What is the effect of taking Tongxinluo for acute myocardial infarction?

Tongxinluo is a more commonly used Chinese patent medicine, widely used in cardiology and neurology diseases, the current clinical evidence is also relatively sufficient, the main function is for the prevention of coronary heart disease, angina pectoris, can reduce the frequency and time of angina pectoris, and can also be used for stroke caused by qi and blood stasis, such as stroke. This drug can be clearly seen in Western medicine, mainly to reduce the degree of myocardial ischemia in the acute myocardial infarction model, reduce the scope of myocardial ischemia, improve myocardial oxygen supply, and can also increase the flow of coronary blood. The use of drugs after myocardial infarction can also inhibit ventricular remodeling and improve the long-term prognosis of the heart.

At the same time, some stroke patients can reduce the scope of ischemia, reduce the permeability of cerebral blood vessels, and reduce cerebral edema after the application of this drug.

The clinical study led by Professor Yang Yuejin of Beijing Fuwai Hospital showed that the addition of Tongxinluo Capsule on the basis of conventional ** before and after surgery can significantly improve myocardial blood perfusion, reduce the area of myocardial infarction, and improve cardiac function. Combined with a number of previous research evidence and clinical experience, Professor Yang Yuejin's research group proposed a "heart triple"** scheme of combined application of Tongxinluo capsule, load statin and nicorandil. This program can protect the structure and functional integrity of myocardial microvessels, prevent myocardial reflow and myocardial hemorrhage after acute myocardial infarction, reduce the area of myocardial infarction, and improve the prognosis of patients.

Hello, Tongxinluo is a Chinese patent medicine that regulates the heart and cerebrovascular, aspirin is an anti-platelet aggregation drug, atorvastatin is a hypolipidemic drug, the above three drugs are not thrombolytic drugs, and acute myocardial infarction is now generally done to do access quality effect, these can be taken after myocardial infarction intervention, of which aspirin is taken for a long time.

According to statistics, about 37% of patients with acute myocardial infarction do not have effective blood perfusion restored after stent placement**. This is due to the fact that when a myocardial infarction occurs, after the large blood vessels are blocked, the microvessels connected to it are unable to transport blood to the myocardial cells due to ischemia and hypoxia necrosis, and this phenomenon is called myocardial reflow after myocardial infarction intervention.

Tongxinluo capsule has a microvascular protective effect, which can reduce the myocardial reflow after stent placement in myocardial infarction. Professor Yang Yuejin of Fuwai Hospital of the Chinese Academy of Medical Sciences added Tongxinluo Capsule on the basis of myocardial infarction routine** to improve myocardial blood perfusion (24-hour electrocardiogram ST segment complete regression rate increased by 20%), reduce the area of myocardial infarction, and improve cardiac function.

In addition to being conducive to dredging large blood vessels, Tongxinluo Capsule can also protect microvessels and improve microcirculation. Heart attack.

After intervention, "myocardial reflow", "reperfusion injury" and cerebral infarction.

The sequelae are caused by microvascular damage and the inability of blood to be effectively transported to ischemic tissues.

In addition to regulating blood lipids, protecting the endothelium, anti-inflammatory and anticoagulant, stabilizing plaques, inhibiting vasospasm and other dredging large blood vessels, Tongxinluo Capsule can also protect microvessels, promote microangiogenesis, improve microcirculation, and thus improve blood perfusion in ischemic areas. Reduce the incidence of "no reflow of myocardium after reperfusion" and "reperfusion injury", and improve hemiplegia caused by cerebral infarction.

Symptoms such as poor speech, numbness of the limbs, and depressed mood.

There are still dense microvessels between our large blood vessels and various organs and tissues, and the blood in the large blood vessels can eventually reach the tissues and organs through the microvessels and play the role of nutrition. Tongxinluo capsule can prolong the survival time of microvascular endothelial cells in ischemia and hypoxia environment, improve the impact resistance of microvessels, so that they can maintain normal blood flow pathways after the dredging of large blood vessels, and provide nutrition to the heart, brain and other organs; Tongxinluo Capsule can promote the regeneration of microvessels in the ischemic area, open up new blood pathways for it, and thus improve the blood in the ischemic area**.

For example, for patients with cerebral infarction, the microvasculature is protected, a new collateral circulation is established, and the ischemic area of the brain can also be irrigated, and the patient's symptoms such as hemiplegia, poor speech, numbness of limbs, and depressed mood will gradually improve.

The choice of stents is risky, but the effect is good, and the effect is average but the risk is small. So choose according to your actual situation.

Drugs. Coronary artery dilation medications.

For example, nitroglycerin is suitable for the vast majority of patients with acute myocardial infarction, and patients with obvious hypotension should use it with caution.

Drugs that reduce myocardial oxygen consumption.

For example, metoprolol, bisoprolol, etc., should be used with caution in patients with low blood pressure and slow heart rate, and patients with acute cardiac insufficiency should also be used with caution.

Antithrombotic drugs.

Including antiplatelet drugs, anticoagulants, such as aspirin, clopidogrel or ticagrelor, heparin, etc., can inhibit the formation of thrombosis that blocks blood vessels or further increases the size of thrombosis.

Lipid-modifying drugs. It mainly refers to statins, including atorvastatin, rosuvastatin, pravastatin, simvastatin, pitavastatin, fluvastatin, etc., and cholesterol absorption inhibitors can be added if the blood lipid does not meet the standard.

High-risk patients with significantly elevated blood lipids can also use PCSK9 inhibitors, which can delay the progression of coronary atherosclerosis in the long term and avoid the recurrence of acute myocardial infarction.

Thrombolytic drugs. Thrombus lysis of embolic vessels should be used under close hospital supervision.

Percutaneous coronary intervention**.

Indicated for patients with clear ECG signs within 12 hours of symptom onset. It needs to be performed by an experienced physician in a hospital with a cardiac catheterization laboratory**. Balloon plasty, stent implantation, etc., which are performed after intervention according to the obstruction, although the overall cost is high, compared with thrombolysis, intervention.

has a higher rate of vascular opening, a wider range of indications, and fewer bleeding complications, so it is more recommended to prioritize interventional implementation in patients with acute myocardial infarction**.

Emergency coronary artery bypass grafting.

For patients who have failed interventions** or who have failed thrombolysis**, or who have mechanical complications requiring surgical correction. The surgical procedure is complex and invasive, and the corresponding surgery-related risks are also greater.

Myocardial infarction is acute myocardial infarction, and it is better to put a drug balloon or a stent to make a comprehensive judgment based on the development of the patient's own condition, and cannot be generalized.

1. Drug balloons:

Clinically, it is mainly used for patients with infarction and stenosis of small blood vessels, and it is better to use drug balloons for patients who have a history of stents but have stenosis in the stent. During the procedure, the doctor needs to deliver a drug balloon through a guidewire to the narrowed blood vessel in the patient's body. Then it is quickly inflated to make the balloon dilate to open the narrowed blood vessel, and then deflate to remove the balloon, so as to achieve the purpose of dilating the blood vessel.

2. Stent: a common way of acute myocardial infarction in clinical practice, patients with acute myocardial infarction usually need to improve infarction and vascular stenosis in a short period of time, and stent placement can quickly alleviate the patient's symptoms and effectively prolong the patient's survival. Therefore, for patients with myocardial infarction within 6 hours, it is better to choose a stent**.

Balloons and stents are common clinical methods of acute myocardial infarction, and there are advantages and disadvantages between the two, and doctors will choose the most suitable method according to the actual condition of the patient. It is recommended to follow the doctor's instructions**.

Which is better, myocardial infarction stent or conservative medication, the original intention needs to be decided according to the severity of the patient's condition. If the disease is mild, conservative** is usually used; However, if the condition is more severe and critical, it is necessary to undergo myocardial infarction stent surgery in time**. However, stent surgery is not a panacea, and blood vessels in other parts of the heart, or where the stent is placed, may be reblocked, resulting in a myocardial infarction**.

So, even if you have a stent, you still have to take medication**. Tongxinluo capsule is a commonly used drug for the prevention and treatment of myocardial infarction in clinical practice, which can protect the vascular endothelium, regulate blood lipids, anticoagulation, prevent plaque formation, and stabilize the plaque that has formed. In addition, it should be combined with the use of drugs such as statins and aspirin, which are commonly used in clinical practice.