What are the early symptoms of motor neurone disease?

There are three clinical types of MND, the early symptoms of MND vary depending on the type, the lower MND usually begins with small muscle weakness and gradual muscle atrophy in the hand, which can affect one side, both sides, or start on one side and then spread to the opposite side. The upper motor neuron type is characterized by limb weakness, tightness, and ineffective movements, and the upper and lower motor element mixed type usually has hand muscle weakness and muscle atrophy as the first symptoms, which generally starts from one side and then spreads to the opposite side, and the symptoms of mixed damage of upper and lower motor elements appear with the development of the disease, which is called amyotrophic lateral sclerosis.

Motor neuron disease usually has an insidious onset and a slow progression. Due to the different locations of injury, the clinical manifestations are different combinations of symptoms such as muscle weakness, muscle atrophy, and bulbar paralysis. In many cases, one type of presentation is present, followed by another, and finally ALS.

As a result, it can sometimes be difficult to determine which type it belongs to in the early stages of the disease.

1. Typical symptoms.

1. Amyotrophic lateral sclerosis: The common first symptom is clumsiness and weakness of one or both fingers, followed by atrophy of small finger muscles, which gradually develops to the muscles of the forearm, upper arm and shoulder. As the disease progresses, muscle weakness and atrophy extend to the trunk and neck, and eventually to the facial and laryngeal muscles.

In a few cases, muscle atrophy and weakness begin in the lower extremities or trunk. Fasciculations are often evident in the affected area.

2. Progressive muscular atrophy: The common first symptom is atrophy and weakness of the small muscles of one hand or Yu Hanchun's hands, which gradually affects the muscles of the forearm, upper arm and shoulder. Affected muscles are markedly atrophied, muscle tone is reduced, and muscle tremors may be seen.

3. Progressive bulbar palsy: the main elder complains that it is manifested as progressive slurred articulation, difficulty in swallowing and intolerance, choking on drinking water, and weakness in chewing. The tongue muscles are obviously atrophied, and there are fasciculations, and the lip muscles and throat muscles are atrophied.

This type of disease progresses rapidly, and most of them die within 1 to 2 years due to respiratory muscle paralysis or lung infection.

4. Primary lateral sclerosis: the common first symptom is symmetrical stiffness and fatigue of both lower limbs, and walking with a scissor gait. Progresses slowly and gradually affects both upper extremities. There is usually no muscle atrophy and fasciculations, and no sensory deficits. This type progresses slowly and can survive for a long time.

2. Other symptoms.

A small percentage of patients with motor neuron disease have manifestations outside the motor system, such as dementia, paresthesia, and urinary and urinary dysfunction, and a small number of patients have extraocular muscle movement disorders.

MND can manifest as weakness and atrophy of the limbs, clumsiness and weakness of finger movements, muscle weakness and atrophy over the course of the disease, extending to the trunk and neck, and finally involving the facial and throat muscles. Patients may have bulbar paralysis, mostly in the late stage, the tongue muscles are first involved, manifested as tongue muscle atrophy, fasciculation and tongue protrusion weakness, followed by pharyngeal, laryngeal, and masticatory muscle atrophy and weakness, so that the patient has unclear articulation, difficulty in swallowing, difficulty in chewing, and orbicularis oculi muscle involvement is more obvious in the facial muscle. There is often a pattern of disease progression in MND, usually from the upper extremity that is first affected, then to the contralateral upper extremity, to the ipsilateral lower extremity, to the contralateral lower extremity, and finally to the bulb involvement.

Motor neuron disease can be life-threatening, mostly within 3 to 5 years, death from respiratory muscle paralysis or lung infection, so motor neuron disease is more harmful. You can come to Beijing Renxuan Traditional Chinese Medicine to find Sheng Jinqiangfu**, Cong Mo can improve the patient's symptoms through one-to-one conditioning of Yiyuan Muscle Formula.

Motor neuron disease begins with symptoms in the hands, followed by progressive muscle atrophy in the distal limbs, and more than half of the patients have muscle atrophy in the early hand-sized thenar, and then extends to the forearm muscles, pectoralis major muscles, back muscles, etc. Causes hypertonia, difficulty moving, breathing and swallowing disorders, and fasciculations. The following are typical symptoms of motor neurons.

1. The first symptom of motor neuron is on the hand, and the patient will feel stiff and clumsy fingers, weak movements, gradual atrophy of hand muscles and fasciculations.

2. It can also lead to tongue muscle atrophy with tremor, resulting in slurred speech, difficulty swallowing and chewing weakness, and later will lead to systemic muscle atrophy, bedridden, respiratory insufficiency, belonging to the type of lower motor neurons.

3. Motor neurons can cause limb weakness, muscle tension and difficulty walking, this phenomenon belongs to the type of upper motor neurons, most patients develop the disease after adulthood, and the progress is usually slow.

MIN TCM belongs to the category of dysentery, and the soup of MIN Jin Quan Yuan can be used as a reference.

The most prominent state in the early stage of motor neuron disease is fatigue, which produces weakness of the limbs, chest tightness, and breath holding. At the same time, motor neuron disease can produce fasciculations of the muscles innervated by the diseased nerves in the early stage, and some of them can occur in the early stage of loss or loss of tendon reflexes.

1. Early symptoms.

There are many early symptoms of motor neuron disease, such as muscle weakness, inconvenience in moving, and choking when eating and drinking. If you have phlegm, you won't be able to cough it up. In the later stages, speech is slurred and muscles are atrophied extensively.

Motor neuron disease is a disease of the nervous system, and its early symptoms are many, such as unilateral or bilateral hand muscle weakness, atrophy of thenar muscles, difficulty in moving, difficulty breathing, and choking even when eating and drinking. And the phlegm can't be coughed up. In the later stage of development, the muscles of the upper brother's limbs and scapula muscles will atrophy, and he will not be able to swallow normally.

2. Motor neuron disease**.

When muscle atrophy occurs, it is necessary to use drugs that regulate and nourish the nerves**, and if necessary, hospitalization**. During the ** period, patients need to drink more water, eat more foods containing vitamins, and eat high-protein foods appropriately, and pay attention to exercise. When exercising, choose the right way according to your own situation.

Typical symptoms: upper and lower motor nervous system involvement is the main manifestation.

Common symptoms: muscle weakness, muscle atrophy, and fasciculations and tremor are manifestations of lower motor nervous system involvement; Hypertonia, hyperreflexia, and positive pathological signs are the main manifestations of upper motor nervous system involvement.

Other symptoms: the first symptom of reverence can be a variety of manifestations depending on the patient. Most patients have asymmetrical local limb weakness, such as stiffness when walking, procrastination, easy falling, and inflexible finger movement.

Bulbar symptoms such as dysphagia and dysarthria. A small number of patients present with respiratory symptoms.

Motor neuron disease (MND) is a disease that has a relatively slow onset and a more insidious onset.

Early symptoms are muscle weakness, inability to lift things, and muscle atrophy.

Sometimes, due to muscle atrophy, the hand is like an eagle's claw, and it gradually extends to other muscle groups, and the symptoms become more severe.

Muscle throbbing and trembling, weakness in chewing and even difficulty breathing are the early symptoms of MND.

The early symptoms of MND include fatigue and weakness, exercise intolerance, sleep disturbance, emotional instability, and even poor swallowing of food and drink.

There are many types of motor neuron disease, which can be roughly divided into two aspects:

Clause. 1. Upper motor neuron disease;

Clause. 2. Lower motor neuron disease.

Symptoms caused by upper motor neuron disease are affective disorders, such as forced crying, forced laughter, increased muscle tone, pyramidal tract signs, or muscle spasms; Lower motor neuron disease directly causes muscle atrophy and decreased muscle strength, such as weakness and muscle atrophy of the limbs.

The early symptoms of MND are relatively mild, and there are no obvious typical symptoms, such as fatigue and weakness, exercise intolerance, sleep disorders, emotional instability, emotional disorders, and even eating and drinking that is not smooth, or muscle cramps and frequent muscle beating, etc., are all early symptoms.