Will my body become resistant to antihypertensive drugs if I take them for a long time?

Drug resistance refers to the process by which a drug becomes less effective during use, or gradually becomes less effective. Antihypertensive drugs are not currently tolerated.

The body generally does not produce drug resistance, unless you still eat and drink after taking antihypertensive drugs and see obvious effects, and do not pay attention to your diet and work and rest habits, which will lead to the gradual increase of factors that cause high blood pressure, so that the antihypertensive drugs lose their effect, and you have to change to another antihypertensive drug.

Long-term use of the same antihypertensive drug will not produce resistance, and the antihypertensive effect will not be affected, on the contrary, taking the same antihypertensive drug, the adverse reactions of the drug will be weakened at the beginning.

If one antihypertensive drug is taken for a long time, the body does develop resistance. Therefore, patients with high blood pressure must change it appropriately for a period of time when they choose to take antihypertensive drugs.

Some patients with high blood pressure will be a little suspicious when taking drugs, and will think that long-term use of a blood pressure drug will develop drug resistance, and the drug will not have the effect it should have in the process of taking the medicine. In fact, this kind of thinking is wrong, when taking antihypertensive drugs, drug resistance will not be generated, as long as the antihypertensive drugs prescribed by the doctor are obtained, the blood pressure of patients with hypertension will be effectively controlled. Drug resistance mainly refers to the reduction of the efficacy of the drug to the human body, simply put, the effect of the drug will be weakened, and the acquired drug tolerance mainly refers to the reduction of the body's response to the drug after taking the drug for a long time.

However, if the antihypertensive drugs taken by hypertensive patients for a long time have a good effect and no adverse reactions, they do not need to change the drugs.

What are the possible benefits of taking blood pressure medication for a long time?

The advantage of taking antihypertensive drugs is that it brings stable control of blood pressure, which does not cause drugs and complications, and will also cause too much harm to the patient's life. Therefore, for patients, when taking drugs, they must strictly follow the doctor's instructions to take drugs, do not choose the type of antihypertensive drugs without authorization, and take them on time, and do not stop taking drugs at will. At the same time, you should monitor your blood pressure at home, understand your physical condition, and seek medical attention in time if there is any abnormality.

At the same time, it is necessary to do a good job in life intervention, focusing on light diet and appropriate exercise.

What kind of bad results can be produced by taking blood pressure medication for a long time.

Long-term use of antihypertensive drugs may cause some bad results, which is also more common in life, and may cause some drugs, such as bradycardia, headache, facial flushing, edema, dry cough, nausea, dizziness and vomiting, and some drugs may also cause liver and kidney damage. It may also cause some complications, such as coronary heart disease, myocardial infarction, arrhythmia, cerebral hemorrhage, cerebral infarction, etc.

Finally, there is no need for patients to worry, taking a drug for a long time will develop drug resistance, and some people do not have a good effect after taking the drug, which may be caused by the condition, so for this situation, it is necessary to adjust the antihypertensive regimen.

Long-term use of antihypertensive drugs does not produce drug resistance, as long as you take it according to your doctor's instructions, even if you take it for a long time, the effect will still be very good.

Long-term use of antihypertensive drugs will not develop drug resistance, as long as you take it according to the doctor's instructions, you do not have to worry even if you take it for a long time.

For example, patients with high blood pressure must take drugs to lower blood pressure every day, otherwise it is also likely to cause their blood pressure to rise rapidly, which poses a certain threat to life. However, taking blood pressure medication for a long time can also lead to some problems in the body, so I will talk about it carefully for you today.

One of the main reasons for high blood pressure is the heavy taste of the diet, and now many people do not eat heavy food, they feel that they can't eat, and if our diet is heavy, it will also lead to an increase in their blood pressure. There is also an irregular work and rest time, and many young people often like not to sleep at night and sleep during the day. Such a reversal of day and night habits will also lead to a series of problems in everyone's body.

If you take too many antihypertensive drugs, it may lead to the instability of uric acid, and many people with high blood pressure feel that taking more drugs can make their blood pressure more stable. However, if you take a large number of antihypertensive drugs, it will also cause our blood vessels to dilate, so that the acid concentration in the urine will rise, which will cause a series of symptoms such as gout. It will not only cause the instability of uric acid, but also cause damage to everyone's liver and kidneys, and antihypertensive drugs will cause some damage to our liver and kidneys.

Moreover, if you take it for a long time, a large number of antihypertensive drugs will also cause weakness in the limbs, which is because the potassium content in the human body is too low due to the regular urination of antihypertensive drugs, so if you need to take antihypertensive drugs, you can usually eat more foods containing potassium.

Antihypertensive drugs must be taken according to the doctor's guidance, and some patients with high blood pressure, if their usual blood pressure is relatively stable, they can actually skip taking antihypertensive drugs. Antihypertensive drugs are generally used to stabilize everyone's blood pressure when the blood pressure of hypertensive patients is very unstable, and if our blood pressure is stable enough, these drugs will only cause a certain burden on the body.

It can damage our liver, as well as organs in various parts of our body. Long-term use of antihypertensive drugs will also degrade our intelligence and make our body stiffer.

It can cause blood vessels to become more and more fragile, cough, cause bleeding, cause uric acid to rise, and cause kidney damage, all of which can cause problems.

It may cause the water in the body to decrease, resulting in an increase in uric acid, and it will also damage the kidneys and affect the blood vessels, and long-term use will form a kind of dependence.

Rumors

Antihypertensive drugs need to be changed regularly, and taking one medicine all the time can lead to drug resistance.

Debunking rumors

As a chronic non-communicable disease, hypertension has a high prevalence and disability rate, which has caused a heavy burden on families and society, and seriously consumed medical and social resources. Patients with high blood pressure should lower their blood pressure through lifestyle interventions and medications. Lifestyle interventions include the promotion of a healthy lifestyle and the elimination of behaviors and habits that are detrimental to physical and mental health, throughout the entire process.

On the basis of lifestyle modifications, antihypertensive drugs are selected and individualized according to blood pressure levels and cardiovascular risk**. Once hypertension is diagnosed, it needs to be adhered to for a long time**. Some patients who have been taking antihypertensive drugs for a period of time are worried about developing resistance and ask for a change in antihypertensive drugs.

So, can taking the same blood pressure medication all the time develop drug resistance?

In general, microorganisms, parasites, and tumor cells become resistant to drugs. Most commonly when antimicrobial drugs kill or inhibit bacteria, in order to strengthen their defense ability, various microorganisms resist the attack of antibacterial drugs by changing their own metabolic pathways or producing corresponding inactivated substances, so that the sensitivity of microorganisms to antimicrobial drugs is reduced or even disappeared. But hypertension is neither a microorganism, nor a parasite, nor a tumor, so it is not drug resistance.

Some patients take antihypertensive drugs, their blood pressure fluctuates, does not meet the standard, and the effect is not good, and they think that they have developed drug resistance. This is not the case, blood pressure is affected by many factors. A person's blood pressure fluctuates, is not static, and may be different every 1 hour in 24 hours.

In hypertensive patients, blood pressure is unstable, and other reasons need to be considered in addition to drug factors. For example, whether lifestyle adjustments have been made, whether salt intake has been reduced, whether appropriate exercise, regular work and rest and good mood are maintained every day, whether other risk factors such as dyslipidemia, high blood sugar, high uric acid, etc., and with age, the degree of arteriosclerosis increases, and many people's blood pressure will also change.

It can be seen that the patient's blood pressure is not well controlled after taking antihypertensive drugs, not because of drug resistance. If the oral drug has a good effect and there is no obvious ***, it can be taken for a long time and regularly, and there is no need to change or stop the antihypertensive drug on a regular basis. Regular drug changes may cause blood pressure fluctuations, which is not good for the condition and can easily lead to adverse events such as heart, brain, kidney and other organ damage.

Rumor refutation expert: Bian Yuan, deputy chief pharmacist of the Department of Pharmacy of Sichuan Provincial People's Hospital.

Review expert: Tong Rongsheng, director and chief pharmacist of the Department of Pharmacy of Sichuan Provincial People's Hospital.

Producer: Popular Science China - Science Refutes Rumors.

With the continuous advancement of the historical process, people's living standards and their economic level have been significantly improved, people's living conditions compared with the factors, now it has become a lot better, but although people have a variety of delicacies in their daily life, and will not worry about food problems, but now people's physique can be said to be relatively unhealthy, many people will have a variety of diseases, For example, a very common disease is high blood pressure Some middle-aged people also have high blood pressure, which is very common in our killing, and it is not easy to want this disease, and you need to take medication for a long time, and many people must have blood pressure medication at home in their daily life, butIf you drink blood pressure medication regularly, it will be very harmful to your body as follows.

1. Resistance In my opinion, if you take antihypertensive drugs for a long time, then your body will definitely develop resistance, and if your high blood pressure suddenly breaks out, when you take **, you will have resistance to many drugs, so I think this is one of the harms to your body when taking blood pressure drugs for a long time. <>

Second, it is very likely that edema will definitely have a variety of antihypertensive drugs for a long time, because everyone's physique is different and the situation is different, so some people will have edema in their lower limbs after taking antihypertensive drugs for a long time, and they also need to seek medical attention in time at this time. <>

3. According to the doctor's recommendation to buy antihypertensive drugs, many people think that there is only one antihypertensive drug, which is also specifically for lowering blood pressure, so some people will go to buy antihypertensive drugs alone, but there are many kinds of antihypertensive drugs, according to each person's situation, the doctor will recommend buying different antihypertensive drugs, so when buying antihypertensive drugs, you must follow the doctor's opinion. <>

The increase in blood pressure has a certain relationship with the liver and kidneys, but the first thing that is harmed by Western medicine to lower blood pressure is the liver and kidney, followed by the stomach and intestines! Most people who take blood pressure medication for a long time have no pulse!

The harm of taking antihypertensive drugs regularly is that if you take antihypertensive drugs regularly, it will produce a lot of toxins in the body, and these drugs will have high hormones, which may lead to high cholesterol, and will also cause some ***, which may cause edema and long-term dependence on antihypertensive drugs.

Often. Antihypertensive drugs will cause harm to the body, it may make the body dependent on antihypertensive drugs, and it may make your body produce antibodies to antihypertensive drugs, it will also cause the blood flow rate to become faster, and there will also be some liver damage, and it will also cause the metabolism of the kidneys to slow down, which are all harmful to the body by taking antihypertensive drugs regularly.

The harm is still relatively serious, for example, it will cause particularly serious damage to the liver and kidneys, and it will also affect the heart, and it will also affect the circulation of blood, and there will also be constipation or swollen and painful gums, and the body will also have edema.

Long-term use of antihypertensive drugs can cause damage to liver and kidney function, and in severe cases, it can cause cerebral hemorrhage, cerebral infarction, myocardial infarction, coronary heart disease, heart failure, and kidney failure.

Most patients with high blood pressure need to take antihypertensive drugs for a long time, but there will be some drugs more or less, and antihypertensive drugs have to be taken every day, which is very troublesome, so some people are reluctant to take medicine or take it when they want to, and they don't eat it if they can't think of it, but if the blood pressure rises for a long time, it will damage our heart, brain, kidneys and other important organs, causing serious complications such as stroke, angina, myocardial infarction, chronic renal failure, retinal arteriosclerosis, etc., so high blood pressure should be taken medicine. So how to reduce the *** of blood pressure medication? I summarized the following points for my friends:

Point 1: The dose of single drug increases, and adverse reactions are prone to occur, so antihypertensive drugs should be used at a small dose, and then the medication can be adjusted according to the blood pressure situation, some patients have high blood pressure, and the blood pressure cannot be lowered with a single antihypertensive drug, at this time, you can choose a combination of drugs or compound preparations under the guidance of a doctor: such as amlodipine, benazepril, valsartan, amlodipine, perindopril indapamide, irbesartan hydrochlorothiazide, etc.

Point 2: Don't change antihypertensive drugs at will or use whichever drug you want, each type of antihypertensive drug has its most suitable people and contraindications, such as reserpine can increase gastric acid secretion, and hypertensive patients with gastric ulcer or duodenal ulcer should not choose reserpine; Antihypertensive drugs are more suitable for hypertensive patients with hypertension combined with diabetes, coronary heart disease, and arteriosclerosis, because some hypertensive patients must choose antihypertensive drugs under the guidance of a doctor before taking medication.

Point 3: Choose a long-acting antihypertensive drug that only needs to be taken once a day, and then choose the appropriate time to take the drug according to the curve of blood pressure monitoring, for example, some patients have high blood pressure during the day, so they need to take the medicine after getting up in the morning. If your blood pressure is high during sleep at night, you need to take antihypertensive medication after dinner or before bedtime.

It is recommended to choose long-acting antihypertensive drugs that are taken only once a day, so that the blood pressure will be relatively stable 24 hours a day, and generally will not fluctuate too much, which will play a better role in protecting our heart, brain and kidneys and other important organs.

Point 4: In addition to taking medicine, we should put less salt when cooking, try to eat lightly, pay attention to rest, stay up less late, quit smoking and limit alcohol, and insist on moderate exercise. Check your blood pressure regularly and visit the hospital for regular follow-up.