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The main symptoms of muscle weakness are muscle fatigue and weakness, and in severe cases, muscle atrophy. The symptoms of muscle weakness fluctuate to a certain extent, most patients are mild in the morning and heavy in the afternoon, and the symptoms are significantly aggravated after labor or strenuous activities, and the symptoms can be relieved after rest. Some patients have ptosis, which may lead to respiratory failure and even life-threatening if the disease progresses.
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1. Weakness of limbs.
The most typical symptom of muscle weakness is weakness of the limbs and trunk, and it is often more severe in the lower extremities, and the lower extremities often have decreased or absent reflexes. In general, the muscle contraction after a short period of exertion leads to an increase in muscle strength, but the muscle strength will be greatly reduced after continuous contraction, so it presents a pathological fatigue response. In addition, patients may feel weak and weak throughout the day.
In severe cases, normal walking and activities may be affected.
2. Dry mouth.
Patients with muscle weakness may have symptoms of dry mouth, and even drinking water may not improve the response to thirst and dry mouth at all. The occurrence of this symptom may be related to abnormal autonomic function.
3. Dysphagia.
Although muscle weakness does not affect the digestive organs and does not affect the patient's appetite, symptoms of dysphagia may occur. People who want to eat but can't swallow it, and even have trouble drinking water, which may cause water to flow out of their nostrils due to choking. In severe cases, patients can only rely on nasogastric tubes to eat.
4. Respiratory tract infection.
It predisposes to the symptoms of respiratory tract infections, especially in infancy and childhood. At this time, many adverse reactions such as fever, hyperexcitement and vomiting can be manifested, and when the respiratory muscles become weak, it can lead to a great decrease in ventilation, which can lead to shortness of breath, even dyspnea, and hypoxic brain injury.
5. Facial numbness.
When the facial muscles become weak, patients are often unable to make expressions such as smiles, so there are always adverse reactions such as facial numbness and apathy. In addition, some patients may also have complications of subacute cerebellar degeneration and encephalomyelitis.
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Myasthenia is a neurology disease, which refers to the dysfunction of transmission at the neuromuscular junction caused by autoimmune causes, resulting in partial or systemic skeletal muscle weakness and easy fatigue, which will worsen after activity.
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Symptoms of muscle weakness, especially early symptoms, are often subtle or more likely to go unnoticed. Muscle weakness is a chronic condition. Many patients get tired easily, and rest can relieve the condition.
The early symptoms of muscle weakness are not obvious and are often overlooked. Patients with muscle weakness may have hoarseness and a heavy nasal voice in the early stages. The longer it passes, the more hoarse and low the voice becomes, and the sound doesn't come out completely.
This symptom is often thought of as a sore throat. Issue. While muscle weakness affects muscles throughout the body, the main area of impact is the eye muscles.
Patients may have symptoms such as diplopia and strabismus. Muscle weakness can also cause difficulty breathing, and many patients have symptoms such as difficulty swallowing, weakness in the limbs, or drooping eyelids. This manifestation is a more serious symptom that can kill a patient in a short period of time.
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Myasthenia is also called myasthenia gravis. Patients with myasthenia gravis have obvious fluctuations in symptoms, which worsen after work or walking, and can be relieved after rest, while the symptoms are milder in the morning and more severe in the afternoon. The main symptoms are:
First, there will be a pair of visions and drooping eyelids. In many patients, this may be the first symptom.
Second, the patient will have significant fatigue, especially after walking and climbing stairs.
Third, some patients will affect swallowing and have related clinical symptoms such as dysphagia, dysarthria, and choking on drinking water. In addition, there are some patients with severe conditions that will affect respiratory function, and they will have dyspnea and respiratory failure, which is more dangerous. Myasthenia gravis must be diagnosed as soon as possible, and the patient must be given medication as soon as possible to improve the symptoms.
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Ptosis: This is caused by paralysis of one or both extraocular muscles and may be accompanied by strabismus.
In double vision, in severe cases, eye movement is significantly limited, or even the eyeball is fixed, but the pupillary sphincter is not affected, that is, the pupillary accommodation function is normal;
Dysphagia and chewing: This is caused by the involvement of the facial and throat muscles, and at the same time, there will be an indifferent expression, a wry smile, continuous chewing weakness, choking on water, and more laborious swallowing of chewed food when eating;
Hoarseness: This is also caused by the involvement of the facial and throat muscles, which can be accompanied by nasal speech, dysphonia, and unclear pronunciation when speaking;
Difficulty raising head: when the sternocleidomastoid muscle and trapezius muscle are involved, it manifests as neck weakness, difficulty in raising the head, weakness in turning the head and shrugging the shoulders;
Weakness of the arms and legs: The muscles of the limbs are affected by proximal weakness, which is manifested as difficulty in raising the arms, combing the hair, and climbing stairs, but the tendon reflexes are usually unaffected and the sensation is normal;
Dyspnea: Respiratory muscle involvement often leads to adverse consequences, and medical attention should be sought as soon as possible if you experience difficulty breathing;
Morning and evening severity: this is a characteristic of the symptoms of the disease, i.e., daily fluctuations, muscle weakness that worsens after exertion in the afternoon or evening and lessens after morning or rest.
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