Is cellular immunotherapy reliable for patients with advanced cancer?

It's useless, and if you can't cure the disease, it's equal to losing both people and money.

In recent years, immunology has become one of the hot spots in the field of oncology research at home and abroad, and a large number of clinical studies have shown exciting results. As the deputy editor-in-chief of the Chinese Journal of Cancer Biology, Professor Luo Rongcheng said that there are two modes of cancer: one is "cell killing" (cell killing) and the other is "cell control" (cell regulation).

Traditional surgery, chemotherapy, radiotherapy and other methods belong to the former, which has a certain amount of harm to the patient's body; The latter aims to improve the body's biological response ability (including immunity) to control the development of tumors, with the least damage to patients and the greatest benefit, and immunity** is one of them. Tumor cells are very cunning, paralyzing the immune system by antigenic modulation or altering histocompatibility complex (MHC) expression, as if they were cloaked in camouflage. It is only possible to defeat the immune system if it is stronger than the tumor.

In the advanced stage of cancer, the treatment of advanced cancer with cellular immunity is simply high-tech. Western medicine will not cure diseases, and 80% of the cells in the human body are not their own, but it is reasonable to think about it, there are many patients, many cancers and 80% of the cells are other people's, and it is reasonable for people to be sick. People who do not understand the structure of the human body will think that another great science, the high science of Western medicine, will definitely bring down cancer for the benefit of future generations.

I still remember that the fog "water" haze and "dust" together, fooled the Chinese for more than 20 years, put people's ideas on the haze, and ignored that cool water beads will create diseases and cancer. Now the cells and immunity are combined, and the cells are not their own, but should be used on the patient. Immunity is its own immunity, such as ** outside, there is a special protective film, this film is particularly durable, the sun is not bad, scratching and scratching, a burden of scratching, will bleed, burn it, it is called a scar.

But if Western medicine puts these two things together, what will it achieve? Wait and see! Anyway, the Chinese are not afraid of death, although let's toss

1. The targeting is not clear, and the input has little effect: at present, the immune cell technology is not mature, the market is chaotic, and it is manifested as CIK, DC-CIK or NK, and the ordinary preparation process is used to improve various types of cancer.

2. The efficacy is not clear: often doctors or biological companies will ask you about special cases, how long have you survived with remission or tumors, but you have to know how large the sample size is to find out a special case.

3. The purity and phenotypic standards are not uniform: I want to complain the most, the immune cells prepared by the current process refer to a group of cells, the purity is up to 95%, and the less 70% is also, as for the role of this part of the unknown cells, no one has done the experiment yet, you ask why? The cell preparation process of each hospital is different, and the experiment can only represent that there are these types of cells in the cells made by their own process, but not all of them.

4. Pertinence: As far as I know, blood tumors have a better effect on immunity than solid tumors.

5. Is it a well-known hospital or a hospital with a military background, or a hospital that cooperates with a team led by a team in this field will be more reliable? I'm sorry, I'm not sure about this, but the technology I know, for example, the biological ** of Zhongshan Tumor is no different from what some biological companies I know, and the quality control is not even as good as the company's. It's late, so don't expect too much, if you're looking to improve your quality of life or live longer, you may be able to reach your goal.

If you want to live through the 5-year life cycle, you may not be able to achieve it. As far as I can see, for most patients, immune cell infusion** is still helpful in improving quality of life such as sleep, stamina, pain, appetite, etc. But other aspects such as prolonging the life cycle and even preventing tumor progression are limited.

Of course, most of the patients in the hospital are terminally ill, which can only represent the situation at this stage of the disease. <>

Dr. Li Yucong of the Department of Clinical Oncology pointed out in an interview that the 1-year survival rate of patients with stage 4 non-small cell lung cancer is only 14%, and the 5-year survival rate is 0%, the main reason is that most of the stage 4 tumors have spread to organs other than the lungs, such as bones, etc., and the options and results are limited.

An international study called impower150 found that the combination of immune** (atezolib), targeted drugs (bevacizumab) and chemotherapy** could prolong the progression-free survival and overall survival of patients with non-genetic mutant stage 4 non-small cell lung cancer (NSCLC) by nearly two months to a median of nearly two months and a median of one month to a month in the latter compared with targeted drugs and chemotherapy alone.

Genetic mutations are more effective.

Li Yucong continued to point out that the study also found that even if the above patients were accompanied by liver metastases, the overall median survival time was also improved, which could be extended by 4 months. For patients with EGFR or ALK gene mutations, although they have received relevant targets** but failed, but when immunization** is added to the second line**, their survival is significantly prolonged, indicating that this combination** is effective for patients.

The effect of lung cancer biological immunity** should be measured for the content of PDL1. The purpose of tumor immunity** is to stimulate and mobilize the body's immune system, enhance the tumor microenvironment, anti-tumor immunity, and thus control and kill cells. There are now several categories of immunity** against tumors, especially lung cancer

For PDL1 inhibitors and immunoassay inhibitors, the currently domestically marketed durvalumab and atezolizumab for PD1 are pembrolizumab, nivolumab, camrelizumab, sindilil and terprelil. The effect of immunity is mainly to detect the content of PDL1, such as the content of PDL1 TPS is greater than 50%, and the effect of immune checkpoint inhibitors alone is better, such as PDL1 positive, that is, TPS positive in 1 to 49%, the effect of this monotherapy immune checkpoint inhibitor is worse, but if he combines chemotherapy, the effective rate of ORR will be greatly improved, for PDL1 is negative, referring to less than 1% of patients, it is recommended that chemotherapy combined with immunoassay inhibitors, to perform anti-tumor**.

It's better to go to see traditional Chinese medicine, because modern Western medicine can only rely on radiotherapy and chemotherapy, so that the patient can't withstand the poison and declares it a failure, thus delaying the opportunity.

How to say it, it's already in the advanced stage, ** or something is to comfort the family, do a good job of dying comfort, chemotherapy is not effective.

Small, the patient is not guilty, the effect is good, but the cost is high! It is not bad to reduce the lesion after appropriate radiotherapy first, and then carry out biological immunity**!

It can prolong the life cycle of the patient.

Cell** is an emerging ** model with significant curative effect, and it is a new ** method of autoimmune anti-cancer. It is a method of using biotechnology and biological agents to culture and expand the immune cells collected from the patient's body in vitro and then infuse them back into the patient's body to stimulate and enhance the body's autoimmune function, so as to achieve the purpose of the first class.

Cells can be used for a variety of diseases, and the effect is significant:

1. Chronic diseases (chronic renal failure, digestive disorders accompanied by decreased function of the stomach, gallbladder and pancreas, chronic constipation, chronic liver failure, intervertebral disc damage, spinal pain, premature joint wear. ）

2. Degenerative diseases (disease states in which neurons of the brain and spinal cord are lost, common diseases include ataxia, cerebellar atrophy, Parkinson's, multiple sclerosis, etc.).

3. Immune diseases ("autoimmune diseases" are diseases caused by the immune system's immune system responding to its own components, causing damage. Including: lupus erythematosus, rheumatoid arthritis, juvenile diabetes, a variety of ** diseases, etc. ）

4. Malignant neoplastic diseases (the principle of "killing tumor cells with the body's own immune cells" can greatly enhance the immune function of the human body and inhibit the growth of tumor cells. ）

5. Anti-aging and beauty (using the regeneration and repair function of cells to replace senescent cells in tissues in time, and also activate the growth of cells.) It can be used for **, wrinkle removal, etc. ）

7. Other diseases (liver cirrhosis, cerebral palsy, diabetes, hepatitis, necrosis of the femoral head, etc.) ）

My neighbor did not choose chemotherapy after cancer surgery at the beginning of last year, but followed the introduction and made immune cells**, which was done in a company called Nanjing Huaao Biotechnology, and recovered well in the later stage, and is now in good spirits.

Cancer immunity is a new tumor method that has emerged in recent years, and the mechanism of action is mainly to restart the patient's immune system to enhance the anti-tumor immune effect. At present, there are several methods including PD-1 and PD-L1 inhibitors, cellular immunity**, vaccines, etc., which are smaller than traditional chemotherapy, and more PD-1 and PD-L1 inhibitors are used in terms of efficacy.

Clinical trials have shown that immunity has achieved good efficacy in lung cancer, esophageal cancer, melanoma, etc. In particular, the combination of chemotherapy or other targeted** drugs can effectively control tumor progression and prolong patient survival.

Everyone must develop a good eating habit in life, and must pay attention to their own work and rest, and never stay up late, because staying up late is very harmful to people's bodies. What do you know about immunity** in advanced lung cancer?

Here I will give you a detailed introduction, many people may feel that this disease is very serious, if the patient's condition is not controlled, then to a certain extent, it will affect everyone's life, so it should be detected as soon as possible, and then carried out as soon as possible, it is definitely recommended that you go to the hospital to do a detailed examination, and the relevant ** plan is actually more, but the conventional ** method is to use surgical surgery ** and chemotherapy. However, most patients find that their body has developed to an advanced stage when they find that they have tumors, and at this time they cannot undergo surgery, and can only use conservative methods to carry out it, and immunity is actually a very effective way.

Maybe many people don't know much about this method, because the method that everyone usually knows more is surgery and chemotherapy. However, chemotherapy has a greater impact on patients, and most patients do not want to undergo chemotherapy because chemotherapy is relatively large. At this time, immunity can be used, which is currently the most effective method, and great progress has been made in the medical community.

At this time, the patient must cooperate with the doctor to do a good job, and the patient does not need to feel very nervous at this time, because most people feel that their disease has no way to be cured. Patients must keep their emotions calm at this time, because the probability of ** is still relatively large, which can allow you to relieve the pain.

In the advanced stage of lung cancer, you need to do conservative **, use the body's immune system to sterilize, and do radiotherapy, control through drugs, understand the ** plan, you must have good eating habits, and you can't stay up late.