What are the major improvements in the emamectin benzoate process?

1) Applicable crops: Emamectin benzoate is highly safe for all crops in protected areas or at 10 times the recommended dosage, and has been used in many food crops and cash crops in Western countries. Considering that it is a rare green pesticide.

China should first use it to control pests on cash crops such as tobacco, tea, cotton and all vegetable crops.

2) Mechanism of action: emamectin benzoate can enhance the action of neuroticism such as glutamate and monoaminobutyric acid (GABA), so that a large number of chloride ions enter nerve cells, so that cell function is lost, nerve conduction is disturbed, and the larvae stop eating immediately after contact, irreversible paralysis occurs, and the highest mortality rate is reached within 3-4 days. Because it is tightly bound to the soil, does not leach, and does not accumulate in the environment, it can be transferred through translaminar movement, and is easily absorbed by crops and penetrates into the epidermis, so that the applied crops have long-term residual effect, and there is a second peak of insecticidal mortality rate in more than 10 days, and it is rarely affected by environmental factors such as wind and rain.

3) Pest control: emamectin benzoate has incomparable activity against many pests with other pesticides, especially for Lepidoptera, Diptera, thrips super efficient, such as red banded leaf roller moth, Axiguami fumigataria, cotton bollworm, tobacco moth, diamondback moth armyworm, beet armyworm, fall armyworm, Spodoptera exigua, Spodoptera exigua, cabbage butterflies, cabbage borer, cabbage striped borer, tomato moth, potato beetle, Mexican ladybug, etc.

4) Main dosage forms:

There are two specifications of emamectin benzoate in our factory: domestic grade content of more than 60%, export grade content of 80%.

First, the process slag shed process is short. Compared with the five-step process, the process equipment and corresponding plants, pipelines, electrical appliances, instruments and other facilities are reduced by 40%, and at the same time, the number of operators is reduced, the cost is reduced, and the operation cycle is shortened.

Second, the synthetic yield is high. The total yield of emamectin benzoate was more than 60%, and the single consumption of avermectin was less than . The crude content can reach 70%. After purification and recrystallization, the quality can reach 80-90% of the level of fine products.

3. Low cost and high added value. The cost of raw materials is 2000 yuan kg discount.

Fourth, it can be operated on an industrial scale. The annual production scale can reach 10-30 tons.

Fifth, the sustainable launch of new products. On the basis of the production of emamectin benzoate industrial equipment, a small amount of investment and equipment can be added to produce acetaminamide avermectin with good market prospects and high added value. This equipment can also be used to produce heptamethyldisilazane, a supporting raw material required for the synthesis of emamectin benzoate.

Sixth, the technology is mature and reliable. This technology is the earliest introduction, development and development of emamectin benzoate experts and senior engineering and technical personnel in China, and has been promoted in China, all of which have been successfully put into production and have obtained good economic benefits.

The content of technology transfer includes: operating procedures, safety regulations, analysis procedures, a full set of process flow charts, standard equipment lists, non-standard equipment drawings, training technicians and operators, helping to start, and ensuring that qualified products are produced according to the design requirements.

1) Applicable crops (2) Mechanism of action (3) Pest control.

Quantitative analysis with HPLC (High Performance Liquid Chromatography). Chromatographic conditions: 25 cm, 5 m particle size KROMASIL-C18 stainless steel column; Mobile phase methanol-water (volume ratio 92:

8)；Velocity of flow; The UV detector wavelength is 254nm. The method is linear over the injection range and peak height. The value of the correlation coefficient (r) is.

The ** rate of emamectin benzoate analysis was 98% to 102%, and the coefficient of variation was.

Emamectin benzoate (full name: emamectin benzoate), white or light yellow crystalline powder, soluble in acetone and methanol, slightly soluble in water, insoluble in hexane. It is a new type of high-efficiency semi-synthetic antibiotic insecticide synthesized from the fermentation product avermectin B1, which has the characteristics of ultra-high efficiency, low toxicity (preparation is nearly non-toxic), low residue, pollution-free and other biological pesticides.

It is widely used in the prevention and control of a variety of pests on vegetables, fruit trees, cotton and other crops.