The result is whether thalassemia with SEA type gene deletion Southeast Asian type is heterozygous

Updated on parenting 2024-08-10
3 answers
  1. Anonymous users2024-02-15

    Not severe, this is a genotype of mild thalassemia.

    People have four globin genes, and the deletion of SEA causes the patient to lose two of them, but the other two are normal, and the heterozygous is normal and not normal, so it is still mild.

    Patients may have mild anemia, but there are usually no other problems. The patient's spouse was before or at the beginning of the woman's pregnancy.

    Thalassemia and blood routine should be thoroughly checked.

    Normal is not a basis for ruling out thalassemia in a spouse.

    The result was a standard thalassaemia, commonly known as mild thalassaemia, which had little effect on the physical health, intelligence, and life expectancy of the person. Usually not anemic or mildly anaemic.

  2. Anonymous users2024-02-14

    Refers to a specific mutation of a gene. Heterozygous means that two genes on one chromosome are good and the other has a SEA mutation.

    People have four alphaglobin genes distributed on two chromosomes (number 16), each with two genes, one from the father and one from the mother. Now both genes on one chromosome are missing (but the other is normal (AA)).

    Usually mild thalassemia does not need special **, because there is no complete cure at present, mild patients have asymptomatic or mild anemia, the spleen is not large or mildly large, the course of the disease is good, can survive to old age, mild generally does not become serious, regularly go to the hospital to check the blood.

    The impact on the next generation, if one of the husband and wife has thalassemia minor, the fetus only has a 1 2 chance of mild thalassemia, and the remaining 1 2 is a normal fetus and will not give birth to a thalassemia major fetus, the genetics of thalassemia are not related to sex, and the incidence of male and female fetuses is equal. If the husband and wife are carriers of homothalassaemia, each pregnancy, the child has a 1 4 chance of being normal, 1 2 of the children being carriers, and 1 4 of a 4 of being thalassemia major. Therefore, when the spouse gets married and has children in the future, he or she needs to undergo a genetic test for thalassemia and prepare for pregnancy under the guidance of a doctor.

  3. Anonymous users2024-02-13

    Hello: Thalassemia is a group of hemolytic anemias, which can be divided into two categories: thalassemia and -thalassemia, which are caused by defects such as deletion and mutation of -globin gene or -globin gene, respectively.

    The detection of SEA deletion indicates that two of the four globin genes are lost and the other two are normal (because they are heterozygous). Thalassemia mild.

    Zhonghai anemia is a hereditary disease, which is mostly found in the southern coastal areas of China, namely Liangguang, Hunan, Hubei, Sichuan, Zhejiang, Fujian and Taiwan. This disease is a congenital anemia in which the lifespan of red blood cells is shortened due to abnormalities in the quantity and quality of hemoglobin in red blood cells. There is currently no special method for this disease.

    Only intermittent transfusions or transfusions of concentrated red blood cells are available to replace the deficiency of red blood cells. Patients with thalassemia are prone to various infectious diseases due to long-term anemia, resulting in a lack of oxygen and other nutrients in the body, low immunity, and various infectious diseases.

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