What happens if you don t get enough sleep for a long time, and what happens if you don t get enough

Sleep time accounts for one-third of people's lives, and only when you get enough sleep can you be energetic and study efficiently. Relevant medical experts pointed out that lack of sleep has become a major killer of human health! From a health perspective, sleep deprivation can be harmful.

Because if people often stay up late, they are most likely to get tired and lose energy, and the body's immunity will also decline. Colds, gastrointestinal infections, allergies, and more will come to you. If you don't get enough sleep for a long time, you will gradually develop neurological and psychiatric symptoms such as insomnia, forgetfulness, irritability, and anxiety.

Overwork causes the nervous system of the body to malfunction, causing imbalance in the main organs and systems of the body, such as arrhythmia, endocrine disorders, etc., which will lead to a state of stress in the whole body and a corresponding increase in the probability of contracting diseases. People with strong fatigue symptoms are also more likely to suffer from various infections such as the respiratory, digestive, and circulatory organs than the general population. Sleep experts believe that

Sleep is an important physiological process in metabolic activity. Without sleep, there is no health, and lack of sleep will not only not be replenished by the body's consumption, but also cause imbalance in the internal environment due to insufficient hormone synthesis. After a series of studies on sleep and human immunity, immunologists in the United States believe that sleep can not only eliminate fatigue, but also have a close relationship with improving immunity and the ability to resist diseases.

People who get enough sleep have a significant increase in T lymphocytes and B lymphocytes in their blood, which are the main force of immunity in the body. Drowsiness is a sign of considerable brain fatigue and should not wait until this time to go to sleep. Only by developing the habit of sleeping regularly and ensuring that the sleep time is not less than 7 hours a day can the normal operation of the sleep center biological clock be maintained.

Therefore, young people should also learn to control their living habits and not let the natural rhythm be disrupted and fall into a vicious circle. People who often work or study overtime at night should eat more protein-rich foods such as fish and milk, and take health products containing lecithin, brain cell growth factor, tuna oil, taurine and other ingredients in moderation to supplement brain power; If you have a headache, you can take Antelope Horn Drop Pills to relieve symptoms.

Humans spend a third of their lives sleeping, including invertebrates such as flies, worms, and even jellyfish. Throughout evolution, sleep has been universal and essential for all organisms with a nervous system. However, have you ever wondered why we sleep?

In fact, scientists have been searching for answers for years. According to a new study published in the journal Molecular Cell on November 18, researchers at Bar-Ilan University in Israel have found that the PARP1 protein in the brain acts as an "antenna" that sends time signals to the brain to sleep and repair DNA damage, a discovery that is one step closer to solving this mystery.

When we are awake, the homeostatic sleep pressure in the body increases, and the longer we stay awake, the more stress this stress increases. During the few hours of waking hours, factors such as ultraviolet light, neuronal activity, radiation, oxidative stress, etc., can cause sustained DNA damage in neurons. However, excessive DNA damage in the brain can be dangerous, and sleep can "summon" the DNA repair system.

The characteristics of neural activity during sleep in zebrafish are similar to those of humans, and they are the subjects of sleep study. Through zebrafish experiments, researchers determined that the accumulation of DNA damage is a driving factor that causes sleep states. When the accumulation of DNA damage reaches the maximum threshold, the homeostatic sleep stress increases to the point where the urge to sleep triggers it, and the fish goes to sleep.

Subsequent sleep promotes DNA repair, which reduces DNA damage.

So, what are the mechanisms in the brain that tell us: where is it time to sleep? It was found that the PARP1 protein is part of the DNA damage repair system and is one of the first proteins to respond to rapid reciprocal reciprocation.

It flags the location of DNA damage in the cell and "recruits" all relevant systems to remove the DNA damage.

Through genetic and pharmacological manipulation, overexpression and knockdown (down-regulation) of PARP1 experiments have shown that increasing PARP1 not only promotes sleep, but also increases sleep-dependent repair. Conversely, inhibition of PARP1 blocks the signal for DNA damage repair. As a result, the fish are not fully aware that they are tired and therefore do not go into sleep mode, causing DNA damage to not be repaired in time.

The same results were validated in mice.

This new finding describes how to explain the "chain of events" of sleep at the single-cell level. This mechanism explains the link between sleep disorders, aging, and neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. The researchers believe that future research will be extended to more animals, from lower invertebrates to humans.

Long-term lack of sleep will lead to many problems in patients, such as malaise, sleepiness, and lack of concentration during the day, and long-term insomnia will lead to memory loss and resistance decline in patients, and they are prone to colds and pneumonia.

After a long period of insufficient sleep, women will cause endocrine disorders and lead to menstrual disorders, and the patient's ** will appear dull and dull. If the elderly have high blood pressure, heart disease, diabetes and other diseases, long-term poor sleep will adversely affect the control of these diseases. Therefore, patients with long-term sleep deprivation must be adjusted in time, from the aspects of lifestyle, psychological state, and medication.

1. Decline in nervous system function: long-term lack of sleep will lead to brain fatigue, energy can not be recovered, affect work efficiency, lead to memory decline, manifested as inability to concentrate, slow response, and may also produce expression disorders, etc., may also affect mood, irritability, irritability, etc.;

2. Decline in circulatory system function: long-term lack of sleep will lead to increased burden on the heart, long-term fatigue, decreased heart pumping function, resulting in hypoxia of body tissues, arrhythmia, angina, and even myocardial infarction;

3. Deterioration of physical fitness: long-term lack of sleep will affect physical fitness, causing the body to be susceptible to bacterial infections, and may have colds and other conditions;

If you sleep four hours a day, it is definitely not enough, long-term lack of sleep has a certain impact on the body, may affect the normal development of the body, brain thinking, etc., and may also induce diseases, such as upper respiratory tract infection, neurasthenia, etc.

1. Affect the normal development of the body.

In general, the human body secretes auxin during sleep, but less during sleep. If the patient has a long-term lack of sleep, it will affect the normal development of the body.

2. Affect the brain's thinking.

For some people, long-term sleep deprivation may also affect the brain's thinking clarity and brain responsiveness, and it is easy to have inattention, dizziness, memory loss, etc., and some patients may also have headache symptoms.

3. Induce disease.

Lack of sleep will reduce the body's immunity, and it is also prone to anxiety and other bad emotions, which may induce diseases such as upper respiratory tract infections and neurasthenia, and even increase the risk of heart disease, diabetes and other diseases, which need to be paid attention to.

In addition to the above, long-term sleep deprivation may also increase melanin production, affecting metabolism. It is recommended to develop good sleep habits and ensure adequate sleep time to reduce the impact on health and quality of life.

The effects of long-term sleep deprivation: first, it leads to neurasthenia, and the efficiency of work and study is greatly reduced; Second, if it is a teenager before the age of 18, it will also affect growth and development, resulting in development delay; Third, women's lack of sleep for a long time also affects endocrine function, leading to menstrual disorders, premature ovarian failure, and even affecting fertility, and men will also affect sexual function, resulting in impotence or**; Fourth, long-term sleep deprivation can induce cerebrovascular diseases; Fifth, long-term lack of sleep can lead to a decrease in the body's immunity, and can even cause neoplastic diseases.

1. Decreased immunity.

A study by Carnegie Mellon University in the United States found that sleeping less than 7 hours a night can damage the immune system, causing colds to increase by 3 times.

2. It is easy to become ugly.

Lack of sleep is easy to have a dull complexion, lose a lot of charm, and lose affinity. A study by the Karolinska Institutet in Sweden has found that lack of sleep accelerates aging.

3. Easy to become stupid.

A study published in the American journal Sleep found that a night of sleep deprivation led to a decrease in brain tissue, which is the same as the increase in blood tests of both brain molecules after brain injury.

4. Easy to overeat.

Several studies have shown that people with short-term sleep deficits are more likely to overeat, prefer to eat high-calorie, high-carbohydrate foods, and eat more greasy.

5. Increase the risk of car accidents.

The American Sleep** Association study published in the American Journal of Prevention found that less than 6 hours per night can lead to a three-fold increase in the risk of car accidents. The main reasons include lack of sleep, which can affect the coordination of the eyes and the dexterity of the hands and feet.

6. Emotional out-of-control.

A study by scientists from the University of California, Berkeley, and Harvard Medical School found that a night of sleep deprivation led to more active brain areas responsible for emotional management, suggesting that sleep deprivation is more likely to lose control of emotions.