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Anonymous users2024-02-06Kanamycin is an aminoglycoside antibiotic. It has good antibacterial effect on most Enterobacteriaceae bacteria such as Escherichia coli, Klebsiella, Enterobacteriaceae, Proteus, Shigella, Salmonella, Citrobacterium, Profedonia, Yersinia spp., etc.; Haemophilus influenzae, Brucella spp., Neisseria meningitidis, Neisseria gonorrhoeae, etc. are also mostly sensitive to this product. Kanamycin also has a role in staphylococci (methicillin-susceptible strains) and Mycobacterium tuberculosis, but is not effective against Pseudomonas aeruginosa.
Other gram-positive bacteria such as hemolytic streptococcus, pneumococcus, enterococci and anaerobic bacteria are mostly resistant to this product. In recent years, there has been a significant increase in drug-resistant strains, due to the production of aminoglycoside passivating enzymes by some bacteria, which makes them lose their antimicrobial activity. Kanamycin has complete cross-resistance with streptomycin and neomycin, and may have partial cross-resistance with other aminoglycosides.
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Anonymous users2024-02-05Bronchitis, penicillin and kanamycin are used together, and the effect is not ideal, I don't know what the doctor thinks.
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Anonymous users2024-02-04Name of the drug: kanamycin.
The English name is kanamycin
Description Kanamycin sulfate for injection: per bottle; 1g。
Injection (with kanamycin monosulfate): 500mg (2ml) per vial.
Ophthalmic solution: 8 ml (40 mg).
Compound kanamycin injection: each bottle contains kanamycin sulfate 360mg and trimethoprim 18mg (2ml).
Functions Some strains of Escherichia coli, Klebsiella, Enterobacteriaceae, Proteus, Mycobacterium tuberculosis and Staphylococcus aureus are sensitive to this product. Pyophyllum aeruginosa, gram-positive bacteria (except Staphylophylobacterium aureus), anaerobic bacteria, atypical mycobacteria, rickettsia, fungi, viruses, etc. are resistant to this product. Microorganisms have a certain degree of cross-resistance to this product and other aminoglycosides.
Intramuscular injection, 1 hour blood concentration peak, about 20 g ml, T1 2 about hours, plasma protein binding rate is very low, volume of distribution (VD) is, 90 percent of the drug is excreted in the urine in the original form within 24 hours after medication. This product is more likely to penetrate into pleural fluid and ascites. Effective concentrations cannot be achieved in cerebrospinal fluid.
It is used orally for intestinal infections caused by sensitive bacteria and as preparation for intestinal surgery, and has the effect of reducing the production of ammonia by intestinal bacteria, and has a certain preventive effect on hepatic coma in patients with gastrointestinal bleeding from liver cirrhosis.
Intramuscular injection is used for systemic infections caused by sensitive bacteria, such as pneumonia, sepsis, urinary tract infection, etc.
Dosage (1) Intramuscular injection or intravenous drip 1 time, 1 day 1; Children are given 15 25 mg kg per day in 2 divided doses. Intravenous infusion should be diluted with an infusion of about 100ml, the infusion time is 30 60 minutes, do not too fast.
2) Oral administration is used to prevent hepatic coma, 4g d, given in divided doses. Preoperative preparation: 1 g per hour, 4 times in a row (often combined with metronidazole).
Precautions (1) Patients with renal insufficiency should use with caution.
2) The toxicity of aminoglycosides is closely related to their blood concentrations. In order to prevent the sudden increase in blood concentration, this product can only be used for intramuscular injection and intravenous drip, which has the effect of inhibiting exhalation, and cannot be pushed intravenously to prevent accidents.
Biochemical description: An inhibitor of protein biosynthesis that binds to 30S ribosomes and causes misreading of the mRNA code. If a bacteria produces an enzyme that destroys kanamycin, it can become a resistant strain.
Kanamycin-resistant plasmids are often used as selection or marker genes in molecular cloning.
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Anonymous users2024-02-03a.Bacteriostatic agent for tuberculosis fungus.
b.Mycobacterium tuberculosis total fungicide, cTuberculosis is a semi-fungicide for the bacterium.
d.It has no effect on tuberculosis bacteria.
e.There is damage to peripheral nerves.
Correct Answer: a
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Anonymous users2024-02-02Kanamycin A, often referred to simply as kanamycin, is an antibiotic used for severe bacterial infections and tuberculosis.
Kanamycin A sulfate is the sulfate form of kanamycin A, the main component of kanamycin A, which is an aminoglycoside antibiotic isolated from Streptomyces kanamycin with antimicrobial activity.
kanamycin a, often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. it is not a first line treatment..kanamycin a sulfate is the sulfate salt form of kanamycin a, the major component of the kanamycin complex, an aminoglycoside antibiotic isolated from streptomyces kanamyceticus, with antibacterial activity.
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Anonymous users2024-02-01Banquet Answer]: b
Analysis: Streptomycin belongs to the aminoglycoside class of antibiotics, and its main adverse reactions are ototoxicity and nephrotoxicity. Kanamyces is a protein biosynthesis inhibitor, and its main adverse reaction is renal toxicity.
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