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One base is added, and the gene must have changed, yes.
Biological traits do not necessarily change The same amino acid can have multiple codons (conjugation).
If you don't participate in the synthesis of amino acids, it will be impossible to change the trait.
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As we all know, if one base is added, the gene must be changed" There is a loophole in this sentence. If the base is not added to the gene, such as most of the non-coding regions, it is generally fine. If it is added inside the gene, in the upper part of the gene's coding sequence, it is very likely to change the protein it encodes, and it may not affect it at the end (the core region of the protein is not destroyed).
In addition, if the gene does not exhibit a phenotype or other genes can be replaced, then the biological trait will not be changed.
The tail of mRNA is not synthesized according to the sequence on the template of DNA, it is a polya tail, and it is basically fine to add a base.
The concept of landlord is not clear, and it is recommended to learn more about the basics.
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Won't happen: 1When a gamete or zygote is formed, it mutates back again.
The odds are extremely unlikely. 2.Although there is a mutation of one base, the codon before and after the mutation is translated into the same amino acid, and the progeny does not change.
3.The mutated base is in the region where it is not expressed. Not comprehensive.
In addition to genotype, progeny traits are also related to environmental factors.
That's great, you can try it.
S disease S S Illness S Illness S S Illness S S Sqd h gm wave |36628508142011-9-12 19:35:45
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Classmates, that's called gene mutations, not base mutations, gene mutations are divided into addition, deletion, and change, and addition and deletion generally cause greater trait changes, because the order of a strand has changed (of course, it may be a non-coding region, it's fine, if it's the start codon, the whole chain has changed, if the stop codon translation won't end, it's all dangerous, and a bunch of them are all major diseases), if it's an in-situ change, if it's a different codon that controls the same AA, then the trait won't change, If the codons of different AAs are synthesized, this will change (e.g., sickle hemocytosis).
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The answer is no.
First, if the mutation occurs in the intron of the base mill and the sequence is not present in the mature mRNA, it is very likely that the trait will not change.
Secondly, due to the early degenerate of codons (the phenomenon that several codons can encode an amino acid), after a base mutation, its amino acids may remain unchanged, so that the traits will not change.
In addition, the amino acids that can synthesize proteins can be divided into several categories, among which some amino acids are very similar in nature, and these amino acids have little or no effect on the properties of the whole protein after being exchanged.
Finally, even if the nature of the mutated gene product (protein) changes, there may be a situation where there are multiple copies of the gene in the organism, and if there is a problem with one gene, other genes can still maintain the relevant function by supplementing the deficiency.
This is a self-protection mechanism for organisms against undesirable mutations. In fact, the vast majority of mutations are undesirable mutations, and changes in biological traits are mainly dependent on genetic recombination (i.e., sexual reproduction).
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Not necessarily, some gene mutations only change some bases, such as uua mutation to uug, there is a base change, but the encoded protein is still leucine, so gene mutations do not necessarily lead to changes in biological traits.
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Not necessarily. Because there are many kinds of codons that control the same protein.
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Not necessarily, dominant mutations, introns on DNA, non-coding regions, environmental influences, etc., do not necessarily alter the trait.
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Not necessarily, for example, AA mutations to AA
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There are several reasons why genetic mutations do not necessarily cause changes in biological traits:
1. The base of the gene mutation is located in the non-coding region of the gene structure or occurs in the intron of the eukaryotic gene structure, and the messenger RNA of the gene transcription of this gene remains unchanged (but the precursor RNA changes), so the synthesized protein does not change, and does not cause changes in biological traits.
2. Since a variety of codons determine the same amino acid, some gene mutations do not cause changes in biological traits. For example, uuu and uug are both codons of phenylalanine, and when u and g are replaced by each other, the function of the codon is not changed, because it is phenylalanine that determines the amino acid.
3. Although some mutations change the types of individual amino acids in the protein, they do not affect the function of the protein. For example, due to genetic mutations that alter the amino acids in cytochrome C in different organisms, where the seventeenth position of the cytochrome C peptide chain of yeast is leucine, while wheat is isoleucine, despite such differences, their cytochrome c functions are the same.
4. Functional mutations of recessive genes will not cause changes in traits in the heterozygous state, for example, in peas, tall stem gene D is dominant to short stem gene D; If there is a D mutation in a zygote with genotype DD, the zygote has a genotype of DD, but the trait cannot be expressed in the heterozygous state of the dwarf stem gene.
5. Due to the polygenic determination of traits, a certain gene is changed, but other genes that act together on this trait are not changed, and their traits will not change. For example, the inheritance of the color of the corolla of fragrant peas.
When C and R are present at the same time, they show safflower, and when they are not present at the same time, they do not appear red. Therefore, when mutating from CCRR to CCRR, it does not cause a change in traits.
6. Trait performance is the result of the joint action of genetic and environmental factors, and under certain environmental conditions, the changed genes may not be manifested in traits. For example, if the pea of DD mutates to DD, it should have a mutation of a stem, but if it is planted in poor soil, it will grow into a short stem and will not mutate.
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Gene mutation refers to the addition, deletion, and change of base pairs, etc., biological traits are determined by proteins, and proteins are determined by genes, a protein can be determined by several base pairs, so gene mutations do not necessarily cause changes in biological traits!
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Because an amino acid is controlled by a codon composed of 3 bases, a gene mutation is a base change, and an amino acid can be controlled by a variety of codons, so the base change does not necessarily cause the amino acid change, so the protein does not necessarily change, so the gene mutation does not necessarily cause a change in biological traits. Hope to adopt, thank you.
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Occurs in highly differentiated somatic cells.
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Genetic mutations refer to sudden, heritable mutations in genomic DNA molecules. At the molecular level, a gene mutation is a structural change in the composition or order of base pairs.
Gene mutation is a change in the structure of a gene caused by the addition, deletion or replacement of base pairs in a DNA molecule, which is called a gene mutation.
If a "substitution" of base pairs occurs in a gene, it does not necessarily cause a change in the trait. There are three main reasons:
1) The mutation site may be in the non-coding site (intron and non-coding region).
2) The codon formed after the gene mutation and the protocodon determine the same amino acid.
3) If the gene mutation is a recessive mutation, it will not lead to a change in the trait.
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