How does obesity work? How obesity is formed

Obesity is not just due to eating too much and moving less, there are other reasons, if you are not sure, it is good to consult a doctor.

Eat more, consume less, consume too much energy:

There are a variety of causes and pathophysiological mechanisms that lead to excessive fat accumulation in the body. Obesity is simply the result of energy imbalance, energy intake comes from the digestion and absorption of food, and the energy consumption in the body includes the maintenance of vital metabolism and physiological functions at rest, as well as for work and other physical activities. When energy intake exceeds energy expenditure, excess calories are stored in adipose tissue as fat, and weight gain is gained, so there are basically two factors that lead to obesity

One is eating too much, and the other is consuming too little.

Genetic factors: obese people often show familial, that is, the parents are obese and obese since childhood, in the laboratory animals, the genetic factors of obesity are clear, such as an obese rat (ob ob) has a basic defect in the constitution of thermogenesis, resulting in fat can not be consumed, so it presents the characteristics of obesity. In humans, identical twins are also often obese at the same time, and some of them who have been raised in different families since childhood also show the same symptoms, so genetic factors are certain.

Genetic factors may increase the appetite of obese people through the influence of the central nervous system, or they may affect the excessive accumulation of fat after the obese person absorbs food, or the amount of daily activities.

Environmental factors: Obesity can be caused by reducing the amount of exercise or increasing appetite for certain reasons, but only a very small number of cases are actually caused by diseases.

Damage to the nucleus in the hypothalamic ventricle:

Animal experiments have proved that the nucleus of the hypothalamus ventricle is the satiety center of animals, and when this part is damaged, it will lead to overfeeding, rapid weight gain and obesity, and the other is the feeding center in the center of the nerve center, if it is damaged, it will cause anorexia and refusal to eat, and the weight will also remain low.

Light concentration: In recent years, scientists have found that animal fat cells will secrete a protein hormone called leptin, its concentration will directly affect the behavior of eating, the more fat cells, the more light secretion, the less food will be eaten, in order to regulate the weight of the body. There is evidence that some obese people have problems with the light receptor or structure of the light pigment that affects this feedback system and forms obesity.

Obesity may be due to genetic causes, dietary reasons, or it may be due to inactive exercise, so fat accumulates and forms obesity.

Obesity is mostly caused by eating too many calories to be metabolized through physical exertion, and the excess calories are converted into fat and stored in the subcutaneous tissue. When the weight exceeds 20% of the normal standard, it is considered obese There are two ways to calculate the normal value: height (cm) -100 (1 10%); By the usual standard, the body mass index ( is equal to the square of weight in kilograms divided by height in meters), which is between normal weight and to overweight, and above is obese.

Obesity can lead to many diseases. If only the various diseases related to obesity are not carried out on the obesity itself, then the effect will not be very satisfactory, and the cost will be very high. The following diseases are all associated with obesity and are the basis of these diseases.

Hypertension The most common comorbidity of obesity is hypertension. 30% of people who weigh more than 15 kg of the standard body weight suffer from high blood pressure. The increase in blood pressure is associated with some vasoactive substances secreted by fat cells and is also associated with insulin antagonism.

Mild hypertension returns to normal with weight loss and reduced salt intake, and antihypertensive drugs can be dispensed with**. Hypertension is an important risk factor for cardiovascular and cerebrovascular diseases, and if not timely**, it will lead to serious consequences.

Diabetes Obesity is closely related to diabetes, and the type of diabetes referred to here is type II diabetes. The general belief is that when obesity reaches a certain level, peripheral tissues (mainly muscle and fat) are insensitive to insulin, i.e., insulin antagonism. The pancreatic islets compensately secrete more insulin to counteract this antagonism to insulin, resulting in hyperinsulinemia.

After about a few years to decades, the overworked islets fail and diabetes develops. Of course, after diabetes, it is the foundation of diabetes.

Cancer Obese patients are more likely to develop cancer. The risk of breast, uterine and cervical cancer increased by 3 times and the risk of endometrial cancer increased by 7 times in obese women. Obese men also have a significantly increased risk of colon and prostate cancer.

Hyperlipidemia Most obese patients have lipid metabolism disorders, hypercholesterolemia, hypertriglyceridemia, etc. The causes of hypercholesterolemia include genetics and dietary effects, and in general, **** can normalize blood lipids.

Other obese patients have a short life expectancy, and the average life expectancy will be shortened by 1 month for every 1 kg of body weight gained in addition to the standard body weight in the overall population. Obese patients are prone to heart accidents and strokes, nearly 30% of obese patients suffer from gallstones, and obese patients are also prone to degenerative osteoarthropathy and sleep apnea syndrome. Obesity often leads to arthritis, asthma, breast cancer, colon cancer, and heart disease.

How obesity is formed, just pay attention to these points, and say goodbye to obesity!