Is metformin the best hypoglycemic drug? Are there any other medicines?

Updated on healthy 2024-05-01
26 answers
  1. Anonymous users2024-02-08

    At the moment, it is indeed the best, and nothing better than this has been found, when it comes to oral hypoglycemic drugs, diabetes doctors and sugar friends will first think of metformin. Metformin is the traditional medicine for diabetes. In recent years, metformin has been positioned as the first line drug for type 2 diabetes mellitus in international and Chinese guidelines for the diagnosis and treatment of diabetes, and it is recommended as the only drug that can be used in combination with other oral drugs and insulin throughout the diabetes process.

    1. The importance of knowing himAccording to the latest news I have learned, metformin has become the most commonly used hypoglycemic drugbecause it has been published for more than 50 years, has extensive clinical use experience, and has the fullest evidence of clinical benefit. Its landmark British prospective diabetes study, UKPDS, confirmed that metformin is the only glucose-lowering drug that can reduce macrovascular complications and reduce complications and mortality from type 2 diabetes, and that metformin has no significant effect or slight weight loss in patients with type 2 diabetes.

    Second, we need to pay attention when usingHowever, the combination of metformin with other glucose-lowering drugs does not result in significant weight gain and may also reduce the possible adverse effects of these drugs on body weight. These hypoglycemic drugs include insulin secretagogues, thiazolidinediones, and exogenous insulin. Metformin can improve the blood lipid status of diabetic patients to a certain extent, such as reducing the level of total cholesterol and triglycerides in the blood, and can increase the level of high-density lipoprotein HDL, which helps reduce the risk of cardiovascular disease complications in diabetic patients.

    3. Understand the advantages and disadvantages of metforminMetformin can increase local blood** and nutrient exchange, helping to reduce peripheral vascular resistance. It also contributes to a slight drop in blood pressure. It was reported that 254 patients with type 2 diabetes experienced a reduction in systolic and diastolic blood pressure of 11 3 and 13 3, respectively, after receiving metformin** for 6 months.

    Finally, is metformin the most hypoglycemic drug mentioned above? There are other medicines, and I will analyze it here today.

  2. Anonymous users2024-02-07

    Is metformin the "best" hypoglycemic drug? Are there any other medicines?

  3. Anonymous users2024-02-06

    Metformin is a good hypoglycemic drug, and there are also hypoglycemic drugs, including Baitangping, Damekang, Beixin, etc.

  4. Anonymous users2024-02-05

    Metformin is indeed a better hypoglycemic drug, of course, glimepiride and Fledi. These two medicines also have a certain effect, but it is best to ask your attending doctor according to your condition, and the doctor will recommend what medicine to take.

  5. Anonymous users2024-02-04

    There is no best hypoglycemic drug, I think each drug has its own symptoms, the right medicine is the best, like hypoglycemic drugs in addition to metformin and rosiglitazone, pioglitazone, repaglinide, sitagliptin, etc., each drug has its characteristics, and the effect of different drugs is not the same.

  6. Anonymous users2024-02-03

    Metformin is the "best" hypoglycemic drug, very cost-effective, it is a hypoglycemic drug that ordinary people can eat, and there are other hypoglycemic drugs, but it is generally very expensive, and it is not recommended to buy!

  7. Anonymous users2024-02-02

    What should I do if I take metformin and lose my hair, but it's amazing.

  8. Anonymous users2024-02-01

    For most patients, the hypoglycemic effect of this drug is very good. Moreover, the ** of this drug is relatively cheap, so in the process of taking the drug, it will not bring a greater financial burden to everyone. And the efficacy of this drug is very obvious, and at the same time it can play a role in lowering blood pressure.

    This medication is not suitable for patients with liver disease. <>

    Many middle-aged people will have elevated blood sugar, and once the blood sugar exceeds the standard, the health of the human body will be greatly affected. Therefore, in daily life, many patients will choose to take some hypoglycemic drugs to control their blood sugar standards. You will find that there are a variety of different hypoglycemic drugs on the market, and the standards of various drugs are different.

    In this process, many people will choose hibiscus, a hypoglycemic drug, because its efficacy is very good. And in the process of taking the drug, you will find that the ** of the drug is also very cheap. Therefore, in the process of buying medicine, everyone will not have too much pressure.

    And this drug is very safe, and at the same time has some other effects. For patients with high blood pressure, everyone can also choose to take this medication. Because middle-aged people have particularly low immunity, they are susceptible to a variety of different diseases.

    For obese patients, there is also an option to take this medication. There is also a patient who has symptoms of hyperlipidemia, and in this process, everyone can also choose to take the drug. Because the drug can reduce the body's blood lipid levels without affecting the body's health.

    But in the process of taking the drug, you must read the instructions for use. Because the drug is not suitable for all people, in the process, you will find that some patients have liver disease or kidney disease. For these patients, they are not suitable for taking this medication because it may also cause damage to the kidneys during the course of taking the drug.

    There are also some patients whose gastrointestinal system is not particularly good and may experience diarrhea during the process of taking the drug. Therefore, this kind of people are not suitable for taking the drug.

  9. Anonymous users2024-01-31

    Metformin is indeed a more conventional drug, which can indeed maintain the stability of blood sugar, but for many diseases, it is indeed not the best drug, because some people use it, but it is still not suitable for some people; For example, some diabetic patients who have liver and kidney function are impaired, but they are actually not suitable for taking metformin.

  10. Anonymous users2024-01-30

    This is indeed a better hypoglycemic drug; People who are allergic to this drug, people with unsound kidney function, lactating women, patients with alcoholism, children under 10 years of age, these people are not suitable for the use of this drug.

  11. Anonymous users2024-01-29

    I think that's better for that; Patients with severe renal insufficiency, patients receiving intravascular injections of iodinated contrast, patients with vitamin B12 and folic acid not corrected, children under 10 years of age, lactating women.

  12. Anonymous users2024-01-28

    No, if you are too fat or very thin, you have heart disease or respiratory diseases and vascular diseases, it is not suitable.

  13. Anonymous users2024-01-27

    Shandong: "Qi Ji", easy to use. Beijing Shuanghe production: "Bu Ke", easy to use.

  14. Anonymous users2024-01-26

    It seems that in addition to ordinary metformin (there are more of these types), there are also metformin ordinary sustained-release tablets (there are also more of them), and there is an upgraded version of metformin ordinary sustained-release tablets Metformin sustained-release tablets, ** and related effects seem to be gradually increasing! Metformin sustained-release tablets ( ) are currently only available in Dulening (a national high-tech enterprise produced by Chongqing Conkel, specializing in the development and production of chronic diseases such as diabetes), which is smaller in size, lighter in weight, more stable in blood sugar control, and smaller in the stomach!

  15. Anonymous users2024-01-25

    With Dulenin (metformin extended-release tablets II), the blood sugar was controlled smoothly, and there were no gastrointestinal adverse reactions as they said. I heard that the reason why it is called II is because it uses a new type of controlled-release technology, which can ensure that blood sugar will not be on a roller coaster. If you have been using 20 grams, you will be reimbursed by Class B medical insurance for a few dollars.

  16. Anonymous users2024-01-24

    Imported ones are not necessarily better than domestic ones, the same is true, Gehua Zhi pills are so big, and the domestic Du Lening is only about half the size, if you take 4 capsules a day as required, Gehua Zhi is so big. And Du Lening is still a controlled-release tablet.

  17. Anonymous users2024-01-23

    Let's start with what I ate myself: imported Gehuazhi. 500mg *20 tablets per box, hospital-prescribed, per box.

    Because it can be reimbursed by full medical insurance, it is not very sensitive to **, so it is imported. I have also opened a domestic one before: Medicon.

    I'm not a very delicate person, so I didn't notice a big difference. However, I heard that some diabetic patients are not well controlled with domestic metformin, and they switch to imported Gehuazhi, and their blood sugar is cured. At first, I had an extremely nauseous feeling when I took metformin, but then it was gone.

    View the original post

  18. Anonymous users2024-01-22

    I used to take Metformin Hydrochloride enteric-coated tablets, 48 tablets per bottle, about 12 yuan. Due to the frequent forgetting to take the medicine: $ after changing to Yuedanin hydrochloride metformin hydrochloride extended-release tablets. Personally, I feel that I can also view the original post

  19. Anonymous users2024-01-21

    According to the 2nd floor, it is better to change to imported ones if the control of domestic products is not good, is it better to import them with higher purity and better results? I now use domestic sustained-release capsules (Producer: Shenyang Aohua Pharmaceutical****, brand:

    Angel, trade name: Bai Siping) The control effect is still ideal, is it necessary to change to Gehuazhi? Will the imported ones be smaller?

    View the original post

  20. Anonymous users2024-01-20

    Metformin with exercise,**Not bad,I now have a body mass index View the original post

  21. Anonymous users2024-01-19

    Beijing Shuanghe's metformin hydrochloride tablets, grams, 30 tablets, it seems to be more than 2 yuan, and the community hospital prescribes it. View the original post

  22. Anonymous users2024-01-18

    My grandmother has been diabetic for several years on the second floor, what was the name of Gehuazhi used before, the effect was not very good, mainly diarrhea, and now I have been using Durene metformin, I feel that the effect of this medicine is not bad, not so diarrhea.

  23. Anonymous users2024-01-17

    Most of the metformin effects on the market are the same, metformin is mainly to lower blood sugar, if you want metformin to play to the extreme, you must match seaweed chromium. Metformin can enhance your sensitivity to insulin and speed up blood sugar utilization. If it is combined with chromium algae, the chromium provided by the algae doubles to enhance the insulin effect, and encapsulate sugar and fat in the small intestine to delay their absorption.

    The two work together to reduce blood sugar smoothly and reduce the occurrence of complications. At the same time, it can improve insulin utilization, delay the absorption of sugar and fat, reduce blood sugar smoothly, and reduce the occurrence of complications. (Effective for stage I and II diabetes mellitus and pre- and postprandial hyperglycemia).

  24. Anonymous users2024-01-16

    Medicon, ** is not expensive, we have it in most pharmacies here.

  25. Anonymous users2024-01-15

    I had diabetes four years ago and I took regular metformin tablets and it didn't work very well. Now I have been taking Yuedaning, and I feel that the effect of this medicine is not bad.

  26. Anonymous users2024-01-14

    For any disease, there is no best drug, only the "best" drug that meets and adapts to the patient's own condition, and patients need to choose the drug that is more suitable for their disease and their own situation. Metformin has a wide range of applications, can be used by diabetics of almost all ages, and is especially suitable for obese diabetic patients, so far metformin is the first choice of first-line drugs for type 2 diabetes.

    Metformin is a conventional drug for type 2 diabetes, which can improve glucose utilization and insulin sensitivity. In most diabetes medication guidelines such as the guidelines of the Diabetes Society in China, metformin is used as a first-line drug for diabetes.

    Metformin reduces the rate and total amount of glucose absorbed by the intestines, inhibits the breakdown of glycogen, and reduces the input of glycogen into the liver, thereby reducing the total amount of glucose entering the bloodstream. Metformin can also increase the sensitivity of surrounding tissues to insulin, making insulin active and playing a role in lowering blood sugar.

    Metformin also activates the enzyme AMPK, which is responsible for controlling the amount of glucose converted into blood sugar, which causes the body to consume more glucose, thereby lowering blood sugar levels.

    Another effect is that metformin will accumulate in the intestinal area after washing hands, allowing the intestinal tissue to quickly digest a large amount of glucose into lactic acid, reducing the peak blood sugar after meals. This lactic acid will enter the liver with the blood, and when the blood sugar drops, it will re-enter the liver, and be processed by the liver to become glucose, which can be used by the body to maintain the stability of blood sugar. That is, there is no hypoglycemia.

    1. It is suitable for patients with type 2 diabetes, especially those with obesity and overweight type 2 diabetes.

    2. It is suitable for patients who use a certain oral hypoglycemic drug alone or insulin alone, and the effect of blood sugar control is not good, or it is ineffective, and the combination of metformin can be considered.

    3. Patients with impaired glucose tolerance can choose metformin.

    Although metformin is the first-line hypoglycemic drug for type 2 diabetes, it is not suitable for all patients with type 2 diabetes. The following groups of people are not suitable.

    1. Patients with moderate renal insufficiency: when renal function is impaired and the glomerular filtration rate is lower than 45, the drug needs to be stopped. Because metformin is prone to accumulation and poisoning.

    2. People who are allergic to metformin are prohibited: some people are allergic to metformin, and these people are not able to use metformin drugs.

    4. Patients with special diseases cannot be used: the use of metformin in the case state will lead to life-threatening occurrence due to metabolic disorders, so metformin cannot be used for some serious special diseases, such as severe trauma, major surgery, acute and chronic metabolic acidosis, diabetic ketoacidosis, and those receiving intravascular iodinated contrast agents need to stop taking metformin drugs.

    In addition, metformin should not be used in a drunken state, or in a state of severe vitamin B12 deficiency.

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Who said that metformin hurts the kidneys??? I have been practicing medicine for 20 years, and I first started to use metformin for patients in 1995, when the beta melon had not been withdrawn from the market, and I had repeatedly checked the information and did not say that it hurt the kidneys, at that time, a box of 48 tablets of metformin was 56 yuan. It is much more expensive than now, and with the increase in the number of diabetic patients and the increase in patients taking metformin, I don't know when it was said that metformin hurts the kidneys. >>>More

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Most of the oral hypoglycemic drugs such as metformin, glipizide, and glibenclamide, which are commonly used in diabetes, will cause some damage to the liver, so the medication regimen for diabetic patients will increase liver protection**. That is, while taking hypoglycemic drugs, add hepatoprotective drugs such as liver protection tablets to prevent the damage of hypoglycemic drugs to the liver, and also have a certain synergistic effect on diabetes, because diabetes itself will induce fatty liver and worsen liver function.

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