Can you take sodium levothyroxine tablets while taking sofosbuvir

pharmachologic effect. Sofobuvir is a direct-acting antiviral drug that inhibits the RNA-dependent RNA polymerase, the NS5B gene, for hepatitis C virus (HCV). The ns5b gene is essential for hepatitis C virus replication.

Drug interactions.

1. Severe symptomatic bradycardia may occur when amiodarone, sofosbuvir and antiviral drugs (DAA) are combined. 2. Strong intestinal P-GP-inducing drugs (e.g., rifampicin, St. John's wort) may change the concentration of sofosbuvir.

Adverse effects. The most common known adverse reactions (incidence equal to or greater than 20%, all grades) caused by sofebuvir plus ribavirin are headache and fatigue; The most common known adverse effects of sofibuvir plus peginterferon and ribavirin include fatigue, headache, nausea, insomnia, and anemia.

Medication for special populations.

HCV HIV-1 co-infected patients: The safety and efficacy of this drug have been confirmed by studies.

Hepatocellular carcinoma patients awaiting liver transplantation: the safety and efficacy of this drug have been confirmed by studies.

The drug is available in the UK and the US, but not yet in China, and domestic customers who want to buy the drug can seek help from large US pharmacy chains such as Haoeyou Pharmacy.

Contraindication. When used in combination with peginterferon- + ribavirin, or in combination with ribavirin, all contraindications for peginterferon- and or ribavirin also apply to sofosbuvir in combination with **.

Because ribavirin has the potential to cause congenital malformations or stillbirth, sofosbuvir plus peginterferon + ribavirin, or sofosbuvir alone plus ribavirin should be used in pregnant women and men whose partners are pregnant.

Precautions. 1. Bradycardia caused by combination with amiodarone: patients using sofosbuvir combined with antiviral drugs (DAA) combined with **CHC may develop severe symptomatic bradycardia if they take amiodarone at the same time, especially in patients who are using concurrent -receptor blockers or have potential cardiac complications and advanced liver disease.

2. Pregnancy: ribavirin may cause congenital malformations or stillbirth, and animal experiments have shown that interferon can cause miscarriage. Therefore, women taking this medicine and spouses of men should avoid pregnancy.

Patients must have a negative pregnancy test, use at least two non-hormonal methods of contraception, and undergo monthly pregnancy tests prior to initiation** [2].

This is not a conflict with the Indian medicine that can be brought to people in India.

The price of yao in India is low, and relatives are using it.

There is no one in this country at the moment , I used to buy it through Hangzhou Wuzhou , and I also arranged a long-distance consultation , which was sent directly to my home from India , which is very convenient . It will be a time to get left and right in a week, and you can ask them anything .

Hangzhou Wuzhou t e l: ( 4 0 0 - 1 5 0 - 8 0 8 9).

Sofosbuvir, preferably an hour after dinner, you can rest after eating, so that there are individual ***.

Sophie is used for 6 genotypes of hepatitis C. The second generation is only suitable for types 1, 4, and 6

Available in two drugs, sofosbuvir and daclatasvir, currently has a rate of up to 90% for hepatitis C. Please consult your doctor for specific use.