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The characteristics of the receptor include specificity, sensitivity, saturation, reversibility, and variety field detection.
A receptor is any biological macromolecule that binds to hormones, neurotransmitters, drugs, or intracellular signaling molecules and causes changes in cellular function. According to the location of the receptor in the cell, it is divided into two categories: cell surface receptors and intracellular receptors.
The receptor itself contains at least two active sites: one that recognizes and accompanies the trapped ligand; The other is the functionally active site responsible for the production of the response response, which can only produce a response when it binds to the ligand to form a binary complex and is allosteric, thereby initiating a series of biochemical reactions that eventually lead to the biological effects of the ashwagandha cells.
Most ligand signaling molecules are hydrophilic biological macromolecules, such as cytokines, protein polypeptide hormones, water-soluble hormones, prostaglandins, hydrophilic neurotransmitters, etc., because they cannot penetrate the target cell membrane into the cell, therefore, the receptor of this kind of ligand signaling molecule is located on the target cell membrane.
The receptor for most ligand signaling molecules is on the surface of the target cell because the signaling molecule is hydrophilic and cannot pass through the cell membrane. However, there are some ligand signaling molecules that can directly cross the target cell membrane, interact with the cytoplasm or nuclear receptor, and use the expression of gene expression products to up-regulate or down-regulate by regulating the transcription of specific genes, thereby initiating a series of biochemical reactions.
Function of the receptor:
The first function is to recognize and bind to signaling molecules (ligands) that are specific to themselves. It is through the recognition of receptors and signaling ligand molecules that cells can recognize and receive a specific signal in an environment filled with countless biomolecules.
The second function is to amplify and transmit the recognized and received signals to the inside of the cell with unmistakable accuracy, thereby initiating a series of intracellular signaling cascades that lead to specific cellular biological effects.
The result of binding between the receptor and the ligand is that the receptor is activated, and the basic steps of subsequent signaling are generated by the receptor activation. Under physiological conditions, the binding between receptors and ligands is not mediated by covalent bonds, and is mainly bound to each other by ionic bonds, hydrogen bonds, van der Waals forces, and hydrophobic. When the receptor binds to the ligand, it has the characteristics of saturation, high affinity, specificity, and reversibility.
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In April 2005, he took the 4th question of the noun explanation of the real question of "Physiological Psychology Scattered Staring" in Beijing.
Receptors:It is a special skin digging protein molecule on the cell membrane, which can recognize and selectively react with specific receptors of certain substances to produce corresponding biological effects. Substances that can bind to receptor proteins, such as trace neurotransmitters, modulators, hormones, and drugs, are collectively referred to as receptor ligands or ligands.
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The common characteristics of receptors are saturation with ligands, specificity with ligands, reversibility with ligands, high affinity and diversity of effects with ligands.
Receptors, also known as receptors and receivers, are a biochemical concept that refers to a class of molecules that can conduct extracellular signals and produce specific effects within cells. Receptors are present in cell membranes, cytoplasm, or nucleus, and their effects may last only for a short period of time, such as altering cellular metabolism or cell motility, or they may be long-term effects, such as upregulating or downregulating the expression of one or more genes.
Receptors pharmacologically refer to biological macromolecules composed of glycoproteins or lipoproteins, which exist in the cell membrane, cytoplasm or nucleus. Different receptors have specific structures and configurations. Receptor is a broad concept in cell biology, which refers to any biological macromolecule that binds to hormones, neurotransmitters, drugs, or intracellular signaling molecules and can cause changes in cell function.
The main characteristics of the receptor:
The specificity of receptor-ligand binding is the most basic feature of the receptor, which ensures the correctness of signal transduction. The binding of ligands and receptors is a molecular recognition process, which relies on the action of hydrogen bonds, ionic bonds and van der Waals forces to bind them, and the complementarity of the molecular spatial structure of ligands and receptors is the main factor of specific binding.
In addition to the fact that one receptor can only bind to one ligand, specificity can also be understood to mean that there may be two or more different receptors for the same ligand in the same cell or different types of cells; Binding of the same ligand to different types of receptors produces different cellular responses, for example, epinephrine acts on the receptors on the mucosal blood vessels to cause the vascular smooth muscle to contract, and the receptors on the bronchial smooth muscle to relax it.
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Receptor () aIt is formed and inherited during the evolution of organisms.
b.In the body there are specific points of distribution in the mammoth.
c.The number is unlimited, so there is no saturation.
d.Receptors distributed in each organ have different sensitivities to ligands.
e.It is a complex protein molecule that can be metabolized.
Correct Answer: It is formed and inherited during the evolution of organisms; There are specific points of distribution in the body; The receptors distributed in each organ had different sensitivities to ligands. Laughter is a complex protein molecule that can be metabolized.
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