Genetic testing is too expensive, can I skip it if I have cancer?

If the patient's genetic test results show that the patient is used for targeted drugs**, then the role of targeted drugs** can play a role, which can kill the patient's liver cancer cells, and can prolong the patient's survival time and improve the patient's quality of life.

Cancer genetic testing is very necessary, due to the heterogeneity and particularity of tumors, the individual differences of each patient, the gene expression level is not the same, the gene expression is different, and the selection of targeted drugs depends on the results of genetic testing.

Genetic testing is generally required for cancer, because only genetic testing can guide the use of targeted drugs, and if the genetic test is positive, it is suitable for targeted drugs**.

Is it necessary to do genetic testing for lung cancer in Shanghai Zhongda Cancer Hospital-Huang Dize-Chief Physician-Department of Medical Oncology-Lung cancer?

Modern people attach great importance to health, especially in the case of high incidence of cancer, many people are worried that they will have cancer, or the potential risk of cancer, so they plan to do a genetic test first, through high-tech means to understand whether there is a disease in their body. But at present, there are many people who regret doing genetic testing, so what's going on? Let's take a look.

People regret doing genetic testing, because there are many risks in doing genetic testing to detoxify, and in the United States, it is strictly forbidden for any company to pass genetic testing ** cancer service, and there will be many unfavorable factors after genetic testing. In addition, for most people, genetic testing is not necessary, because its test results may not be of reference value, but people will feel nervous and anxious because of the test results.

In addition, people regret genetic testing, mainly because the testing company may take the tester's gene to do some illegal things, the gene is like a person's ID card, everyone's gene is different, when their genes fall into the hands of others, let others slaughter, the other party takes their genes to do some illegal and harmful things, and individuals cannot stop it.

Therefore, it is recommended that people do not go for genetic testing, and if they want to know whether they have cancer, they can go directly to the hospital for relevant examinations, and there is no need to spend money on genetic testing.

Real genetic testing costs thousands of dollars per site, and there are many types of cancer, and if you want to test them all, the cost is quite high. At present, some so-called genetic tests are not real genetic tests, but are through the detection of some physiological indicators, under the banner of genetic testing.

Correct selection of drugs to avoid drug abuse and adverse drug reactions Due to individual genetic differences, different people will react differently to foreign substances, so some patients may have drug allergies, redness, swelling and rash when using normal doses of drugs. According to the results of genetic testing, a specific program can be formulated to scientifically guide the use of drugs and avoid drug toxicity and side effects.

Clinical significance:1For the diagnosis of diseases such as the diagnosis of Mycobacterium tuberculosis infection, previously mainly relied on sputum, stool or blood culture, the whole test process needs to take more than two weeks, using the method of genetic diagnosis, not only the sensitivity is greatly improved, but also the results can be obtained in a short time.

2.Understand whether you have the pathogenic genes of familial diseases, ** The risk data confirm that 10% and 15% of cancers are related to genetics, and many diseases such as diabetes and cardiovascular and cerebrovascular diseases are related to genetic factors.

For example, people with cancer or polygenic genetic diseases (such as Alzheimer's disease, hypertension, diabetes, etc.) can find out the genetic genes that cause the disease, and then they can adjust their lifestyle in a targeted manner to prevent or delay the occurrence of diseases.

Reliable, not only for cancer, but also for cardiovascular diseases, genetic testing methods have great practicability and development prospects.

As an expert in the study of genes and hereditary diseases, Ma Duan first made it clear that not only cancer, but also cardiovascular diseases, genetic testing methods have great practicability and development prospects.

Its rapid development has brought new breakthroughs to the early warning, early diagnosis, drug efficacy and adverse reaction judgment, and prognosis evaluation of genetically related diseases, and has also accelerated the speed of disease search, pathogenesis research and new drug research and development. Therefore, there is no doubt that cancer genetic testing must be an important direction for human beings to prevent, defeat and even defeat cancer in the future.

It is indeed possible to do it for certain types of cancer. For example, breast cancer can detect high-risk groups. However, the usefulness of this test should not be overstated.

The reason for the national suspension is that there is no uniform standard, but the value of genetic testing cannot be denied because of this.

The mechanism of cancer is very complex, and the molecular mechanisms and histopathological pathways that lead to cancer are different for different cancers or even for patients with the same cancer - that is to say, there are many defects in genetic testing to prevent cancer, which is one of the reasons why the state "stopped".

Cancer is a very serious malignant tumor, and it is very necessary for patients with Xiaoliang in the Cancer Bureau to do genetic testing, because genetic testing is the basis for guiding and selecting the use of targeted drugs.

Patients with gene mutations will have obvious efficacy when using corresponding targeted drugs**, and patients without gene mutations are not suitable for targeted drugs**. The main methods of cancer are surgery, chemotherapy, radiotherapy, targeted drugs, etc., and targeted drugs are very effective methods.

At present, cancer genetic testing mainly targets some solid tumors, such as lung cancer, breast cancer, stomach cancer, esophageal cancer, colorectal cancer, liver cancer, bile duct gallbladder cancer, pancreatic cancer, gastrointestinal stromal tumor, head and neck cancer, cervical cancer, ovarian cancer, endometrial cancer, prostate cancer, bladder cancer, kidney cancer, melanoma, etc.

Molecular testing has revolutionized the cancer paradigm, and cancer has begun to enter a new world of personalization.

At present, in foreign countries, the US FDA (Food and Drug Administration) has mandated genetic testing such as EGFR and KRAS. Another authoritative organization, the NCCN (National Cancer Comprehensive Network**), has included genetic tests such as EGFR, KRAS, ERCC1, RRM1, and HER2 in the guidelines for cancer**. At present, the main technology of cancer gene detection is real-time fluorescence quantitative PCR (RT-PCR), which has the characteristics of high accuracy, strong specificity, high sensitivity, simple operation, wide application range and high throughput.

In China, with the strengthening of international academic exchanges and exchanges, more and more clinical experts have realized the significance and importance of such testing items.

1. People with a family history of cancer or polygenic genetic diseases are the most in need of genetic testing, through which they can know whether they carry genetic disease genes. People who are diagnosed with hereditary tumors can also get a more suitable plan by doing genetic testing. It is reported that the late Apple CEO Stephen Jobs spent $100,000 to sequence the tumor and his whole genome when he was suffering from cancer.

2. People with long-term diseases, such as 80% of liver cancer patients have a history of hepatitis B, and people with long-term stomach diseases belong to the high-risk group of gastric cancer.

3. People who have been exposed to highly polluted environments for a long time or have bad lifestyle habits can understand their propensity for different diseases through genetic testing.

In the past two years, China's genetic testing companies represented by BGI and Daan Gene have developed rapidly in China, and have reached the international leading level in some specific technologies.