What is the difference between Parkinson s and essential tremor?

1.Parkinson's disease is a degenerative disease of the central nervous system that occurs in middle age and above, mainly in the substantia nigra and striatum of the brain. The pathophysiological changes are dopaminergic neuronal degeneration in the substantia nigra, which leads to dopamine deficiency in the brain, causing a series of pathophysiological changes, among which the hyperexcitability of the subthalamic nucleus and the medial globus pallidus is an important feature of Parkinson's disease.

If Parkinson's disease is not detected early, the condition will further deteriorate in the early stage, and even lead to the loss of labor and the inability to take care of oneself.

2.Essential tremor is a movement disorder with tremor as the only manifestation, which is mainly manifested as hand or head action and postural tremor, which is aggravated during mental tension and is not accompanied by muscle stiffness and slowness. Because essential tremor and Parkinson's disease are not well understood, they can be confusing.

3.Essential tremor features:

Patients with essential tremor have no decreased movement, increased muscle tone, and impaired postural reflexes, no impairment of voluntary combined movements, and no impairment of body posture and stability, and no dysmetria, ataxia, and nystagmus.

Essential tremor may resolve within 2 to 4 hours of drinking, but symptoms are worse the next day.

Essential tremor often has voice tremors but no loss of speech.

Taking propranol, primidone, and diazepam** is effective.

Taking drugs such as levodopa and medopa is ineffective.

4.Tremor features of Parkinson's disease:

Tremor in Parkinson's disease is resting tremor that is not evident during active movement. It usually starts at the distal end (finger) of one upper limb and gradually extends to the ipsilateral lower limb and the contralateral upper and lower limb. The jaw, lips, tongue, and head are usually the last to be affected.

The tremor is coarse, with a frequency of 4 8 seconds (4 8 Hz), which can be temporarily controlled but not persistent, aggravated by agitation and fatigue, and disappeared during sleep.

5.The expert emphasized:

Essential tremor, also known as familial tremor. Due to the lack of understanding of essential tremor, the clinical diagnosis rate of essential tremor is not high, and some middle-aged and elderly people with essential tremor are worried that they have Parkinson's disease, whether they have essential tremor or Parkinson's disease, and need to be carefully examined by professional doctors to distinguish it.

Essential tremor and Parkinson's disease are two completely different diseases, and the difference is that:

1. Pathogenesis: The pathogenesis of essential tremor is currently unknown; The pathogenesis of Parkinson's disease is related to dopamine deficiency in the substantia nigra of the midbrain;

2. Clinical manifestations: essential tremor is mainly manifested as postural tremor and action tremor; Parkinson's disease presents with resting tremors, stiffness, and slowness.

Parkinson's is a common condition in older adults Essential tremor is a motor disease.

Essential tremor is a disease in which tremor is the main manifestation, and patients do not have symptoms such as decreased movement, expressionlessness, and stiffness of limbs, and the symptoms are milder and less severe than Parkinson's disease. Secondly, the tremor of patients with essential tremor is active postural tremor or action tremor, that is, the tremor occurs when moving or holding the position, and the tremor decreases or even disappears when the tremor is kept quiet, such as watching TV, staying still, or sleeping. The tremor of patients with Parkinson's disease is static, that is, when sitting still and quiet, the hands begin to shake incessantly, and the symptoms of rubbing pills or counting money appear.

So the difference between Parkinson's disease and essential tremor is obvious. If essential tremor is diagnosed, it is much milder than Parkinson's disease, and if it does not affect the patient's life, there is no need to take medicine. Even if essential tremor develops to a more severe condition, that is, it affects the movement of the patient's hand, the tremor is more obvious, and there will be no obvious impact on the life of patients with Parkinson's disease, or even a decrease in the quality of life.

Essential tremor is relatively benign and progressive.

Tremor is Parkinson's disease.

One of the main clinical manifestations. In the early days, Parkinson's disease was also called tremor paralysis, so many people mistakenly thought that Parkinson's disease was tremor, but in fact, these two concepts are completely different. Parkinson's disease can manifest as tremor, and many patients present with tremor, but in fact, tremor is not the only manifestation of Parkinson's disease, Parkinson's disease is mainly manifested by slow movement, reduced movement, gait, walking posture disorders.

Patients may also have no tremors, only stiffness and bradykinesia.

Tremor is a group of symptoms that can occur in Parkinson's disease, other diseases or normal conditions, such as physiological tremor in normal people with nervousness, agitation, anxiety, and emotional instability. Other drug factors can also cause tremors, as can other metabolic or muscle disorders in the body, so Parkinson's disease and tremor are not a disease.

The difference between essential tremor and Parkinson's disease is reflected in the following aspects:

1. Age of onset, essential tremor can occur at any age, with slow progression, insidious onset, or long-term remission; Parkinson's disease is common in middle-aged and elderly people, with insidious onset, slow progression, and no long-term remission process. Clause.

2. Characteristics of tremor, essential tremor is manifested as postural and action tremor, which is seen in one upper limb or both upper limbs; Tremor in Parkinson's disease, which appears as a resting tremor, can start in one upper limb, involve the ipsilateral lower extremity, and then spread to the contralateral upper and lower extremities. Clause.

3. Other signs, idiopathic tremor has no other positive signs except tremor; In addition to tremor, Parkinson's disease can also have positive signs such as muscle rigidity, bradykinesia, and postural balance disorders.

Essential tremor and Parkinson's disease are two completely different diseases, and their differences are: 1. Pathogenesis: The pathogenesis of essential tremor is currently unknown; The pathogenesis of Parkinson's disease is related to dopamine deficiency in the substantia nigra of the midbrain; 2. Clinical manifestations:

Essential tremor is mainly manifested as postural tremor and action tremor; Parkinson's disease presents with resting tremors, stiffness, and slowness.

One of the diseases that Parkinson's needs to distinguish is senile tremor, also known as essential tremor, which and Parkinson's are also manifested as tremor, but it's different from it. Generally speaking, both diseases can be treated with medication and surgery. Drugs** are mainly drugs for Parkinson's disease, the most commonly used are levodopa, and coenzyme Q10.

For essential tremor, primidone is most commonly used. Surgery can be performed with DBS, which is an electrode into the brain to control this involuntary movement. Hope it helps.

Essential tremor is generally manifested as tremor of the limbs, especially in the head and hands, and some patients also have tremor of the lower limbs, which is generally postural tremor, not accompanied by stiff facial expressions, slow movement and other manifestations. The tremor of Parkinson's disease is manifested as a resting tremor, which is less obvious during general activity. In addition, in addition to tremor, Parkinson's disease is also accompanied by stiffness of facial expression, abnormal posture and gait, decreased arm swing, slow movement, difficulty in starting, etc.; There are also some sleep disorders, constipation, abnormal sense of smell, etc., and non-motor symptoms can also be combined.

1. Distinguish according to the pathogenesis.

The pathogenesis of Parkinson's disease is related to the deficiency of dopamine in the substantia nigra in the midbrain, which is a geriatric functional decline disease, which is a chronic disease that will affect normal life, and the probability of complete ** is not large, and it is generally easy to occur in the elderly. The pathogenesis of essential tremor is not yet clear, it may be caused by insufficient blood supply to the brain, or it may be caused by genetic factors, and the characteristic tremor will gradually worsen over time, and if measures are not taken in time, it will seriously affect the life and work of patients. Essential tremor can occur in both older and younger people.

2. Distinguish according to clinical symptoms

Parkinson's is a resting tremor, resting tremor refers to a tremor of 4 to 6 hertz when the patient is stationary and does not move, in addition to this resting tremor, Parkinson's patients will also have common symptoms such as slow movement, muscle stiffness, and posture maintenance disorders. Essential tremor has two symptoms: postural tremor and movement tremor. Postural tremor is characterized by a marked flutter of the hand when it is held in a certain positionAction tremor is the most characteristic manifestation of essential tremor, which is mainly manifested as obvious tremor when the hand completes a certain action.