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Antibiotics were previously called antibiotics, which are derived from the metabolites of certain microorganisms. Generally, as long as a very low concentration is used, it can inhibit the growth or even kill many bacteria, molds, mycoplasma, ricklidia, etc.
There are many types of antibiotics, and there are no less than dozens of antibiotics used in medicine and veterinary medicine in China. Different antibiotics work differently on pathogens
1.Some antibiotics interfere with the synthesis of the cell wall of bacteria, so that the bacteria cannot resist the invasion of water due to the lack of a complete cell wall, and swell, rupture and die.
2.Some antibiotics damage the cell membranes of bacteria, and bacteria die due to the loss of internal substances.
3.Some antibiotics can hinder the protein synthesis of bacteria and stop the reproduction of bacteria.
4.Some antibiotics affect the synthesis of DNA by altering the metabolism inside the bacterium, so that the bacteria (and tumor cells) cannot re-replicate the new cellular material and die.
There are many types of antibiotics, which can be classified according to their chemical properties; It can also be classified according to the range of antimicrobials (antimicrobial spectrum); In addition, they can also be divided into bactericidal antibiotics in the reproductive period, bactericidal antibiotics in the quiescent period, fast-acting antibiotics and slow-acting bactericidal antibiotics.
In the current practice, antibiotics are usually classified according to the scope of antibacterial, that is, a wide variety of antibiotics are divided into anti-Gram-positive bacterial antibiotics, anti-Gram-negative bacterial antibiotics and broad-spectrum antibiotics, and broad-spectrum antibiotics have antibacterial effects on both Gram-positive and Gram-negative bacteria; In addition, certain antibiotics that are designed to inhibit or kill mold are classified as antifungal antibiotics.
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Antibiotics are developed by humans to killPathogensof medications. Antibiotics have the effect of inhibiting or killing pathogenic microorganisms, and also have anti-tumor,Antiviraland other functions.
Antibiotics can inhibit bacteriaCell wallof the synthesis. If the cell wall of the bacteria cannot be synthesized, this will lead to the rupture and death of the bacterial cells. Antibiotic drugs that have this function include penicillins and cephalosporins, among others.
One of the principles of antibiotics to kill bacteria is that antibiotics can affect bacteriaProteinsThis means that the cell is necessary for survivalEnzymesCannot be crafted. Antibiotics canSelectiveThe role of the protein synthesis system is part of the characteristic. Antibiotics that interfere with protein synthesis include:
Doxorubicin, tetracycline, chloramphenicol, and many more.
Some antibiotics can interact with cell membranes, which can affect cell membranesPermeability, which is fatal to the survival rate of bacteria. Antibiotics that act in this way have polysmectins and brevis bacilli.
Antibiotics are inAll over the worldThe principles behind these are popularized in the field of medicineCauses。Antibiotics are oneActive substance, which is different from other chemically functional fungicides. Different concentrations of antibiotics have different effective effects on different microorganisms.
The widespread use of antibiotics effectively inhibits common bacteria and objectively reduces competition in the microbial world to enhance the body's resistance.
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For antibiotics, it can be said that we are quite familiar with it, whether it is ourselves, or our families, friends and classmates, when we have a cold, we will more or less use antibiotics to resist germs, so that we can achieve the best effect. Let's take a look at why antibiotics can destroy bacteria. What is his principle, let's take a look at it together.
One. Interferes with the synthesis of the cell wall of bacteria
Bacteria also have a cell wall, and the growth and development of bacteria are inseparable from everything in the body. Therefore, there are some antibiotics that specifically deal with this, they specifically interfere with the synthesis of the bacterial cell wall, and the bacteria will also lack the cell wall, unable to resist the entry of water, and eventually swell, rupture and die.
Two. Alters the metabolism inside bacteria
Metabolism is very, very important for people, animals, and bacteria. Metabolism promotes reproduction and reproduction. Antibiotics inhibit the growth of bacteria by changing the metabolism inside bacteria, and eventually make the bacteria die and disappear.
Three. Destroy the part that produces protein
Protein is key for us, because we often hear people talk about protein supplementation and nutrition. So for bacteria too, protein is indispensable. Bacteria lack the part that can produce protein, so they cannot replenish their bodies with nutrients, and eventually stop reproducing due to lack of nutrients.
All in allAntibiotics still have certain benefits and effects on some colds, but antibiotics cannot be abused, because antibiotics can inhibit the antibodies produced by our body to a certain extent, so that people will be more likely to catch a cold.
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There are many kinds of antibiotics, and the principle of action of different antibiotics is also different, some antibiolactins act on the cell wall volume of bacteria, affecting its synthesis and playing a bactericidal role; Some antibiotics affect the synthesis of bacterial RNA or DNA, which plays a bacteriostatic role; Some antibiotics affect the synthesis of bacterial folic acid and play a bactericidal or antibacterial role, etc.!
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d It's so simple; Just go home and get married.
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dAntibiotics kill pathogenic bacteria at the same time, they will also kill other bacteria in the body, such as Escherichia coli and other beneficial bacteria, so antibiotics have ***.
Antibiotics are medicines, and if left for a long time, they will react with the air and deteriorate.
Antibiotics should be avoided as much as possible when they are sick, and the misuse of antibiotics has become a major problem in the medical community.
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a. Antibiotics are produced by Penicillium in fungi, which can be a variety of bacterial diseases, and bacteria cannot produce antibiotics, a error;
b. Antibiotics are special substances produced by Penicillium that can kill or inhibit certain germs, and can be used for a variety of diseases.
b. Antibiotics are special substances produced by Penicillium that can kill or inhibit certain germs, which can lead to a variety of diseases.
d. Antibiotics are special substances produced by Penicillium that can kill or inhibit certain germs, rather than being artificially synthesized through a pure chemical process in a pharmaceutical factory
Therefore, b
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There are many kinds of antibiotics, and their ways of killing bacteria are also different, take lactam antibiotics as an example, they bind to the penicillin-binding protein on the bacterial cell membrane and hinder the synthesis of cell wall mucopeptides, so that they cannot be cross-linked and cause cell wall defects, resulting in bacterial cell rupture and death. Aminoglycosides cause membrane damage and inhibit mRNA transcription and protein synthesis. Others, such as quinolones, macrolides, glycopeptides, etc., have different mechanisms of action.
There are many species that simply inhibit their synthesis rather than killing bacteria directly.
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There are many kinds of antibiotics, and the principle of action of different antibiotics is also different, some antibiotics act on the bacterial cell wall, affecting its synthesis and playing a bactericidal role; Some antibiotics affect the synthesis of bacterial RNA or DNA, which plays a bacteriostatic role; Some antibiotics affect the synthesis of bacterial folic acid and play a bactericidal or antibacterial role, etc.!
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Antibiotics generally inhibit the formation of bacterial cell walls that are affected by multiplication.
Upstairs: Don't let antibiotics be used indiscriminately not because they are toxic, but because they are afraid that bacteria will evolve resistant individuals to form superbugs, and no amount of antibiotics will be useless.
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Each antibiotic has a different antimicrobial spectrum that inhibits or kills different bacteria. Although the antibiotic spectrum of various antibiotics is different, basically almost all bacteria can find corresponding antibiotics to fight against them.
Amoxicillin is a penicillin antibiotic, which has good antibacterial activity against non-lactamase-producing strains of aerobic gram-negative bacteria such as Streptococcus pneumoniae and hemolytic streptococcus, aerobic gram-positive cocci such as non-penicillinase-producing staphylococcus and Enterococcus faecalis, Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae and other aerobic gram-negative bacteria and Helicobacter pylori. Amoxicillin exerts a bactericidal effect by inhibiting the synthesis of bacterial cell wall, which can quickly make bacteria become spheroids and dissolve and rupture.
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For example, streptococcus that causes tonsillitis, staphylococcus that causes pneumonia, and Mycobacterium tuberculosis that causes tuberculosis.
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In fact, there are three mechanisms, one is acting on the cell wall, penicillin, cephalosporins, carbapenems, vancomycins.
The second is to act on ribosomes, erythromycin, clindamycin and some newly developed antibiotics abroad.
The third is to act on DNA, quinolones.
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No. To date, there is growing evidence that antibiotic administration early in life may have harmful long-term effects. Some animal studies have shown that high doses of antibiotics can cause long-term effects on behavior and brain neurochemistry.
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The discovery of antibiotics began with penicillin.