What is the dialectic of death in systemic lupus erythematosus

In recent years, immunology in medicine has developed rapidly, and on this basis, the concept of autoimmune diseases has been proposed, and the disease lupus erythematosus is considered to be a natural onset and unknown.

There are genetic factors, more common in women of childbearing age, lesions in multiple organs of the body, various clinical manifestations, a variety of high-titer autoantibodies can be detected in the blood, and there are relevant symptoms after the invasion of the corresponding body tissues (target organs), there are a large number of lymphocytes and plasma cell infiltration in the lesion tissues, and the use of corticosteroids and immunosuppressive drugs is effective, so lupus erythematosus should be classified as an autoimmune disease.

Not so long ago, lupus erythematosus was difficult, the prognosis of patients was poor, and the mortality rate was high. However, with the deeper understanding of it, especially after the application of new test methods and corticosteroids, the prognosis of lupus erythematosus has been greatly improved. In the last 10 years, the five-year survival rate has increased to more than 90%.

With the rapid development of medicine, it is believed that the prognosis of this intractable disease will be greatly improved.

Severe cases of systemic lupus erythematosus can be life-threatening, and the main causes of death include kidney failure, lupus encephalopathy, and secondary severe infections. Lupus erythematosus is a multi-organ, multi-system injury that causes death from the following:

Clause. 1. Kidney failure is one of the main causes of death from lupus erythematosus, and in severe cases, renal insufficiency and uremia can lead to death.

Clause. 2. Lupus encephalopathy, the manifestation of lupus encephalopathy is mainly the invasion of the nervous system by lesions, and patients can have seizures and acute encephalitis.

Clause. 3. Inflammatory infection, lupus erythematosus can lead to a decrease in the body's immunity, a decrease in white blood cells and platelets, and an inflammatory infection.

Clause. 4. Other causes, such as severe respiratory involvement, can lead to respiratory failure due to pulmonary fibrosis. Heart failure can be caused by the involvement of the cardiovascular system, which is a serious complication that causes death.

Severe clinical renal impairment, as well as respiratory failure, heart failure, and lupus encephalopathy are all signs of poor prognosis.

Answer] Suspicion: e

SLE** is unclear and may be associated with excessive fatigue; mental trauma; Heredity; sex hormones (mariastrens); Environment, such as sunlight, food (some foods containing psoralen, L-cancanavansyl, hydrazine groups, etc.), drugs (procainamide, isoniazid, chlorpromazine, methyldopa), chemical reagents and pathogenic microorganisms (Qinling socks virus and other infections), etc.

Answer]: B The pathogenesis of systemic oak lupus erythematosus is related to genetic factors, endocrine factors and environmental factors.

1.Genetic factors SLE is a polygenic disease, and genes are associated with clinical subtypes and autoantibodies.

2.Environmental factors mainly include ultraviolet rays, drugs, chemical wheel reagents, microbial pathogens, etc., which can induce the disease.

3.Endocrine estrogen levels are elevated, etc.

Answer]: The ** of ESLE is not clear, and it is currently believed to be related to extinction, sex hormones, environmental factors with finches (sun exposure), drugs (procainamide, chlorpromazine) and so on. The main triggers are excessive fatigue, trauma, sun exposure, and infection.

This question is aimed at the knowledge points of "basic knowledge - systemic lupus erythematosus** and pathogenesis, and auxiliary examinations".

Answer]: C Causes of systemic lupus erythematosus: (1) genetic factors (2) lead and environmental factors (3) hormones (4) immunocompromise. A high-protein diet is not a cause of systemic lupus erythematosus.

Answer]: Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease in the potato hall, due to the presence of a large number of pathogenic autoantibodies and immune complexes in the body, causing pure tissue damage, clinical symptoms of multiple systems and organ damage can occur, and most young women travel to hide.