Try to compare the similarities and differences between glycolysis and aerobic oxidation from the fo

Glycolysis Aerobic oxidation of sugars Cytosol Cytosol, mitochondrial reaction conditions Anaerobic or hypoxic net production by phosphorylation and oxidative phosphating at substrate level 36 38 ATP Physiological Significance Rapid energy supply.

The products are different.

The end products of aerobic oxidation of sugars in any organism are carbon dioxide and water. There are two types of anaerobic oxidation of sugars: anaerobic oxidation in many higher plants will ferment to produce alcohol and carbon dioxide hail; Anaerobic oxidation in animals such as humans produces lactic acid.

2.The energy emitted is different.

Aerobic oxidation is done because the presence of oxygen will make the sugars more fully oxidized and release more energy; In the process of anaerobic oxidation, the sugars can only be oxidized to the stage of pyruvate production, and less energy is released.

3.The conditions under which the response occurs.

When engaging in very strenuous sports or rapid bursts, such as weightlifting, 100-meter sprint, wrestling, etc., aerobic metabolism is not possible.

4.The nature is different.

Anaerobic oxidation of sugar, also known as glycolysis, is the process of decomposing glucose or glycogen into lactic acid while producing a small amount of ATP under anaerobic or hypoxic conditions. Aerobic oxidation of sugar is the main way for the oxidative decomposition of sugar in the body to produce ATP in large quantities.

5.The characteristics are different.

The whole process of glycolysis is carried out without the involvement of oxygen. The whole process of aerobic oxidation of sugar is aerobic participation.

There are three stages of aerobic oxidation of sugar:

In the first stage, glucose is broken down into pyruvate through the enzyme pathway.

In the second stage, pyruvate enters the mitochondrial source and is oxidatively decarboxylated to acetyl-CoA (CoA).

The third stage is the tricarboxylic acid cycle and oxidative phosphorylation.

The above content reference: Encyclopedia - Aerobic oxidation of sugars.

The landlord may have confused the concepts of "glycolysis" and "enzyme pathway" in the case of hypoxia, the process by which glucose produces lactic acid.

Pathway: The process by which glucose is broken down into pyruvate.

Therefore, glycolysis must, attention is necessary, to be carried out in the absence of oxygen; The fermentation pathway has no requirement for oxygen, and can be carried out with and without oxygen; The tricarboxylic acid cycle must be carried out under aerobic conditions.

Supplementary question answer: Each tricarboxylic acid cycle yields 1 FADH2 and 3 NADPHWhen there is oxygen, NADPH enters the mitochondria and is oxidized by O2 to complete the tricarboxylic acid cycle; In the absence of oxygen, NADPH is oxidized by pyruvate directly in the cytoplasm and cannot enter the mitochondria to participate in the tricarboxylic acid cycle, at which time, pyruvate is reduced to lactic acid, which is called glycolysis.

Glycolysis refers to the process of breaking down glucose or glycogen into pyruvate, ATP, and NADH+H.

This process is accompanied by the generation of a small amount of specialized ATP. This process takes place in the cytoplasm and does not require oxygen, and each reaction step is basically catalyzed by specific enzymes. Under hypoxic conditions, pyruvate can be catalyzed by lactate dehydrogenase, and the hydrogen removed from triose phosphate can be reduced to lactic acid.

The oxidative decomposition of sugar under aerobic conditions is called aerobic oxidation of sugar, and pyruvate can be further oxidized and decomposed to form acetyl CoA into the tricarboxylic acid cycle to generate CO2 and H2O.

Aerobic oxidation and glycolysis of sugars are exactly the same in many of the initial steps, except that after the decomposition into pyruvate, there are differences due to different oxygen supply conditions.

Glycolysis consists of a total of 10 sequential steps, all catalyzed by the corresponding enzymes.

The total reaction was: glucose + 2ATP + 2ADP + 2PI + 2NAD + 2H - 2 pyruvate + 4ATP + 2NADH + 2H + + 2H2O

Pyruvate (CH3Cocooh) + 2NADH — reversible — > lactate (CH3CHOHcoOH) + 2NAD+