Congenital deafness is genetic, what should I do 50

1 Autosomal dominant inheritance.

If one of the parents is sick, the sick parent is heterozygous, and the child has a 1 2 chance of getting the disease; The sick party is homozygous, and the child is 100% sick; If both parents are deaf and heterozygous, the child has a 3 4 chance of getting sick and 1 4 is normal. However, if the child does not get the disease, the child's offspring will not get the disease again, so the child will no longer have the disease gene in the child.

2 Autosomal recessive inheritance.

Assuming that both parents have a normal phenotype, but both carry the genes that cause deafness and mute and both pass on to the next generation, a deaf child will be born with a chance of 1 4;However, if only one party passes on the deaf-mute gene to the next generation, the offspring will become a carrier of the deaf-mute gene and will not cause disease, with a probability of 1 2;If none of the disease-causing genes are passed on, the offspring will be healthy without disease-causing genes, and the probability is 1 4.

If both parents are born with hereditary deafness and mute, and the allele is genetic, the child born is deaf and mute, regardless of gender. In this case, fertility is not allowed.

If one of the parents is born with hereditary deafness, and all the children born are normal children (but they are carriers of the deaf-mute gene), this is calculated according to the law of heredity.

If one of the parents is a carrier of the deaf-mute gene, none of the children will have the disease, but there is a 1 2 chance of becoming a carrier of the deaf-mute gene and a 1 2 chance of becoming a normal person without the deaf-mute gene.

In practice, children are less likely to be sick than theoretical. For example, because deaf-mute patients often marry deaf-mutes because it is difficult to find a partner, if most of them are estimated by autosomal recessive inheritance, their children should all be deaf-mute, but the actual survey results show that about 70 children do not develop the disease, which is due to the fact that most of the parents carry non-allelic recessive genes, so there is a phenomenon of double heterozygous without disease.

3 X-linked (sex chromosome-linked) inheritors and polygenic inheritance.

X-linked inheritance is rare (less than 2) and is usually not inherited in females (unless homozygous), and in males, it is even rarer in females, and the offspring is inevitably invariably diseased. Since the information provided by the counselor is that his mother is deaf and mute, and that his brother is a normal person, X-linked inheritance can be ruled out. As for polygenic inheritance, it cannot be simply analyzed, generally speaking, as long as both parties are normal people, the offspring should generally be normal.

If you are pregnant, you can investigate and deal with it through chromosome testing, and the general genetic testing will take about 100 yuan, and the results will be available in about 10 days.