What are the side effects of Zolodine, the worst side effects of Metrodine

Zolodine is a more common drug that will make the user feel nauseous, and extravertebral reactions, some patients are difficult to overcome this nausea after taking it, and it is difficult to deal with this sequelae. And because there are individual differences in the patients taking the drug, the patient's feedback on the drug should be listened to, so that the doctor is right.

If it is caused by the drug, it will recover after stopping the drug, which is reversible. If it is caused by the disease, it is irreversible to discontinue the drug.

Xuzhou Oriental People's Hospital - Department of Psychiatry - Deputy Chief Physician Jin Zibin.

As you get older, you will be more susceptible to Alzheimer's disease than normal people, and your heart will be affected.

Hello glucocorticoids, mainly: affect metabolism, raise blood sugar; altered fat distribution, resulting in buffalo back, full moon face; water retention and permissive effect, raising blood pressure; Promotes protein breakdown, muscle atrophy; Decreased potassium and calcium reabsorption, leading to hypokalemia and osteoporosis; Affects the blood system, increases white blood cells, red blood cells, hemoglobin, platelets, and decreases lymphocytes and eosinophils; suppression of immune function, inducing or aggravating infection; When used in large doses, it can induce or aggravate peptic ulcer.

Your son's condition 1, may be related to fat distribution, full moon face; 2. Protein decomposition, muscle atrophy, fatigue; 3. It can cause elevated white blood cells; 4. It is normal for children to have sinus arrhythmia, if not, hormones are not easy to cause; 5. It can cause emotional instability, irritability, insomnia, etc.

Tapering slowly, relieved when discontinued.

Metro (methylprednisolone) is a synthetic glucocorticoid, *** which is basically the same as prednisone (prednisone) except for the liver.

The following should be avoided while taking Metsola***:

1. Concurrent or aggravated infection: it is more common in people with severe disease and weak constitution. The more common infections are respiratory, **, urinary tract infections and tuberculosis, etc.

Once there are signs of infection, a strong antimicrobial drug should be used to control it promptly. In addition, high doses of corticosteroids can cause an increase in white blood cells, sometimes up to 20 109 L, so do not overdiagnose infection alone.

2. Cause water and electrolyte imbalance: large doses of hormones can cause diuretic effect. However, at the beginning, hormones still fail to exert a diuretic effect, but can cause water and sodium retention, aggravating edema, at this time, if necessary, diuretics should be used at the same time, and a low-salt diet should be carried out.

Hormones can sometimes worsen or cause high blood pressure and should be lowered**. After the occurrence of diuresis, attention should be paid to the possibility of hypokalemia, and the patient should be advised to eat potassium-rich foods appropriately, or to take potassium-sparing diuretics in combination, and if hypokalemia still occurs, potassium salt can be appropriately supplemented. Hormones can increase the excretion of calcium and phosphorus, reduce the absorption of calcium, and long-term use in large quantities can cause osteoporosis, spontaneous fractures and aseptic necrosis of the femoral head, which should be noted.

3. Neuropsychiatric symptoms: it can cause agitation, insomnia, and psychosis, and can appropriately use sedatives such as diazepam.

4. Inhibition of growth and development: seen in children with long-term use of hormones. However, if prednisone 10 mg per day is used, it usually has little effect on growth.

5. Similar to adrenal hyperfunction: such as central obesity, moon face, acne, hirsutism, weakness, susceptibility to infection, hypokalemia, edema, hypertension, diabetes, etc. Regarding the Kirchen-like state, there is no need for **, it will decrease or even disappear with the withdrawal of hormone dose.

Hormones can promote protein decomposition and inhibit its synthesis to cause negative nitrogen balance, so it is advisable to give a high-protein diet, some patients originally had mild azotemia, aggravated after hormones**, and even kidney failure, it is advisable to stop the drug; Hormones promote gluconeogenesis and reduce tissue utilization of glucose, and in severe cases, hyperglycemia and glycosuria may occur, but ketoacidosis generally does not occur, and corticosteroids are usually not discontinued**. Diet or insulin injections can be controlled according to the condition, usually starting with 10 units of subcutaneous injection.

6. Long-term use of hormones can still induce cataracts, glaucoma, poor wound healing, thrombosis and embolism, excessive sweating and night sweats, as well as menstrual disorders.

Metro Methylprednisolone Metrol (methylprednisolone tablets) belongs to the glucocorticoid class of drugs and has powerful anti-inflammatory effects. So what exactly does Metrola do? What are the main indications?

1.systemic lupus erythematosus and lupus nephritis); systemic dermatomyositis (polymyositis); acute rheumatic myocarditis; polymyalgia rheumatica; giant cell joints; 2.Pemphigus; bullous dermatitis; exfoliative dermatitis; mycosis; severe psoriasis; severe seborrheic dermatitis; 3.

seasonal or year-round allergic rhinitis; serum sickness; bronchial asthma; allergic reactions to drugs; contact dermatitis; atopic dermatitis; 4.Severe acute and chronic ocular allergies and inflammation involving the eye and its appendages, e.g., allergic corneal margin ulcers; ocular herpes zoster; anterior eyelash infection, diffuse posterior chamber pigmentitis and choroiditis; Sympathetic ophthalmia.

allergic conjunctivitis, keratitis, chorioretinitis; optic neuritis; iritis, iris, cyclitis, pulmonary sarcomatosis; 5.Loffler's syndrom not controlled by other methods in combination with appropriate anti-tuberculosis** for fulminant or diffuse tuberculosis; It is used for diuresis and proteinuria relief in spontaneous or lupus nephrotic syndrome without uremia. 6.

ulcerative colitis; localized ileitis; Acute critical phase of multiple sclerosis; Control of edema caused by brain tumors. Metro has a good anti-inflammatory effect on acute rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis and other rheumatic diseases.

Mesora methylprednisolone tablets

Metro methylprednisolone tablets are able to be used for rheumatic diseases, collagen diseases, ** diseases, allergic states, eye diseases, respiratory diseases, edema states, diseases of the gastrointestinal tract, nervous system, in combination with appropriate anti-tuberculosis**, organ transplantation. So?

Methora methylprednisolone tablets are hormonal drugs, methylprednisolone is a synthetic glucocorticoid. Glucocorticoids diffuse through cell membranes and bind to specific receptors in the cytoplasm. This conjugate then travels into the nucleus to bind to DNA (chromosomes), initiating transcription of mRNA and the synthesis of various enzyme proteins, through which systemic glucocorticoids are thought to exert multiple effects.

Glucocorticoids have important effects not only on inflammatory and immune processes, but also on carbohydrate, protein, and fat metabolism, and also on the cardiovascular system, bone marrow and muscular system, and the central nervous system.

Glucocorticoids have the effect of breaking down proteins, and the released amino acids are converted into glucose and glycogen in the liver through gluconeogenesis. Glucose absorption by peripheral tissues decreases, leading to elevated blood glucose and diabetes, especially in patients with a predisposition to diabetes.

Glucocorticoids have the effect of breaking down fats, which mainly affect the limbs; In addition, glucocorticoids have a fat-synthesizing effect, which is especially pronounced in the chest, neck and head. All this leads to a redistribution of fat.

The maximum pharmacological effect of corticosteroids occurs after the peak blood drug concentration, suggesting that most of their effects are initiated by altering enzyme activity rather than the direct effect of the drug.

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Adverse reactions:

1.Fluid and electrolyte imbalances.

Sodium and water retention (edema, hypertension, congestive heart failure in some sensitive patients), hypokalemia, hypokalemia alkalosis.

2.Musculoskeletal system.

Osteoporosis, aseptic necrosis of the femoral head, pathological fractures, muscle weakness, steroid myopathy.

3.Gastrointestinal tract.

Peptic ulcer, bleeding or perforated ulcer, pancreatitis, esophagitis.

4.**。**Brittleness, petechiae, purple spots, delayed wound healing.

5.Metabolism. Negative nitrogen balance due to protein breakdown.

6.Nervous system.

Elevated intracranial pressure, pseudotumor brain tumor, confusion, and seizures7Endocrine system.

Menstrual disorders, Kirshing's disease, inhibition of the pituitary-adrenal axis, decreased glucose tolerance, underlying diabetes, increased need for insulin and oral hypoglycemic drugs in diabetic patients, and growth suppression in children.

8.Posterior subcapsular cataract, increased intraocular pressure, and proptosis9Immune system.

Mask infection, cause potential infection, complicate opportunistic infection, allergic reaction, and suppress test reaction.

Contraindications: patients who are allergic to glucocorticoids and systemic fungal infections.

Normal people take this medicine is not normal, first of all, drowsiness, this medicine is to inhibit the secretion of dopamine, high school science students are clear, dopamine is a neurotransmitter, no dopamine, people are a mess of meat, no dopamine, cells can not communicate, the serious consequences are that the heart stops beating, not serious, that is, it is a normal person, but it is considered abnormal by others, because there is no dopamine, people will always want to sleep, eat for a long time, more likely than normal people Alzheimer's, the heart is worse than normal people, and the lungs are too.

Medola is the brand name of the drug, which is prednisolone, which is also a type of hormone.

Guidance: Taking Mezola will also have the same as other hormones***, involving the digestive system, bone system, metabolic system, etc. However, if the medicine is used rationally according to the doctor's instructions, it can be minimized.

The principle of the drug is to control and reduce dopamine, dopamine is the communication substance of human cells, your nerves rely on dopamine to conduct information, after a long time, your nerves will be sick, the most direct symptom, you may be a little earlier than other people who do not take this drug Alzheimer's, and his *** is not only this, as long as it is related to the nerve, there will be diseases, and your heart will also be affected, because he is an autonomic nerve.

It is a normal reaction, and there will be a certain amount of tremor when using this drug, which is caused by the extrapyramidal reaction of the drug, so don't worry.