What factors can affect elevated aminotransferases?

As a type of enzyme, aminotransferases play an important role in amino acids, but mainly in the liver, and are widely distributed throughout the body. Elevated aminotransferases indicate the possibility of liver disease, but it is not absolute, and it requires a combination of other tests and tests to determine whether the condition is triggering. For the factors that cause the elevation of aminotransferases, I think they mainly include some pathological diseases and poor physiological status, and the symptoms are not caused in time.

1. Alcoholic liver is one of the triggers

Alcoholic liver is known to be a liver lesion caused by heavy drinking and alcoholism, long-term alcoholism can cause hepatocyte degeneration or necrosis, and develop into liver cirrhosis, and long-term excessive alcohol can lead to a large number of hepatocyte necrosis in the body, causing liver failure. If the patient has a history of long-term alcohol consumption, this can lead to increased aminotransferases in the blood and liver, and the main symptoms are abdominal pain, general weakness, loss of appetite, and weight loss. <>

2. Autoimmune liver disease cannot be ignored

In addition to some external factors, self-physical factors can also lead to elevated aminotransferases, and autoimmune liver disease is typical. Autoimmune liver disease occurs because the liver is attacked by the autoimmune system and then causes hepatocyte necrosis and inflammation, which mainly occurs in women, and if left unchecked, it may develop into cirrhosis or liver cancer. It is important to note that in patients with autoimmune liver disease, in addition to elevated aminotransferases, autoantibodies will also appear in the serum to fight the condition.

Third, viral infection and motor factors are also triggersCause.

Infectious diseases cause hepatocellular lesions in the body when infected by a virus, resulting in elevated aminotransferases. If you receive a more serious bacterial infection, such as sepsis, it can cause damage to the liver. Moreover, in terms of exercise, improper exercise will cause an increase in transaminases, and when the body is too tired and insomnia occurs, it will also cause different degrees of elevated aminotransferases.

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Elevated aminotransferases represent liver damage, which can be caused by many reasons, such as acute cholecystitis, gallstones, acute pancreatitis, hepatitis B cirrhosis, severe infection, heart failure, etc., in addition to food poisoning, pesticide poisoning, etc., some drugs can also lead to an increase in aminotransferases. It is recommended to go to the hospital for medical treatment.

There are many reasons for high aminotransferases, such as fatigue, lack of sleep, alcohol consumption, drugs, fatty liver, etc. When viral hepatitis occurs in the liver, all kinds of acute and chronic viral hepatitis can lead to elevated alanine aminotransferase.

Behaviors such as staying up late often, eating irregularly, and liking to eat spicy foods can all lead to elevated aminotransferases, and it is recommended to maintain good lifestyle habits.

Viral infections can cause elevated aminotransferases, such as hepatitis A virus, hepatitis B virus, hepatitis C virus, etc. There are also drugs, and some drugs can cause transaminase height if taken for a long time. Drinking alcohol can also lead to elevated aminotransferases and staying up late.

Elevated aminotransferases are common in various types of hepatitis, hepatitis, usually liver tissue inflammation and necrosis, which will cause liver cells to release transaminases into the blood, so people with hepatitis are generally high in transaminases.

What is the cause of high aminotransferases? First of all, we have to understand the existence of transaminases, it mainly exists in cells, especially liver cells, in addition to the liver, aminotransferases also exist in the tissues and cells of brain, heart and other organs, it is a special protein, once the aminotransferase is high for a long time, it will reflect some problems, so what factors cause high aminotransferase? Let's take a look.

What is high aminotransferase?

Under normal circumstances, aminotransferases only stay inside the cell, and only when the cells are destroyed, the aminotransferases have a chance to run outside the cells and enter the human bloodstream.

Since aminotransferases exist in a large number of liver cells, once the transaminase test is high, it can reflect liver problems, but it does not mean that you have hepatitis, which needs to be paid attention to.

What causes high aminotransferases?

The transaminase value of normal people is not high, so what factors cause the transaminase to be high? Everything has a cause and effect, and the following conditions can cause high aminotransferase values:

1. Caused by viral hepatitis.

Liver health is closely related to the level of transaminase values, and patients with viral hepatitis indicate that liver cells are damaged, and the transaminase values must be high at this time. There are also other abnormalities in liver function that can lead to elevated aminotransferases.

2. Drug-induced liver damage.

When taking certain drugs, it will hurt the liver, once the liver cells are damaged, the transaminase value will inevitably increase, and the long-term use of contraceptives, erythromycin, sleeping pills, tuberculosis drugs, etc. will damage the liver, but after stopping the drug, the transaminase will slowly become normal again.

3. Poor diet and rest.

Long-term poor diet or staying up late will affect the normal function of our liver, which will damage liver cells and lead to elevated aminotransferases. In addition, daily overexertion can also lead to this kind of situation.

4. Caused by biliary tract diseases.

Aminotransferases need to be excreted from the bile ducts, and if you have biliary diseases, such as cholecystitis, bile duct obstruction, etc., it will affect the normal discharge of transaminases, which will lead to an increase in transaminases.

There are many reasons for the elevation of aminotransferases, including diseases, diet, lifestyle, etc. Long-term high-protein, high-cholesterol, and greasy diets can cause elevated aminotransferases. Aminotransferases are also elevated in obese people.

Drinking a lot of alcohol, engaging in high-intensity exercise, working intensively, living a stressful life, staying up late, not getting enough sleep, and mood swings can all lead to elevated aminotransferases. Diseases that cause elevated aminotransferases include hepatitis B, alcoholic hepatitis, biliary obstruction, fatty liver, epidemic, acute myocardial infarction, dermatomyositis, etc. Whatever the cause of the elevated aminotransferases, remove ** to avoid worsening liver damage.

The general reason is that you have taken a lot of antibiotics, and the *** of this drug is very large, which is just one of the symptoms, and you have to stop taking antibiotics and observe other conditions of the body.

First, there is inflammation in the body, secondly, suffering from myocarditis, thirdly, there is a lack of nutrients in the body, fourthly, there is a lack of certain exercise activities, and fifth, suffering from pneumonia.

It is likely to be caused by liver damage, or it may be caused by improper diet, which may be related to the usual drinking habits.

Aminotransferases are widely found in the liver, heart, lungs and other organs, the normal value is 0-40u l, once the normal value is exceeded, it is considered that the aminotransferases are high, the production of high aminotransferases may mean that these tissues and organs are disordered, and the elevated aminotransferases are most common in liver diseases, such as common viral hepatitis, alcoholic hepatitis, fatty liver, drug-induced hepatitis, etc. But it is not absolute, because some non-disease ** elements can also cause high aminotransferases. Therefore, when you find that aminotransferases are elevated during the physical examination, you should first find out**in a timely manner after clarifying**, the details are as follows:

There are many causes of elevated aminotransferases, and hepatitis cannot be diagnosed based on elevated aminotransferases alone, but should be thoroughly analyzed in conjunction with symptoms, signs, and other test results to make a correct diagnosis. To determine the development of hepatitis, the following three must be present at the same time. That is, there are symptoms and signs of hepatitis (such as low-grade fever, anorexia, nausea, vomiting, fatigue, poor appetite, liver swelling and pain, etc.) and clinical diagnosis (such as acute jaundice, chronic protracted type, etc.); elevated serum aminotransferases; Etiological diagnosis (hepatitis A antibody is A, hepatitis B surface antigen, E antigen, and core antibody are B).

Some people have high levels of pure aminotransferases, and it is not ruled out that they may be interfered with by factors such as excessive alcohol consumption, strenuous exercise, night shifts, colds, or oral medications before testing. "Chongqing Nonggan's Drink" is very good at lowering enzymes.

Elevated aminotransferases are most indicative of hepatitis. However, aminotransferases can also be elevated for the following reasons:

1. For healthy people, the level of aminotransferases may also temporarily exceed the normal range, such as working overtime the night before the physical examination, not sleeping well, overworking or strenuous exercise, which may make the aminotransferases temporarily high.

2. Fatty liver can also cause an increase in aminotransferases, because fatty liver will cause liver dysfunction in the liver and lead to continuous damage to liver cells, so it will also cause continuous increase in aminotransferases.

3. In the acute attack of biliary tract diseases such as cholecystitis and cholelithiasis, in addition to fever, abdominal pain, nausea, vomiting, jaundice and other conditions, it can also cause high blood bilirubin and aminotransferase.

4. Liver damage caused by other diseases.

Elevated aminotransferases should prompt a visit to the hospital for a detailed examination.

Consult a doctor.

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Medications, staying up late, drinking, poor rest, and greasy diet will all cause temporary fluctuations in aminotransferases, but after excluding the above factors, they will return to normal. In addition, there are some diseases that can cause abnormal liver function.

1. Diseases of the liver itself, especially various types of viral hepatitis B, cirrhosis, liver abscess, liver tuberculosis, liver cirrhosis, steatohepatitis, Wilson's disease, etc.

2. In addition to the liver, other organs and tissues of the body also carry this enzyme, so beware of myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, Japanese encephalitis, common myositis, acute sepsis, enteric typhoid, encephalitis, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, crush syndrome, etc.

3. Diseases of bile ducts, gallbladder and pancreas, and obstruction of bile ducts.

4. When liver cirrhosis and liver cancer cirrhosis are active.

5. When there is an emergency attack of cholecystitis and cholelithiasis of biliary tract diseases.

6. In the case of acute myocardial infarction, myocarditis and heart failure in heart disease, alanine aminotransferase and aspartate aminotransferase are high.

It is also possible for aminotransferase levels in healthy people to temporarily exceed the normal range. Strenuous exercise, overexertion, or a recent history of fatty foods can cause transaminases to be temporarily high. If you work overtime the night before the transaminase test, don't get a good night's sleep, or eat fried food for breakfast before the exam, the test results may be out of the normal range.

A person who has just run a few laps on the playground immediately has his aminotransferase levels checked, and the results may also be higher than normal.

Kindergarten physical examination aminotransferases are significantly increased, this is considered to be liver disease, the most common is liver damage caused by drugs, can also be seen in infection with cytomegalovirus, infection with hepatitis B virus, so you need to go to the hospital for further examination, generally need to do hepatitis B five, cytomegalovirus examination, to clarify the type of specific disease, if it is infected with cytomegalovirus, then it is necessary to use antiviral drugs as soon as possible**, generally commonly used acyclovir tablets**, if there are other diseases, then it needs to be symptomatic**.

The causes of high aminotransferases are as follows.

1. Liver diseases, especially various types of viral hepatitis B, cirrhosis, liver abscess, liver tuberculosis, liver cirrhosis, steatohepatitis, Wilson's disease, etc., can be the cause of high transaminases.

2. In addition to the liver, other organs and tissues of the body also carry this enzyme, so when myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, Japanese encephalitis, common myositis, acute sepsis, enteric typhoid, encephalopathy, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, crush syndrome, etc., high transaminases in the blood can also be seen.

3. Since transaminases are excreted from the bile ducts, if there are diseases of the bile ducts, gallbladder and pancreas, and bile ducts are blocked, the transaminases can also be high.

4. When liver cirrhosis and liver cancer cirrhosis are active, alanine aminotransferase can usually be high, and it should be active.

5. When the biliary tract disease cholecystitis and cholelithiasis are attacked, there are often fever, abdominal pain, nausea, vomiting, jaundice, high blood total bilirubin and alanine aminotransferase.

6. In the case of acute myocardial infarction, myocarditis and heart failure in heart disease, alanine aminotransferase and aspartate aminotransferase are high, and hepatitis B patients often have chest pain, palpitations, shortness of breath and edema. Cardiac tests show positive signs and ECG variants.

7. In addition, some infectious diseases, such as pneumonia, typhoid, tuberculosis, infectious monocyte enlargement, etc., have high alanine aminotransferase.

If the aminotransferases are high, do not worry too much, but also look at other test results, as well as the current symptoms, and go to a regular hospital for detailed consultation and treatment.