What is the short plan that the doctor said when doing IVF? What s different from the long plan?

For patients with regular ovulation, a long natural cycle regimen can be chosen, and for patients with irregular ovulation, an oral contraceptive prolongation regimen can be chosen. The natural cycle long regimen is generally from the 1st to 2nd day of menstruation, or 5-7 days after ultrasound monitoring ovulation. The lengthened regimen of oral contraceptives is generally on the 16th to 18th day after oral contraceptives, and there is no abnormality in B-ultrasound, and the use of dufferin is started to reduce the condition.

Generally, after about 14-20 days, the standard of downregulation is reached, and after the standard is reached, the drug is used to induce ovulation. Generally, it takes about 10-14 days for follicles to mature, and then hcg ovulation injection, 36-38 hours after the injection, the male sperm is retrieved at the same time as the egg retrieval, and then handed over to the embryo laboratory personnel for embryo culture, embryo culture is followed by embryo transfer, and the remaining embryos are frozen. Blood was drawn 14 days after the transplant to check the blood for HCG, and if the HCG is positive, it means that the pregnancy was successful.

Fetal preservation after pregnancy** is confirmed, followed by obstetric follow-up.

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The short regimen is indicated primarily for patients who are older, have a diminished ovarian reserve, or who do not respond well to a longer regimen. As the name suggests, the short plan takes a shorter period of time, which is basically similar to the menstrual cycle, and takes about 10-15 days before and after; The long regimen is one of the most commonly used ovulation induction regimens and is mainly used in patients who are in a good condition and have normal ovarian function and can respond appropriately to stimulation medications.

The long-term regimen generally starts from the 18th to 21st day of the patient's menstrual cycle (mid-luteal phase) before the formal stimulation of the patient's menstrual cycle, and then starts to use stimulation drugs for ovulation induction around the 3rd day of the formal menstrual stimulation cycle, during which it needs to be used irregularly.

b Ultrasound monitoring of follicle growth and measurement of estrogen content. After that, the use of stimulation drugs can be adjusted in real time according to the monitoring situation, and HCG can be injected when the follicles are mature, and finally the egg retrieval surgery can be performed about 36 hours after the HCG injection.

The long regimen is generally suitable for patients with good ovarian reserve, and is characterized by the synchronization of follicles, the relatively uniform size of the follicles, and the stable hormone levels in the body. Generally, multiple high-quality eggs can be obtained, which can improve the pregnancy rate, and is the most commonly used ovulation induction program.

The ultra-long regimen is to use long-acting gonadotropin-releasing hormone (GNRH) for one to several months before ovulation induction**, and only start ovulation induction after the indicators meet the criteria for ovulation induction, and the stimulation process is similar to that of the long regimen. Because the pre-descent adjustment is longer than the traditional long-term regimen, it is called the ultra-long regimen.

The ultra-long regimen is suitable for patients with endometriosis, polycystic ovary syndrome, and hyperrhopsemia, which can not only improve the hormone level and pelvic environment of patients, but also have a good conditioning effect on the endometrium.

The IVF long program and the IVF ultra-long program are distinguished by two points and can be divided into two points for discussion:

1. The IVF ultra-long program is relative to the long program, which is suitable for patients with endometriosis, polycystic ovaries, and hyperlhemia, because before IVF ovulation induction, the body of the IVF expectant mother must be hormonally regulated, and the IVF cycle is relatively long, so it is called the IVF ultra-long program.

2. The long program of IVF refers to the IVF patients with good ovarian reserve eggs, the previous cycle of IVF ovulation induction for people with regular menstruation, the 10th day of menstruation begins to monitor the development of IVF follicles until the day of ovulation of IVF, and the IVF expectant mother begins to perform IVF downgrading one week after ovulation, and after the next IVF menstruation, IVF ovulation induction begins until the middle of IVF menstruation.

When preparing for IVF pregnancy, it is recommended that expectant mothers relax and unwind, which will help improve the ovarian environment. There is no good or bad solution, only suitable and inappropriate, and the long plan is the most commonly used plan.

Difference Between Long and Ultra Long Plans:

The long program is the most commonly used program in IVF, suitable for young women, good ovarian function, its ovulation induction effect is good, the ultra-long program is generally suitable for patients with adenomyosis and endometriosis, its purpose is to play a certain role in inhibiting the reproductive endocrine system and increase the sensitivity of later medication.

Compared with the ultra-long regimen and the long regimen, only the amount of the previous medication is different, and the time is slightly longer, in addition to the other processes are basically the same, in fact, which plan the patient uses to promote the ovulation, which is mainly measured according to the difference in women's physique and the condition **.

The long program is the most commonly used program in IVF, suitable for young women, good ovarian function, its ovulation induction effect is good, the ultra-long program is generally suitable for patients with adenomyosis and endometriosis, its purpose is to play a certain role in inhibiting the reproductive endocrine system and increase the sensitivity of later medication.

Compared with the ultra-long regimen and the long regimen, only the amount of the previous medication is different, and the time is slightly longer, in addition to the other processes are basically the same, in fact, which plan the patient uses to promote the ovulation, which is mainly measured according to the difference in women's physique and the condition **.

The long plan and the short plan refer to the two types of test tubes, respectively, and different plans need to be adopted according to different systems.

Long regimen: The long regimen is one of the most commonly used ovulation induction regimens, mainly used in patients who are in a good general condition, have normal ovarian function, and can respond appropriately to stimulation medications.

Short regimen: Short regimen is primarily indicated for patients who are older, have a reduced ovarian reserve, or have a poor response to longer regimens. As the name suggests, the short plan takes a shorter period of time, which is basically similar to the menstrual cycle, and takes about 10-15 days before and after;

1. What plan needs to be used is not determined by time, but by the patient's ovarian function. In general, long regimens are used for good ovarian function, and short regimens are used for poor ovarian function.

2. Although the long plan has a long time, it has a good ovulation induction effect, good ovarian response, and better medication to control the growth of follicles, and generally does not cause early ovulation.

3. Although the short program is short, the ovulation induction effect is not good, the ovarian response is inconsistent and unstable, sometimes a large follicle may appear, and the growth of other follicles is inhibited, and finally only one follicle grows, and ovulation induction fails. Sometimes there is also the problem of early ovulation.

4. Therefore, the long plan is our conventional plan for ovulation induction, and the short plan is a backup plan for considering the patient's poor ovarian function and worrying that the long plan will not be able to promote the follicle.

5. Doing IVF and ovulation induction is to obtain more eggs and increase the success rate. It's not about being in a hurry. After all, the couple who did the IVF must have not been pregnant for many years, so they are not in a hurry at this time. It is not wise to lose more follicles in order to catch up.

6. Before the start of the short program, it is sometimes necessary to use other drugs in advance, so the time is not necessarily short.

IVF long program: Different women have different conditions, and the cycle in the long program process is also different. In general, long-term regimens are usually started on the 21st day of the previous menstrual period with a gonadal hormone-releasing hormone agonist (GNRHA).

On the 10th day of GNRHA use, ovulation induction drugs were used, and then B-ultrasound was performed regularly to monitor the growth of follicles, and blood was drawn to measure estrogen content, and the dosage and cycle of stimulation drugs were adjusted according to the monitoring results. Indications for the long regimen of IVF: women who are younger and have good ovarian reserve.

Advantages of long program: Although the long program has a long time, it has a good effect on stimulation, good ovarian response, medication can control the growth of follicles, and there will generally be no early ovulation, which effectively increases the success rate.

IVF short program: generally start to inject dufferin on the 2nd to 3rd day of menstruation, inject follicle-stimulating hormone in the afternoon of the next day, and then perform ultrasound to monitor the growth of follicles from time to time, and draw blood to measure estrogen content. According to the monitoring results, the ovarian response to the drug is judged, and the dose of ovulation induction drugs is adjusted accordingly until the follicles are matured by ultrasound monitoring, and the eggs can be retrieved on the 3rd day of the HCG injection day about 8-12 days after the ovulation induction medication.

Advantages of short regimen: GN ovulation induction medication is small, short use time, simple and flexible.

To do IVF, we need to understand: what plan to use is not determined by time, but by the patient's ovarian function.

The functional grade is light and the basic long plan, on the contrary, the short case, but it is not absolute, the doctor will look at each person's physique and wait for the plan.

The long-term plan of contraceptive pills is suitable for people with good warm super function and the short plan is suitable for people who are not good.

Long regimen long regimen is mainly suitable for patients with good ovarian reserve, people with regular menstruation ovulation induction ** to the first 1 cycle of menstruation to monitor follicle development on the 10th day of menstruation until the date of ovulation is determined, 1 week after ovulation begins to use GNRH agonists for pituitary descending source regulation, after the next menstrual period begins to formally induce ovulation until about 100 menstrual mid-menstrual egg retrieval. People with irregular menstruation should start taking Mafulon on the 5th day of menstruation and start taking GNRH agonists on the 21st day of menstruation. This regimen can be used in patients with normal basic indicators of ovarian function.

Short square degree case. CNRHA is used on the second day of the menstrual cycle, and gonadotropins are given until the injection of HCG, which is mainly to take advantage of the rapid release effect of FSH and LH after the use of GNRHA to reduce the dosage and duration of exogenous gonadotropins. For patients with poor ovarian function and low egg count after using a long regimen, a short regimen is generally recommended.

The definition of long and short programs of IVF is introduced by Tai Dongfang as follows: long plan: start using GNRH-A on the 21st day of the previous menstrual cycle, start using stimulation drugs on the 10th day, and then monitor the development of follicles through B ultrasound from time to time, and draw blood to measure the level of sex hormones, adjust the dosage of ovulation induction drugs according to the results of the examination, until the follicles are mature, inject HCG in the evening to promote maturation, and eggs can be retrieved after 36 hours of HCG injection.

Short program: start to use GNRH-A on the 2nd day of the menstrual cycle to promote the secretion of FSH and LH, so as to strengthen the stimulation effect, the later stage of GNRHA use gradually turns to a down-regulating effect, start to use ovulation induction drugs on the 3rd day of menstruation, monitor the development of follicles through B ultrasound at any time, and draw blood to measure the level of sex hormones, adjust the dosage of ovulation induction drugs according to the examination results, until the follicles are mature, inject HCG in the evening to promote maturation, and eggs can be retrieved 36 hours after HCG injection.

First, the long plan.

Generally, doctors will recommend a long-term program for relatively young people, who are generally under the age of 30. People who choose the long regimen start using GNRHA at the end of the 3rd week of the menstrual cycle, and this period is also known as the mid-luteal period. Ovulation induction drugs are started only after a week and a half of GNRHA use, and follicular development is checked frequently by ultrasound.

At the same time, the estrogen level is also determined by blood testing. The doctor will inject 10,000 IU of HCG at the right time, and the eggs will be retrieved after a day and a half.

Second, the short program.

The short regimen is suitable for older women or women with poor ovarian function. Those who choose a short regimen can use GNRHA on the second day of their menstrual cycle, and within three days, the secretion of FSH and LH will gradually increase. As the follicles grow, the positive effect of GNRHA will become down-modulation, so on the 3rd day, you can take ovulation induction drugs to keep up.

In the future, there will usually be one or two ultrasound tests and blood tests for estrogen, and the dose and timing of the drug will be adjusted accordingly according to the ovarian response. After the eggs are matured, HCG is injected at night, which is shorter than the long plan, and the egg retrieval time is also 36 hours later.