What is rheumatoid arthritis, and will having rheumatoid arthritis drag down my family?

Rheumatoid arthritis is a very serious joint disease, and if this disease is particularly serious, it will completely drag down the family, because the mobility is limited and needs to be taken care of by the family.

Having rheumatoid arthritis will definitely not drag down your family, as long as you are good and your body recovers well, then you can live like a normal person, and you don't have to worry too much about work.

It will drag down the family, because they have this disease and need someone to take care of it, so the family can't go out to work or be busy with some other things

Our antibodies mistakenly attack normal synovial fluid and cause chronic inflammation. It can trigger symptoms of rheumatoid arthritis. In fact, it is the result of a very common autoimmune disease, and rheumatoid arthritis is more likely to affect women than men.

Rheumatoid arthritis is an autoimmune disease that requires long-term medication to control once diagnosed. Rheumatoid arthritis is not an autoimmune disease, and does not require long-term medication, mainly symptomatic**, keep warm, rest, and use some oral drugs.

Usually the joints on both sides of the body are equally affected, starting with the small joints of the wrists, hands, ankles and feet. Although this condition is not usually called a fatal disease, patients are twice as likely to die as people of the same age in the general population. Multi-systemic inflammatory autoimmune disease with systemic progressive joint damage and chronic systemic connective tissue disease.

It is characterized by symmetrical synovial inflammation of most joints, starting from the small joints and then invading the serous membrane, heart, lungs, eyes and other parts.

At present, there are many studies on the role of antigens, various inflammatory mediators, cytokines, and chemokines in the pathogenesis of rheumatoid, but none of them can fundamentally explain the pathogenesis and causes. Infectious factors include microorganisms such as Epstein-Barr virus, retrovirus, Mycobacterium tuberculosis, and Proteus mirabilis. Other factors include sex hormones, glucocorticoids, food, stress response, etc., which may have some influence on the development of the disease.

As for autoantibodies, our own immune system has a problem, and we mistake our own tissue cells for bacteria and viruses, and produce autoantibodies, which attack our own tissues, which leads to the onset of rheumatoid arthritis. Smoking induces the expression of an enzyme in alveolar macrophages, which then converts arginine to citrulline in the airways, causing the body to produce "anti-citrullinated protein antibodies" that can initiate an inflammatory response through complement in tissues.

Rheumatoid arthritis is an autoimmune disease that tends to occur in middle-aged and elderly women, and the main clinical characteristics of rheumatoid arthritis are bilateral symmetrical multi-joint swelling and pain, accompanied by morning stiffness, rheumatoid arthritis serological examination can show rapid erythrocyte sedimentation rate, increased C-reactive protein, positive rheumatoid factor, positive anti-CCP antibody, etc. Some people ask what is the ** of rheumatoid arthritis, and the onset of rheumatoid arthritis is not clear at present**, but it is related to many related factors, such as rheumatoid arthritis is more common in women, and many studies believe that there is a certain correlation with estrogen levels. Certain dysbiosis is also one of the causes of rheumatoid leakage arthritis, and it has been found that intestinal dysbiosis, periodontal infection, and airway microbiota are associated with the onset of rheumatoid arthritis.

Certain environmental factors are also associated with the onset of rheumatoid arthritis, such as cold and damp environments and exposure to chemicals such as silicon. Genetic factors are one of the main causes of the development of rheumatoid arthritis, and several genes have been identified to be associated with the pathogenesis of rheumatoid arthritis.

In the middle of clinical work, patients with rheumatoid arthritis often ask me with questions"Why do I have rheumatoid arthritis when others don't? "First of all, we need to know that the onset of rheumatoid arthritis may be related to genetics, infections, and sex hormones.

Microorganisms may be involved in the pathogenesis of rheumatoid disease, sometimes infected with microorganisms such as Epstein-Barr virus, parvovirus, mycoplasma, Proteus, oral and intestinal flora;

Heredity also plays a very important role in the onset of rheumatoid arthritis. Epidemiological studies have shown that the incidence of rheumatoid arthritis is closely related to genetic factors. In pedigree surveys, rheumatoid arthritis is found to be more than 11% more common in first-degree relatives with rheumatoid arthritis, and a large number of studies have shown that certain alleles are also associated with the development of rheumatoid arthritis.

Some sex hormones are also associated with the onset of rheumatoid arthritis, and you can find that some women have a significantly higher incidence of rheumatoid arthritis during menopause than men in the same year. This suggests that sex hormones are involved in the pathogenesis and development of some rheumatoid arthritis. In addition to sex hormones, other rheumatoid-related hormones, including prolactin, cortisol, etc.; And environmental factors also play a very important role in rheumatoid arthritis.

A cold, damp working or living environment can lead to the occurrence or aggravation of rheumatoid arthritis; In addition, smoking is also closely related to the onset and severity of rheumatoid arthritis. Rheumatoid arthritis can be caused by genetic factors, infectious factors, etc.

Genetic factors: According to surveys, the prevalence of rheumatoid arthritis in the general population is less than 1%.

However, the chance of developing rheumatoid arthritis is 4% for dizygotic twins and more than 12% for monozygotic twins.

Therefore, genetics is a big influence on rheumatoid arthritis.

People who have rheumatoid arthritis patients at home should pay more attention to their joints, observe more on weekdays, and seek medical attention as soon as possible if there is a problem.

Infectious factors: Epstein-Barr virus is a DNA virus that is mainly transmitted by saliva and can cause infectious mononucleosis, which is often referred to as "kissing disease".

Mycobacterium tuberculosis is an important factor in causing tuberculosis and enters the respiratory tract mainly through droplets or dust.

Humans are less resistant to Epstein-Barr virus and Mycobacterium tuberculosis, and most people have been infected with them.

Scientists have found that some tissue components of Epstein-Barr virus and Mycobacterium tuberculosis have similar structures to joint synovial tissue, which means they look more similar.

Therefore, scientists boldly speculate that the immune system mistakenly mistakes the synovium for Epstein-Barr virus and Mycobacterium tuberculosis to attack it.

If you want to protect your joints, it is best to stay away from Epstein-Barr virus and Mycobacterium tuberculosis so as not to disturb the immune system.

Immunity checking: If the blood test shows abnormal elevations of rheumatoid factor and anti-cyclic citrullinated polypeptide antibodies, it means that the immune system is abnormal, and there is a high possibility of rheumatoid arthritis.

Rheumatoid arthritis is a common rheumatic disease that occurs in middle-aged and elderly women, and its incidence is high, which can cause joint ankylosis and deformity, and make patients lose their ability to work, so it is more harmful.

Rheumatoid arthritis** and its pathogenesis are still unclear, but existing studies have shown that it is related to genetic, endocrine, sex hormones, and environmental factors.

Rheumatoid arthritis is easy to invade many joints in the human body, causing symmetrical swelling and pain, such as common hand joints, wrist joints, elbow joints, shoulder joints, knee joints, foot and ankle joints and toe joints, which are the most likely parts of rheumatoid arthritis to invade. Patients often feel that the joints are swollen, painful, and have limited flexion and extension, and the stiffness is more than 1 hour in the morning, which can be slightly relieved after activity.

People who are prone to rheumatoid arthritis are mainly people who have a family history of rheumatoid arthritis in their family or those who have genetic factors for connective tissue disease, women before and after menopause, people with endocrine dysfunction, and people who have been in a damp and cold environment for a long time.

are mainly people with weak constitutions, as well as people with a family history of rheumatoid arthritis or other connective tissue diseases, such as a close relative with systemic lupus erythematosus.

Sjögren's syndrome.

People with rheumatoid arthritis, etc. Rheumatoid arthritis is a multifactorial disease, a chronic and systemic autoimmune disease with erosive and symmetrical polyarthritis as the main clinical manifestation. The exact cause of the disease is unknown.

Rheumatoid arthritis is more common in middle-aged women and may be related to changes in estrogen. Moreover, the occurrence of the disease is also related to the long-term use of certain drugs, in addition, it is also related to long-term psychological pressure, mental overtension, overwork, etc., and may also be related to environmental factors, pathogenic microbial infection, etc.

There are six main groups of people with high incidence of rheumatoid arthritis.

1. Patients with rheumatoid arthritis in their blood relatives, such as parents, grandfathers, grandmothers, and siblings with rheumatoid arthritis, are more likely to develop rheumatoid arthritis.

2. Relatives with other rheumatic diseases, such as Sjogren's syndrome, systemic lupus erythematosus, scleroderma, etc.

3. Women are more likely to develop rheumatoid arthritis, especially menopausal women or perinatal women.

Fourth, long-term mental pressure is too great, in a tense and tired environment.

5. The place of residence or working environment is cold and damp, etc.

6. I have some kind of autoimmune disease, such as Sjögren's syndrome or systemic lupus erythematosus, and I am more likely to suffer from rheumatoid arthritis.

People who have a family history of rheumatoid arthritis or other autoimmune diseases, people who have been in cold and humid environments for a long time, the incidence of women is about 2-3 times that of men, and middle-aged and elderly people are prone to autoimmune diseases such as rheumatoid arthritis as they age.

Internal rheumatoid arthritis.

It is an unidentified chronic autoimmune disease with symmetric polyarthritis as the main manifestation.

People who are susceptible to rheumatoid arthritis mainly include people with genetic factors of connective tissue disease, or people with a family history of related medical conditions, as well as people who are susceptible to the invasion of various pathogenic microorganisms, people with poor physical fitness, people with endocrine dysfunction, and women before and after menopause, these groups are often prone to rheumatoid arthritis.

Of course, the factors that lead to the occurrence of rheumatoid arthritis are often a combination of factors, which will eventually lead to immune dysfunction and lesions due to a variety of reasons.

The following groups of people are susceptible to rheumatoid arthritis: 1. Rheumatoid arthritis.

People with a family history; 2. Women are more susceptible to rheumatoid than men; 3. People with long-term mental stress; 4. People who have been in a cold and humid environment for a long time are susceptible to infection with bacteria and viruses, invaded by wind, cold and dampness, and susceptible to rheumatoid arthritis; 5. Patients who already have some kind of autoimmune disease.

Someone in the family has rheumatoid arthritis, someone in the family has other rheumatic diseases, a menopausal or postpartum woman, a person who is chronically stressed or stressed, works or lives in an excessively humid environment, or has an autoimmune disorder.

Rheumatoid arthritis** is not fully understood, and the main related factors are: 1. Environmental factors, some infectious factors can affect the onset and progression of rheumatoid arthritis through certain pathways. 2 Genetic predisposition:

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to improve joint pain.

Because rheumatoid disease is a functional disease of the immune system.

Bone destruction occurs and is generally difficult to repair,** Purpose:

Clause. 1. Don't break the bones and protect the joints.

Clause. Second, what if it has happened, it is still necessary to standardize the long-term **, so that the destruction of the bone does not aggravate, so it must be long-term, generally speaking, it must be counted in years. At the beginning, you can keep some information, especially according to the ** of a hand, for example, after 2 years, 3 years, 5 years before and after a comparison will know how this ** effect, so no matter how you treat it, as long as the bone destruction is aggravated, your ** will definitely be unsuccessful.

What to do if you have rheumatoid arthritis, that is, those three, early standardization, long-term, persistence, so that you will get a relatively good effect and result.