an important experiment in medical microbiology and immunology, which is mainly used to observe the ability of neutrophils and macrophages to engulf foreign microorganisms and other stupid particles, so as to reflect the body's natural immune defense function.

Recognition is the presence of a layer of glycoproteins (also known as glycocoats) on the surface of the cell membrane, which is closely related to the recognition of cells. The recognition of glycoproteins is like the words or languages used to communicate between cells, or between cells and other macromolecules. Cell recognition is a form of pattern recognition.

Question 1: Is immunity with phagocytes specific immunity? Not necessarily. It also has the effect of phagocytic cells in the prephase of cellular immunity.

Question 2: Are phagocytes specific or non-specific? Phagocytes can engulf pathogens in non-specific immunity.

The epitope of the antigen is processed in specific immunity (this treatment leaves the epitope inside the antigen exposed) and then the antigen is delivered to the T cells. In addition, after the antibody secreted by plasma cells (effector B cells) binds to the antigen, the Fc segment of the antibody can bind to the receptor on the surface of the phagocytic cell, thus engulfing and destroying the antigen!

Question 3: The following are not immune cells: ( ) a phagocytic cell b red blood cell c t cell d b fine human immune cells are: t lymphocytes, b lymphocytes, k cells, nk cells, dendritic cells, monocytes macrophages, granulocytes, mast cells, etc., red blood cells are a type of blood cells, but not immune cells Therefore, it is chosen:

b Question 4: The difference between immune cells and phagocytic cells Immune cells are mainly divided into specific immune cells and non-specific immune cells. Specific immune cells are mainly T lymphocytes and B lymphocytes, and phagocytic cells are non-specific immune cells.

There are two types of full-time phagocytic cells in the human body:

One is small phagocytic cells, mainly neutrophils, but also eosinophils; When the pathogen penetrates** or the mucosa reaches the tissues in the body, phagocytic cells first escape from the capillaries and aggregate to the site where the pathogen is located. In most cases, the pathogen is engulfed and killed.

The other type is macrophagocytic cells, that is, mononuclear phagocytic cell system, including monocytes and lymph nodes in peripheral blood, spleen, liver, lung, macrophages in the serous cavity, microglia in the nervous system, etc. If they are not killed, they travel through the lymphatic vessels to nearby lymph nodes, where they are further destroyed by phagocytic cells. This filtering effect of lymph nodes plays an important role in the body's immune defense, and generally only virulent and large numbers of pathogens may invade the bloodstream and other organs without being completely blocked.

However, phagocytic cells in the blood, liver, spleen, or bone marrow continue to engulf and kill pathogens.

Phagocytes can engulf pathogens in non-specific immunity. The epitope of the antigen is processed in specific immunity (this treatment leaves the epitope inside the antigen exposed) and then the antigen is delivered to the T cells. In addition, after the antibody secreted by plasma cells (effector B cells) binds to the antigen, the FC segment of the antibody can bind to the receptor on the surface of the phagocytic cell, thereby engulfing and destroying the antigen!

Our end of the world is indeed true.

A. Phagocytic cells participate in non-specific immunity (second line of defense), A is wrong;

b. Phagocytic cells participate in humoral immunity processes, B is wrong;

c. Phagocytic cells participate in the immune process of cellular transmission, c error;

d. Only plasma cells can synthesize antibodies, and phagocytic cells cannot synthesize and secrete antibodies