Can diabetic nephropathy be cured in the early stages? What kind of drugs are more effective?

This kind of disease can not be completely treated with the current medical conditions, our goal in the early stage of diabetic nephropathy is to control proteinuria, delay or minimize the occurrence of kidney failure, we need to control blood sugar, if the patient has hypertension we also need to use antihypertensive drugs, early patients can give priority to angiotensin receptor antagonists, or angiotensin-converting enzyme inhibitors, such antihypertensive drugs can control blood pressure and reduce urine protein to protect the kidneys.

In terms of the progression of the disease, the patient's condition will improve if the patient is active in the early stage of diabetic nephropathy. 1 in 3 patients with diabetic nephropathy can recover kidney function and proteinuria will disappear after **. In terms of medication, it is recommended that patients use new hypoglycemic drugs such as SGLT-2 inhibitors, such as canagliflozin, etc., and at present, SGLT-2 inhibitors are used as first-line drugs for diabetic nephropathy in the United States and China.

Moreover, the SGLT2 inhibitor canagliflozin has been confirmed in clinical studies to reduce the risk of renal function deterioration, renal dialysis transplantation and renal or cardiovascular death by at least 30% for patients with diabetic nephropathy, and at the same time allow patients to have multiple benefits in weight loss, glucose control, blood pressure reduction, and heart protection. Nowadays, SGLT2 inhibitor drugs have entered the medical insurance, and they can be dispensed in most parts of the country, and the ** has dropped significantly; Sugar friends are easier to obtain, and the burden has become smaller.

Some people seem to have kidney function recovery after **, **I have heard that SGLT2 inhibitors are quite effective.

Can you treat the state of the disease, at present, SGLT2 inhibitors are the first choice in the use of drugs.

Diabetic patients develop kidney disease, and generally about half of patients with diabetes develop renal insufficiency after 10 to 20 years. This is due to the fact that diabetic patients are a systemic capillary lesion, mainly due to the thickening of the capillary basal membrane, resulting in abnormal microcirculation, which causes abnormalities in many organs and organs, and the thickening of the glomerular capillary basement membrane can occur in the kidneys, resulting in glomerulosclerosis. Glomerular sclerosis affects the glomerular filtration function, causing a series of changes.

Diabetic nephropathy has become one of the important factors affecting the prognosis of diabetes.

Mild asymptomatic proteinuria usually occurs after about 5 to 10 years of diabetes, and the appearance of this phenomenon indicates that clinical diabetic nephropathy has begun. Proteinuria may be intermittent at first and become persistent later. Diabetic patients with obvious proteinuria have a worse prognosis than those without proteinuria, but there are great individual differences, and some patients can survive for more than 20 years, generally at least more than 10 years.

It takes several years for proteinuria to develop symptoms of kidney disease, such as edema and high blood pressure. In general, the longer the history of diabetes, the more severe glomerulosclerosis and proteinuria become. Once severe proteinuria develops, kidney disease can worsen more rapidly.

Nephrotic syndrome may occur if proteinuria progresses more severely and the proteinuria is greater than one gram per day. Diabetic nephropathy occurs in less than 10% of patients with nephrotic syndrome, and if it manifests as nephrotic syndrome, the prognosis is poor, and patients often die of renal failure and cardiovascular disease within 5 years. Other manifestations of diabetic nephrotic syndrome are the same as those of general nephrotic syndrome.

Diabetic glomerulosclerosis can also lead to gradual kidney failure after long-term moderate proteinuria. The speed of progression to kidney failure is quite inconsistent, and it usually takes many years for kidney failure to develop slowly. Once kidney failure occurs, the prognosis is very poor.

In renal failure, there is no significant reduction in kidney shrinkage and proteinuria. Without dialysis, the patient will die of uremia.

For patients with diabetes, the occurrence of diabetic nephropathy can be prevented, delayed or reduced as long as the diabetes is well controlled. Appropriate use of hypoglycemic drugs on the basis of dietary control can prevent secondary renal damage. Corticosteroids should not be used for diabetic nephropathy because they are not effective for proteinuria and nephrotic syndrome, but can also cause infections and make diabetes more difficult to control.

For more severe edema of nephrotic syndrome, diuretics can be used. If you have high blood pressure, you should use antihypertensive **, and vascular converting enzyme inhibitors are not only good for high blood pressure, but also for proteinuria and delay the occurrence of renal failure, and can be used routinely. Kidney failure is the same as kidney failure in general.

However, it should be noted that diabetes mellitus is sometimes accompanied by primary nephrotic syndrome, in which case corticosteroids** should be used, otherwise, it will accelerate the damage to the kidneys.

In the early stages of diabetic nephropathy, or in the second or third stages of diabetes, if the patient has only a small amount of proteinuria, the kidney lesions may be reversed if the blood sugar and blood pressure are well controlled. Diabetic nephropathy patients generally have a large amount of protein in their urine, and diabetic nephropathy can no longer be **, but it is also needed**, because a large amount of proteinuria will aggravate the progression of kidney disease.

Diabetic nephropathy is one of the microvascular complications of diabetes, with the continuous improvement of diabetes, the number of deaths from acute complications of diabetes has been greatly reduced, and the life of patients has been significantly extended, but the incidence of various chronic complications of diabetes, including diabetic nephropathy, has increased significantly.

Diabetic nephropathy cannot be treated from a pathological point of view, and from a clinical point of view, stage 1-3 (before the microalbuminuria period) can control blood glucose, blood lipids, and blood pressure stably, and stage 4-5 (after the urine protein is positive) cannot**.

According to your description, if there is diabetes complicated by kidney disease, it is best to be hospitalized**, mainly to control blood sugar, check kidney function, and then combine it with some drugs**. Usually you must drink more water, eat more vegetables, eat less raw and cold spicy food, do not eat high-fat food, relax your mind, go to the hospital in time to deal with the situation, and do not blindly use some drugs.

Diabetic nephropathy is a dangerous complication, and many believe that there is no cure. But I think it can be really hard in Western medicine. However, if Chinese medicine is used correctly and the syndrome differentiation is correct, it is also possible.

It's no problem for ten or twenty years, you can eat and do it. The congenital and acquired types are the same.

Generally, two to three days of Chinese medicine, if you feel a lot more comfortable, you can see hope. What a tirade is a bunch of nonsense!

Diabetic nephropathy is a disease caused by primary diabetes mellitus with benign arteriolar nephrosclerosis and malignant zhidao arteriolar nephrosclerosis, accompanied by corresponding clinical manifestations. The age of onset of diabetic nephropathy is more than 40 to 50 years old, and the history of diabetes is more than 5 to 10 years. In the early stages, only nocturia is increased, followed by proteinuria, and in some cases, transient gross hematuria may occur due to capillary rupture, but not with significant low back pain.

Diabetic nephropathy is often associated with arteriosclerotic retinopathy. The course of the disease progresses slowly, and a small number of people gradually develop renal failure, and most of them have impaired kidney function at a young age and abnormal urinalysis.

In fact, how to say that there is no disease that cannot be cured, only irresponsible doctors Have you ever been to Beijing** There are many authoritative nephrology hospitals in Beijing You can get ** here.

If the creatinine is lower than 200, it can be returned to normal, and it can be administered rectally with miniaturized Chinese medicine, if the creatinine is higher than this value, there are not so many healthy nephrons No matter what medicine or method is used, it can not return to normal, but the creatinine can be controlled not to grow or drop a lot to a certain extent, which is the best result.

Whether diabetic nephropathy can be cured is a matter of great concern to every patient. Numerous clinical and laboratory studies have demonstrated that early changes in diabetic nephropathy are reversible. Generally speaking, the glomerular lesions in the early stage of diabetic nephropathy are mild, and there is no substantial Sun Xiang shouting, after strict control of the normal range of blood sugar and urine glucose, it can improve the filtration environment of the glomerular basement membrane and reduce the ultrafiltration pressure of the glomeruli, so that the discharge of microproteinuria can be reduced, and even the condition can be restored to normal.

If diabetic nephropathy enters the middle and advanced stages, the glomeruli of the patient is seriously damaged, and the renal tubules are involved, macromolecular protein leakage, and the vast majority of patients are accompanied by hypertension, even if the blood sugar, urine glucose and blood pressure are satisfactorily controlled, and supplemented by other aspects, the urine protein discharge of patients with diabetic nephropathy can be improved to varying degrees, delaying the development of the disease, but it is difficult to recover kidney disease and reverse kidney function, which is very difficult at this time.

The above is mainly for diabetic nephropathy can be cured made a brief introduction, I believe you also understand after reading it, then I also hope that there is a timely acceptance of this disease, so as not to delay the best period of the disease, if you don't understand, you can ask me again.

If early diabetic nephropathy can be reversed, it is recommended that you should stick to it**, so that it will help you with your condition.

Diabetic nephropathy is one of the complications of diabetes, and its harm is very great. How to effectively prevent the further deterioration of diabetic nephropathy is the focus of many patients, and the following are several effective methods to control diabetic nephropathy.

Control high blood sugar

Patients should actively control hyperglycemia from the onset of diabetes and must ensure that blood glucose is strictly met. Because the better the blood sugar control, the lower the risk of diabetic nephropathy. The blood glucose target value is:

Fasting blood glucose "millimol liters", postprandial blood glucose "millimol liters, glycosylated hemoglobin <.

The criteria for special groups of older people can be appropriately relaxed.

Control high blood pressure

Actively control high blood pressure so that it is strictly up to standard. Therefore, patients should eat a low-salt diet, exercise appropriately, and actively supplement calcium. People with high blood pressure should continue to take antihypertensive drugs under the guidance of a doctor. The standard blood pressure is as follows:

Without renal damage and proteinuria, blood pressure should be controlled at <130 80 Hg; Urine protein" gram days, blood pressure should be controlled at <125-75 mm Hg.

Control of hyperlipidemia

Low-density lipoprotein (LDL) and high cholesterol are also risk factors for kidney disease. Therefore, patients with dyslipidemia should also be adjusted**. The standard value of blood lipids is:

Total cholesterol "millimolar liters", low-density lipoprotein "millimolar liters", high-density lipoprotein millimolar liters, triglycerides "millimolar liters".

Regular medical check-ups

When type 2 diabetes is confirmed, urine microalbumin screening should be done;

People with type 1 diabetes can be screened 5 years after the onset of the disease.

Patients who do not find microalbuminuria on initial screening should be tested annually thereafter.

Medications**

Once microalbuminuria occurs, regardless of whether there is no hypertension, ACE inhibitors or angiotensin receptor blockers should be taken under the guidance of a doctor. These drugs not only lower blood pressure, but also reduce albumin in the urine and slow the progression of kidney damage. Ginseng Qi hypoglycemic granules can be used in combination with other hypoglycemic drugs to maintain and control blood sugar.

At present, the most commonly used oral hypoglycemic drugs for diabetic patients include sulfonylureas, biguanides and -glucosidase inhibitors. The drug for the prevention and treatment of complications in diabetic patients is generally ginseng qi hypoglycemic granules.

It can be used in combination with Chinese and Western medicine to prevent and treat complications comprehensively. The traditional Chinese medicine ginseng qi hypoglycemic granules for the prevention and treatment of complications is better, its effect is stable, generally does not lead to hypoglycemia, is suitable for long-term use by diabetic patients, and has a certain protective effect on heart, liver and kidney function. It can be used in combination with metformin, sulfonylureas, acarbose, micolitol, insulin, etc., without increasing the risk of hypoglycemia.