Can acute myeloid leukemia be cured with only chemotherapy and no bone marrow transplantation?

Chemotherapy is only a symptom but not a cure, and chemotherapy drugs cannot kill all leukemia cells, especially the leukemia cells that remain in the leukemia shelter, which is the root cause of leukemia after remission. There are three main disadvantages: (1) the generation of primary drug resistance, secondary drug resistance, and the generation of multidrug resistance genes will eventually be unavailable. (2) Chemotherapy drugs not only kill leukemia cells, but also kill a large number of normal cells in the human body and cause gastrointestinal side effects, liver and kidney damage, complications of various systems, etc.

3) Decreased immune function.

The advantages of leukemia in traditional Chinese medicine are (1) syndrome differentiation and treatment in traditional Chinese medicine, through overall regulation, improve the patient's symptoms, improve the body's ability to resist disease, and benefit the patient's disease. (2) Traditional Chinese medicine has a attenuating and synergistic effect on chemotherapy drugs against leukemia, especially on gastrointestinal reactions. (3) To prevent the occurrence of cerebral white, some opening drugs and heat-clearing and detoxification drugs of traditional Chinese medicine have similar effects with intrathecal injection of methotrexate.

It depends on what type of leukemia the patient is, the current level of medical care, many types of leukemia have been actively treated, including Western medicine and traditional Chinese medicine, and many patients can be treated without bone marrow transplantation. By the way, bone marrow transplantation is theoretically a method of leukemia, but the actual clinical effect is not ideal.

Hematopoietic stem cell transplantation is currently recognized as the only way to treat leukemia in the world, but it is expensive and risky.

Bone marrow transplant is one of the most effective means of leukemia, but leukemia is still possible after bone marrow transplantation, why is that? What should I do after leukemia**? Here is a detailed introduction from the experts of the global hospital network.

Why is leukemia after bone marrow transplantation**Leukemia after bone marrow transplantation** is one of the important factors affecting the efficacy of bone marrow transplantation. It reduces the long-term survival rate of bone marrow transplant** leukemia and is a major life-threatening problem for patients after bone marrow transplantation. The rate of leukemia after allogeneic bone marrow transplantation is about 20% to 30%.

Leukemia** is mainly caused by incomplete clearance of leukemia cells during bone marrow transplantation. That is, the large number of leukemia cells remaining in the body is related to the weak anti-leukemia effect of the graft after bone marrow transplantation. Currently, research on leukemia by detecting minimal residual disease after bone marrow transplantation is being explored.

What to do after bone marrow transplantation, improve the bone marrow transplantation pretreatment program, strengthen the strengthening of leukemia patients before bone marrow transplantation, choose the best time for bone marrow transplantation, and induce the graft leukemia effect, etc., may be helpful in reducing the incidence of leukemia after bone marrow transplantation. In leukemia** after bone marrow transplantation**, for acute leukemia, remission is generally first induced by chemotherapy, followed by a second bone marrow transplant, and in some cases, a second bone marrow transplant can be performed directly without induction of remission. For patients who are in poor condition and are not expected to tolerate a second bone marrow transplant, only supportive and symptomatic can be done.

The rate of re-induction of remission after bone marrow transplantation** is 50% in acute lymphoblastic leukemia and even lower in acute myeloid leukemia. In patients who have undergone a second bone marrow transplant**, the long-term disease-free survival rate is only about 10%. For patients with chronic myeloid leukemia after bone marrow transplantation, the method of injecting interferon combined with transfusion of peripheral blood lymphocytes from donors has been able to achieve "**" (malignant clone disappearance) in some patients.

If this method is not effective, drugs such as hydroxyurea can also be used to control the condition, but the most active and effective method is still a second bone marrow transplant.

For the question of what to do after leukemia bone marrow transplantation, you can go to the leukemia section and the leukemia specialist hospital section and the leukemia symptoms section, these three sections summarize all kinds of questions about leukemia and common sense examination, among which the leukemia section is mainly to introduce the common problems related to leukemia, the leukemia specialist hospital section introduces you to the common problems related to leukemia hospitals, and the leukemia symptoms section introduces you to the leukemia examination and diagnosis, Leukemia symptoms and other aspects.