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Nowadays, there are more and more people suffering from thrombocytopenia, so many people are more concerned about the causes of platelets, here experts point out: infection can cause thrombocytopenia, the following is a specific introduction to the causes of thrombocytopenia caused by infection, I hope it can help patients. What causes thrombocytopenia due to infection?
Experts believe that the following reasons are the most important. (1) Immune mechanism: pathogens enter the human body, adsorb on the surface of platelets as antigens, and then bind to antibodies produced by the spleen, or the immune complex binds to platelets through platelet FC receptors, and is recognized and engulfed by macrophages in the human body, so that the destruction of platelets is more than that of normal people.
On the other hand, when the human body is infected by a virus, the number of FC or C3B receptors on macrophages increases, and the affinity increases, making platelets more easily destroyed. This is also one of the main causes of thrombocytopenia caused by infection. (2) Megakaryocyte violation:
Viruses and bacteria invade the bone marrow, and their continuous replication and toxins directly damage the proliferative and mature ability of megakaryocytes, causing their platelet-producing function to be impaired and platelet production to be reduced. (3) Causes of thrombocytopenia caused by infection: pathogens can activate platelets in the blood through the release of various toxins, aggregate and destroy, resulting in the reduction of circulating platelets.
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A cold is an acute upper respiratory tract infection that includes acute inflammation of the nose and throat. Most are caused by viral infections, and a few are caused by bacterial and other pathogens. Cold and fever can lead to different manifestations of the blood count, typically elevated or decreased neutrophils, elevated lymphocytes, elevated monocytes, and may also be seen with an elevated or decreased total number of white blood cells.
In general, it does not cause thrombocytopenia. Thrombocytopenic disorders occur only if the patient has comorbid hypocoagulation.
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The first symptoms of many diseases are cold symptoms. For example, leukemia. Many patients go to the doctor because of a cold, and they are found to have leukemia. Therefore, if a cold and fever cause low platelets, it is best to go to the hospital to check whether there is a problem with the hematopoietic system.
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Everyone knows that a cold can cause symptoms such as cough, fever, runny nose, dizziness, headache, mental exhaustion, and muscle aches. In addition to these common symptoms, colds can cause a number of other symptoms. Some colds, especially viruses, can cause blood problems, such as thrombocytopenia.
The thrombocytopenia caused by the cold will slowly return to normal after the cold has improved, and there is no need to correspond.
Most people will encounter cold or virus, headache, cough, fever or nasal congestion and other symptoms are caused by colds. Some people may notice thrombocytopenia after a cold. Can a cold cause thrombocytopenia?
This can be explained below.
1. Colds can cause thrombocytopenia.
After a cold, especially the virus** can cause symptoms of platelet reduction, so many people may have some symptoms such as bleeding gums or nosebleeds and eye congestion after a cold. In addition, if there are symptoms such as nosebleeds during a cold, it is not easy to stop bleeding, which is related to thrombocytopenia caused by colds. When thrombocytopenia occurs, the body's clotting mechanism is affected, so it is not easy to stop bleeding.
2. Causes of thrombocytopenia.
The reason why colds cause thrombocytopenia is that cold virus antigens will adsorb on the surface of platelets and combine with the corresponding antibodies to form immune complexes, which will destroy platelets and shorten the life of platelets. In addition, macrophages, neutrophils, etc., will be produced after a cold. These cells cause the pathogenic microorganism to react severely, and the inflammatory response is amplified, which causes platelets to be engulfed by phagocytic cells or platelets adhere to the endothelial cells of blood vessels, so thrombocytopenia symptoms occur.
Both of these causes lead to colds, and there is a possibility of thrombocytopenia.
Three**. Thrombocytopenia caused by colds is transient and is mainly caused by cold viruses and the inflammatory response caused by colds. For such thrombocytopenia, it is not necessary to take the corresponding **, but in this case, it is necessary to pay attention to actively deal with the cold, because only when the cold gets better and the cold virus disappears, the problem of thrombocytopenia will gradually recover.
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A cold is an upper respiratory tract infection caused by a virus, and the main symptoms are runny nose, nasal congestion, cough, etc., and thrombocytopenia can be manifested in severe cases.
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There is a problem with immunity, and it is necessary to strengthen the ** and food cooperation in terms of immunity.
**You haven't found it yet, now your disease must be changing, and when the disease stabilizes, and then find the disease, the person may be very dangerous, the doctor will next ask you to do spinal puncture, caudal vertebrae on the marrow extraction, check the hematopoietic function of the bone marrow.
If it becomes platelet purpura, it is troublesome.
Early detection**, followed by immediate symptomatization**, should be able to avoid platelet purpura.
You need to find an experienced and skilled doctor, and your test report, I don't think I have found the actual situation of the disease, platelet loss is just a superficial situation, there must be a reason for platelet lessness, but what is the reason? Hyperpyrexia? So why do you have a high fever?
I do not know. Thrombocytopenia caused by high fever is certainly not a direct factor. There must be a very important reason for this, let those good doctors continue to investigate.
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Most of your cases are thrombocytopenic purpura. However, it is necessary to go to the hospital for examination to rule out other diseases that cause low platelets, such as early aplastic aplasia, systemic lupus erythematosus, etc. **It should be a combination of traditional Chinese and Western medicine**, and simple Western medicine **easy**. Big.
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It is recommended that you go to the hospital for a check-up, and under normal circumstances, you will not have a regular low-grade fever. Frequent low-grade fever has a certain impact on physical health.
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Drugs that predispose to thrombocytopenia.
Benzene, xylene, etc. Alkylating agents: such as nitrogen mustard, cyclophosphamide, chlorambucil phenylpropionate, etc.
Antimetabolites: such as cytarabine, mercaptopurine, etc. Anticancer antibiotics:
Such as orthotetramycin, doxorubicin, etc. Others: such as organic arsenic, etc.
2.Drugs that can cause bone marrow aplasia or hypoplasia are: such as chloramphenicol, sulfonamides, penicillin, streptomycin, neo-blue I, trimethyldione, phenytoin, ethosuximide, antithyroid drugs (such as methimazole, propylthiouracil, hyperthyroidism), diabetes drugs (such as methylbutamide, chlorbutamide, chlorproproclamide, etc.), phenylbutazone, indomethacin, tranquilizers and sedatives (tranquil, chlorpromazine, chlorpromazine, etc.), gold preparations, hair dye liu, priminin, chlorpheniramine, acetazolamide, etc.
3 .Drugs that selectively inhibit the production of platelets by megakaryocytes: such as chlorothiazides, estrogen, ethanol, mesulfonbutamide, reisdemycin, etc.
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Hello:1Decreased platelet production:
1) Idiopathic thrombocytopenic purpura, chronic aplastic anemia (CAA) and myelodysplastic syndrome (MDS): some patients can first present with thrombocytopenia, and then other blood cells can be reduced, bone marrow smear and bone marrow biopsy have certain distinguishing significance.
2) Infection: Seen in children with acute idiopathic thrombocytopenic purpura.
3) Decreased platelet production after radiotherapy and chemotherapy.
2.Increased platelet destruction:
1) Caused by autoimmune diseases: such as systemic lupus erythematosus (SLE), rheumatoid arthritis, Evans syndrome, hyperthyroidism, chronic hepatitis, etc., which cause decreased platelet production. Therefore, screening tests such as antinuclear antibodies and anti-double-stranded DNA antibodies should be routinely performed in patients with suspected ITP, especially young women.
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There are many factors that lead to thrombocytopenia, but the onset is the result, he belongs to a human immune mechanism deficiency disease, once it is found that it must be taken, the patient's value is indeed very low at present, and the value needs to be hospitalized to stabilize the value, but it can only be a temporary alleviation of the condition, can not be fundamentally **, if you want to achieve a thorough ** from the root, you must combine the conditioning of Chinese herbal medicine, Dr. Niu.
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Theoretically, some antipyretics can kill some blood cells. But platelets only 11 is definitely not a factor of the drug, don't be suspicious of the hospital. It is likely that there are other diseases, so let's do further tests and don't delay the condition.
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Analysis: There are many causes of fever, such as bacterial infection, viral infection, cold, etc. Attention should be paid to the selection of drugs with small group code segments. In the case of not exceeding the above, it is mainly to drink more water.
Opinion modeling: If it is exceeded, it is necessary to actively use antipyretic drugs and actively carry out physical cooling. At the same time, drink plenty of fluids and actively take blood tests if necessary to confirm the condition. Yes, it can be good.
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