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Vitamin K is an important vitamin that promotes normal blood clotting and bone growth. Vitamin K in food is mildly damaged during cooking and is a nutrient that is readily available from food.
Dark green vegetables and yogurt are easily available vitamin K supplements in the daily diet. The human body's vitamin K requirement is very small, but it is to maintain the normal coagulation of blood function, reduce heavy bleeding during menstruation, and prevent internal bleeding and hemorrhoids.
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1. Blood clotting. The synthesis of some enzymes in the process of blood clotting is related to vitamin K, and vitamin K deficiency leads to coagulation dysfunction.
2. Vitamin K promotes bone reconstruction and calcium mobilization.
Above, ** in the "Nutrition and Health" book series.
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Vitamin K deficiency hemorrhagic disorder promotes the formation of prothrombin, accelerates blood clotting, and maintains normal blood clotting time.
Vitamin K2 is biologically active in animals, and both vitamin K1 and vitamin K3 are converted to vitamin K2 in order to work. All three forms of vitamin K are converted into vitamin K2 in the liver and absorbed together with vitamin K2 synthesized by gastrointestinal microorganisms.
In the past 40 years, especially in the past 20 years, due to the breakthrough in serum vitamin K and vitamin K deficiency-induced protein detection technology, many articles about infant bleeding caused by vitamin K deficiency have been reported around the world, and vitamin K deficiency is considered to be an important cause of infant bleeding disease and death worldwide. According to the 1995 National Child Mortality Surveillance Data, intracranial hemorrhage is the seventh leading cause of infant mortality in China, with a mortality rate of 100,000. Vitamin K2 preparations are effective in restoring prothrombin to normal levels and controlling bleeding.
Some elderly people also have vitamin K2 deficiency and prolonged prothrombin time; Prothrombin is also reduced when excessive use of dicarboxycoumarin for thrombosis prevention; In intravenous nutrition, antibiotics are added to the infusion solution to block the synthesis of vitamin K2 in the intestine; However, the conversion of water-soluble vitamin K3 derivatives into activated vitamin K is too slow and ineffective. Vitamin K2 deficiency can also occur when the biliary tract is obstructed, and must be given at the same time as bile salts when given orally or through the digestive tract.
In some liver diseases, vitamin K supplementation is ineffective to coagulation due to insufficiency and decreased coagulation factor synthesis, and vitamin K2 supplementation is required.
2. Vitamin KZ can prevent liver cirrhosis from progressing to liver cancer.
Japanese researchers reported in the July 21 issue of the Journal of the American Medical Association that daily vitamin K2 supplementation in women with viral cirrhosis may help prevent the development of hepatocellular carcinoma. This preliminary conclusion needs to be confirmed by large-scale clinical studies, and further research is needed on whether vitamin K2 has the same effect in male patients.
3. To prevent osteoporosis, vitamin K2 can promote the production of bone protein, and then form bone together with calcium, increase bone density and prevent fractures.
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Vitamin K is a fat-soluble vitamin, which is found in alfalfa, spinach, tomatoes and surimi, and is named K1 and K2 respectively. K3 (sodium bisulfite, menaquinone) and K4 (menaquinone) are both synthetics. Vitamin K is mainly involved in the coagulation process, it is an essential substance for the liver to synthesize prothrombin (factor), and also participates in the synthesis of coagulation factors, lack of vitamin K can cause internal bleeding or traumatic coagulation prolongation.
This drug is mainly used for bleeding disorders caused by vitamin K deficiency and vitamin K deficiency caused by various reasons.
Dosage Vitamin K1 injection, intramuscular or intravenous injection once, mg per kilogram of body weight for livestock, mg for dogs and cats.
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When it comes to vitamins, many people are aware of the benefits and functions of vitamin C, but in fact, vitamin K deficiency can also affect Hongtan's human health. So, what does vitamin K do? What are the consequences of vitamin K deficiency? How to supplement vitamin K scientifically?
Shao Qiang, a pediatric neurosurgeon at Wuhan Yangtze River Shipping General Hospital, said in an interview with the Hubei Channel of People's Daily Online that vitamin K is an essential substance for the synthesis of prothrombin.
Under normal circumstances, the body's vitamin K intake is not insufficient. However, the "Beijing Evening News" mentioned that with the increase of age, the change of dietary structure, the reduction of fat absorption rate, vitamin K is a typical fat-soluble vitamin, the reduction of fat absorption rate may lead to insufficient vitamin K intake, people who eat too little and take antibiotics are also prone to vitamin K deficiency, high dose intake of vitamin E may also interfere with survival, and the metabolism of vitamin K leads to vitamin K deficiency.
Shao Qiang said that once vitamin K is deficient, it can cause coagulation dysfunction, manifested as hemorrhage, such as cyanosis, ecchymosis, and in severe cases, it can lead to intracranial hemorrhage.
In addition, vitamin K1 deficiency and hypoxic-ischemic dermal encephalopathy can easily cause intracerebral hemorrhage in infants, especially preterm infants. Once bleeding, it is particularly easy to cause the "water circulation" in the brain to be disordered, forming hydrocephalus, which is life-threatening. Shao Qiang pointed out that children with hydrocephalus are prone to blockage of drainage tubes due to blood clots in the brain, and often cannot be carried out in time** and delay the disease.
As for vitamin K intake, according to the Beijing Evening News, it is 120 micrograms a day for adult men and 90 micrograms a day for women in the United States. The Chinese recommendation is similar, about 20 grams of spinach or 100 grams of broccoli.
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1. Promote blood coagulation, for women, vitamin K can reduce heavy bleeding during menstruation, and can also prevent internal bleeding and hemorrhoids.
2. Participate in bone metabolism, in addition to assisting in the synthesis of coagulation proteins, vitamin K also helps bone metabolism. The reason is that vitamin K is involved in the synthesis of BGP (vitamin K-dependent protein), which regulates the synthesis of calcium phosphate in bones.
Especially in older people, there is a positive correlation between their bone mineral density and vitamin K. Regular intake of green vegetables containing vitamin K can effectively reduce the risk of fractures.
3. It has an auxiliary effect on the synthesis of -carboxyglutamic acid. If vitamin K is deficient, the liver synthesizes the above four coagulation factors as abnormal protein molecules, and its ability to catalyze coagulation will be greatly reduced.
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Vitamin K is a kind of vitamin, yellow crystal, melting point 52-54, insoluble in water, soluble in ether and other organic solvents.
It has the effect of preventing bleeding diseases in newborn babies, preventing internal bleeding and hemorrhoids, reducing heavy bleeding during menstruation, and promoting normal blood clotting. There is more green vegetables.
Vitamin K controls blood clotting. Vitamin K is essential for the synthesis of four coagulation proteins (prothrombin, acceleration factor, antihemophilia**, and szeto factor) in the liver. Vitamin K deficiency can delay blood clotting; Causes neonatal hemorrhage, even if large amounts of vitamin K1 and the natural form of vitamin K2 are not poisonous.
If you are deficient in vitamins, it will be serious.
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