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Spinocerebellar ataxia is the main type of inherited ataxia. Common features are middle-aged onset, autosomal dominant inheritance, and ataxia. In addition to cerebellar ataxia, clinical manifestations may be accompanied by ocular movement disorders, slow eye movements, optic nerve atrophy, retinitis pigmentosa, pyramidal tract signs, extrapyramidal signs, muscle atrophy, peripheral neuropathy and dementia.
**。Caused by abnormal amplification of CAG copy number in exons of genes to produce polyglutamine.
Clinical presentation. 1.Infancy.
Walking with unsteady gait and shaky limbs. Slowness of motor response and poor accuracy.
2.Medium term. Speech is slurred and the pitch cannot be controlled. If the eye movement is not smooth, the image is prone to "overlap". Muscle incoordination worsens, and it is impossible to write. Sometimes I feel that I have difficulty swallowing and I choke easily when eating.
3.Advanced. Speech is extremely unclear, and it is impossible to speak. Limb weakness, unable to stand, need to rely on a wheelchair to walk. The ability to comprehend gradually decreases, and finally loses consciousness and falls asleep.
Examine. 1.Clinical examination of the cranial nervous system.
2.Magnetic resonance imaging (MRI) test.
3.Genetic testing.
**。This disease is a degenerative disease, and there is currently no drug that can be used, and the focus is on rehabilitation, so that patients can maintain the highest level of self-care ability as much as possible. It can also be done through stem cells**.
After **, the patient can recover the ability to take care of himself, move, speak, and write. Levodopa relieves tonic and parkinsonian symptoms, chloraniline butyric acid reduces spasticity, and amantadine improves ataxia.
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Disease analysis: If it is cerebellar ataxia, the main way is to use anti-inflammatory and hormonal drugs actively according to the doctor's instructions. In the case of deep sensory impairment ataxia, vitamin B12 supplementation is required to help reduce symptoms.
At the same time, patients can actively carry out ** training to promote recovery.
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Ataxia is a type of motor coordination disorder that occurs when the excitation is normal, and the limbs are in a state of voluntary movement, amplitude and coordination.
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1. Posture control training.
2. For the patient's balance dysfunction, the corresponding balance ability training should be carried out.
3. Speech training.
4. Gait training.
5. Frencel training: This training is a technique that relearns the central nervous system through repeated training, and the effectiveness of this method has been proved in the literature such as "Research on Ataxia Training and Recovery Time", "Frencel Training Method Combined with 41 Cases of Ataxia Patients with Segmental Blockage".
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Ataxia is a more stubborn disease, if it is more troublesome, it is best to combine Chinese and Western medicine.
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It should be mainly carried out for the potential, and the current effective methods are mainly symptomatic and effective.
What are the specialties for ataxia**?
****。Ataxia has a variety of conditions that are usually directed at the underlying condition, such as:
Cerebellar infarction due to acute cerebrovascular disease requires antiplatelet resistance.
or anticoagulation, lipid regulation to stabilize plaque and improve circulation;
Cerebellar mass lesions require neurosurgical resection;
Cerebellar ataxia caused by infectious inflammation or autoimmune inflammation that requires anti-infection.
and immunomodulation, etc.**;
For sensory ataxia caused by certain metabolic factors such as vitamin B12 deficiency, B vitamin supplementation may improve symptoms;
Vestibular ataxia due to benign paroxysmal positional vertigo requires manual reduction**;
For neurodegenerative and hereditary disorders, such as multiple system atrophy.
or spinocerebellar ataxia, for which there is currently no effective method.
****。For patients with ataxia, nerves are also an important component, especially for cerebrovascular disease.
Patients play a vital role in promoting neurological recovery and reducing the risk of disability.
Patients with neurodegenerative diseases such as multiple system atrophy and spinocerebellar ataxia can also benefit from ****.
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1. Drug conditioning.
After the patient has symptoms of ataxia, he or she should go to the hospital for examination, and the relevant ** regimen should be determined based on the results of the examination. Since ataxia is a chronic disease and is complex in itself, it is important to follow the doctor's instructions when taking medication and not to use it without authorization to ensure the efficacy of the drug. Patients can be conditioned by traditional Chinese medicine, which is less important to the body and also helps the body to recover.
2. Acupuncture**.
Patients with ataxia can appropriately use acupuncture and moxibustion of traditional Chinese medicine**, through pulse cutting, tongue coating, etc., combined with the patient's medical history, living environment and other factors, to carry out TCM dialectic**, and then reasonably formulate an acupuncture plan to prescribe the right medicine to help the patient alleviate the condition.
3. Function**.
Patients with ataxia need to do moderate exercise to help**, especially for patients with balance dysfunction, they should do more balance training, in addition to strengthening joint movement and muscle strength training, etc. The best training of balance function can help patients gradually resume daily functional activities, and the principle of moderation should be adopted in the training process, to avoid overwork, and to develop a reasonable training plan according to the patient's physical condition.
The above are some ways to improve ataxia, and patients should make a reasonable plan under the guidance of a professional doctor. In addition, patients should also pay more attention to keeping warm, insist on training physical functions, and carry out them in a scientific and effective way. You can activate the muscle strength through massage and promote the recovery of body functions, as long as you adhere to the long-term care and return of Hu Li and **, I believe that the patient's condition will definitely improve.
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Ataxia is a degenerative disease, and there is currently no drug that can be used. The focus is on rehabilitation, so that patients can maintain the highest level of self-care ability as much as possible, and through stem cells, patients can recover their self-care ability, mobility ability, language ability, writing ability, etc. Levodopa relieves tonic and parkinsonian symptoms, chlorphenabutyric acid reduces spasticity, and adamantane atrimide improves ataxia.
In addition, although there is no drug to help this disease, if you can pay attention to the maintenance of the body, pay attention to diet, daily life, regular exercise, cooperate with the rehabilitation training required by cerebellar atrophy, and persistent practice, it will help delay the deterioration of the condition.
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Three steps of cerebellar atrophy.
The first step: to achieve blood replenishment through blood replenishment, qi replenishment, blood filling, blood stasis and regeneration, etc. As a result, qi and blood are abundant, muscles and veins are nourished, and weakness and atrophy are improved.
Step 2: Strengthen the spleen and benefit the stomach, for patients with spleen disorder and stomach weakness and qi reversal, they should be given methods such as attacking and replenishing deficiency, raising and reducing turbidity, etc., to eliminate symptoms such as dysphagia, choking on food, water and cough, and muscle weakness.
Step 3: Nourish yin and benefit the kidneys, fill in the essence and marrow, strengthen the muscles and bones, improve the blood supply to the brain or the department, enhance intelligence, and restore limb function.
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Ataxia includes ** and ** for **, acute ataxia has some common diseases that can be targeted **, chronic dysfunction is most common in hereditary degenerative diseases, there is generally no specific ** method, and the diseases that cause acute ataxia include the following categories:
1. Cerebrovascular disease, including cerebral infarction and cerebral hemorrhage, needs to be given corresponding **.
2. Tumor, primary or metastatic tumor, paraneoplastic syndrome, need to be targeted for tumor**.
3. Metabolic diseases, including hypoglycemia, hyponatremia, hyperammonemia, Wernicke's encephalopathy, vitamin deficiency, and malnutrition.
4. Adverse reactions or toxicity of drugs, such as acute drunkenness and carbamazepine, cause acute ataxia, and it is necessary to stop the drug or reduce the dose of the drug.
5. Brain injury, trauma to the posterior fossa or edema of the brain can cause acute ataxia, and dehydration and intracranial pressure reduction need to be given**.
6. Immune-mediated diseases, such as multiple sclerosis and acute disseminated encephalomyelitis, need to be given filial piety hormones, gamma globulin, immunosuppressive excavators, etc.
7. Infection, various AIDS-related infections or other viral infections, such as Epstein-Barr virus infection, can cause acute ataxia and require antiretroviral **.
8. Polyradiculoneuropathy, such as the common Miller Fisher syndrome, requires gamma globulin shock**.
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The focus of ataxia is to target the lesion and improve the patient's living state.
1. Improve the posture basis of the patient's movement, enhance the proximal stability, improve the balance adjustment, and enable the patient to learn to move in a small range;
2. Improve the coordination of agon, synergistic and antagonist muscles, and make the patient's movement stable and smooth;
3. In the position of anti-gravity, let patients experience purposeful anti-gravity exercise;
4. Improve the coordination of the hand and the eye carefully, so that the patient can use vision to help stability;
5. Introduce the element of rotation into the patient's movement, so as to reduce the patient's restriction of voluntary or voluntary movement due to fear of disorder;
6. Train the patient to restore the normal sense of midline and verticality, so that there is a reference point to return to the midline during exercise.
Various pathologies have the potential to contribute to the occurrence of ataxia:
1: Peripheral neuropathy, peripheral neuritis caused by various **;
2: Spinal posterior medullary lesions, degenerated by posterior subacute combined spinal cord;
3: vestibular labyrinth lesions, such as vestibular labyrinth inflammation;
4: Cerebellar lesions, such as cerebellar hemorrhage, cerebellar infarction, cerebellar tumor, cerebellar inflammation, etc.
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Ataxia is mostly a hereditary disease, which is mainly manifested as unsteady walking and shaky limbs in the early stage, and slurred pronunciation, abnormal eye movement, and muscle incoordination may occur in the middle stage; In the late stage, he was extremely inarticulate and could not stand. This disease is a degenerative disease, and there is currently no drug that can be used, but the focus is on rehabilitation, so that patients can maintain the highest level of self-care ability as much as possible. It can also be done through stem cells**.
In addition, certain medications can relieve symptoms to some extent, such as levodopa to relieve tonic and parkinsonian symptoms, chloraniline butyric acid to reduce spasticity, and amantadine to improve ataxia.
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Ataxia is the most important positive primary disease, if it is caused by cerebrovascular lesions, it is necessary to pay attention to **cerebrovascular disease; In the case of cerebral infarction, anticoagulation, antiplatelet, or thrombolysis or endovascular intervention during the hyperacute period**; If intracerebral hemorrhage is present, surgery or medical care can be used**. In the early days, combined with acupuncture, training, and special means, such as transcranial magnetism, and degenerative cerebellar ataxia, among them, the recent stem cell transplantation technology also has a certain effect on spinocerebellar ataxia, but the technology is not very mature at present, and needs to be further studied and explored.
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Reduction of symptoms and signs of ataxia requires a comprehensive **. Ataxia According to ****, cerebellar ataxia such as ataxia caused by spinocerebellar degeneration, ** methods are relatively rare, because it is a disease caused by heredity; For example, ataxia caused by cerebellar inflammation requires anti-inflammatory, hormonal**, which can alleviate symptoms; Deep sensory impairment ataxia involves vitamin B12 supplementation to reduce the degree of ataxia. **Training can also reduce the degree of ataxia and enable patients to return to society and family as soon as possible.
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If it is a primary injury to the cerebellum, the doctor ** it has no special method, if the cerebellar mass causes ataxia, the neurosurgeon may also remove the tumor through surgery to relieve the symptoms. At present, there is no special way to completely treat ataxia, at present, there is only **exercise, slowly adapt, or there are peripheral nerves to compensate, usually strengthen functional exercises, and avoid falls.
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You should go to a regular hospital to see, find a specialist, they will help you, usually pay attention to rest, combine work and rest, nutrition, stay up late, and maintain a good mood, so that the disease can stay away from you.
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Depending on the cause, the type of ataxia or coping is different. The general principle is: primary disease, alleviate the symptoms of ataxia. Your doctor may do the following:
Diseases that cause ataxia: For some diseases that cause this symptom but can be asymptomatic, such as autoimmune diseases, head trauma, brain or cerebellar diseases, drugs, etc., ataxia can be alleviated by these diseases. The goal is to remove the ** that causes ataxia.
For example, ataxia caused by autoimmune diseases can be caused by taking drugs such as glucocorticoids and methotrexate.
If it is ataxia caused by head trauma, brain tumors, cerebellar tumors, etc., it can be controlled by surgical debridement and tumor resection.
If ataxia is caused by drugs***, the ataxia can be controlled by stopping or reducing the dose of the relevant drugs.
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