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First, the composition is different.
1. Adenosylcobalamin tablets: the main ingredient is adenosylcobalamin.
2. Vitamin B12: Vitamin B12 is a polycyclic compound containing 3-valent cobalt, and 4 reduced pyrrole rings are connected together to become 1 granolino-macroring (similar to porphyrin), which is the core of the vitamin B12 molecule.
Second, the physiological role is different.
1. Adenosylcobalamin tablets: It is a homogeny of cyanocobalamin-type vitamin B12, that is, its CN base is replaced by adenine nucleoside to become 5'- Deoxyadenosylcobalamin, one of the two active coenzyme forms of vitamin B12 in the body, is necessary for cell growth and proliferation and the maintenance of the integrity of the nerve myelin.
2. Vitamin B12: promote methyl transfer; Promote the development and maturation of red blood cells, make the body's hematopoietic function in a normal state, and prevent pernicious anemia; Maintain nervous system health; In the form of coenzymes, it can increase the utilization of folic acid and promote the metabolism of carbohydrates, fats and proteins.
Third, the traits are different.
1. Adenosylcobalamin tablets: This product is a sugar-coated tablet, which is pink after removing the sugar-coating.
2. Vitamin B12: Vitamin B12 is a light red needle-like crystal, soluble in water and ethanol.
Encyclopedia - Adenosylcobalamin tablets.
Encyclopedia - Vitamin B12
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1. The ingredients are different.
Adenosylcobalamin tablets: The main ingredient is adenosylcobalamin.
Vitamin B12
A polycyclic compound containing 3-valent cobalt, 4 reduced pyrrole rings linked together to form a single cogliline macroring (similar to porphyrin), which is the core of the vitamin B12 molecule.
2. Different traits.
Adenosylcobalamin tablets: It is a sugar-coated tablet, which appears pink after the sugar-coating is removed.
Vitamin B12: Vitamin B12 is a light red needle-like crystal that is easily soluble in water and ethanol.
at pH. It is the most stable under weak acid conditions, decomposed in strong acid (pH<2) or alkaline solution, and can be damaged to a certain extent when heated, but the loss of high-temperature disinfection in a short period of time is small, and it is exposed to strong light or ultraviolet rays.
Easily destroyed. <>
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Vitamin B12 is a general term for vitamin B group chemicals that have a cobalt-line ring structure. Because cyanocobalamin was first discovered as a vitamin that the human body relied on for survival, and it was water-soluble, there were 12 in order at that time, so cyanocobalamin was called vitamin B12. Later, with the deepening of people's understanding, I learned that this kind of substance can maintain this kind of life activity is not the only one, and it was also discovered that cyanocobalamin, which was first called vitamin B12, cannot directly participate in biochemical reactions in the human body!
There are four types of vitamin B12 that are commonly used today: methylcobalamin, adenosylcobalamin, hydroxocobalamin, and cyanocobalamin. The first two of them can directly participate in a variety of biochemical reactions in the human body, so they are called coenzyme vitamin B12; In order to participate in life activities, the latter two must first be transformed into the first two forms in the cell before they can function.
Based on the above instructions, you know the relationship between adenosylcobalamin and vitamin B12.
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Methylcobalamin: Methylcobalamin is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction of methionine synthesis from homocysteine. In vitro studies have shown that methylcobalamin promotes lecithin synthesis and neuronal myelination in cultured rat tissues for peripheral neuropathy.
Vitamin B12
Vitamin B12, also known as cobalamin, is the only vitamin that contains metallic elements. Vitamin B12 in nature is synthesized by microorganisms, and higher animals and plants cannot make vitamin B12. Vitamin B12 is the only vitamin that needs the help of an intestinal secretion (endogenous factor) to be absorbed.
Some people lack this endogenous factor due to gastrointestinal abnormalities, and even if the diet is sufficient, they will suffer from pernicious anemia. Vitamin B12 is largely absent from plant foods. It stays in the intestine for a long time, taking about three hours (most water-soluble vitamins only take a few seconds) to be absorbed.
The main physiological function of vitamin B12 is to participate in the production of bone marrow red blood cells and prevent pernicious anemia; Prevents damage to the nerves of the brain. Vitamin B12 is the latest of the B vitamins to be discovered so far. Vitamin B12 is a polycyclic compound containing 3-valent cobalt, and 4 reduced pyrrole rings are linked together to form a large cyclic (similar to porphyrin), which is the core of the vitamin B12 molecule.
Therefore, compounds containing such rings are called gogolines. Vitamin B12 is a light red needle-like crystal, soluble in water and ethanol, the most stable under the condition of weak acid at pH value, decomposed in strong acid (pH<2) or alkaline solution, it can be damaged to a certain extent when heated, but the loss of high-temperature disinfection in a short period of time is small, and it is easy to be destroyed in case of strong light or ultraviolet rays. About 30% of the loss is lost in the ordinary cooking process.
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Methylcobalamin is an endogenous coenzyme B12 found in the blood and medullary fluid. Compared with vitamin B12, it has a good effect on the conduction of neurons!
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In fact, methylcobalamin is a type of vitamin B12. Because cyanocobalamin was first discovered, cyanocobalamin is generally considered to be vitamin B12Now I finally figured out that vitamin B12 comes in many forms, and methylcobalamin is one of them.
There are many types of vitamin B12, but there are only two types that can be directly used by the body, one is methylcobalamin and the other is adenosylcobalamin. However, methylcobalamin is directly involved in methyl transmission between human nerve tissues and can effectively repair damaged nerves, so methylcobalamin is used as a drug for peripheral neuropathy.
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Vitamin B12, also known as cyanocobalamin, is an important coenzyme for the synthesis of nucleotides in cells and is involved in folate metabolism. Methylcobalamin (currently used in China) is an endogenous coenzyme B12 that is more easily transferred to the organelles of nerve cells than cyanocobalamin and promotes the synthesis of nucleic acids and proteins. The mechanism of action of the two is similar, and it is mainly used for peripheral neuropathy and macrocytic anemia caused by vitamin B12 insufficiency.
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Methylcobalamin is adenoglycine B12, and the composition of the two is different, and the effect is different.
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Methylcobalamin is mainly used for megaloblastic anemia, dystrophic anemia, anemia during pregnancy, polyneuritis, radiculitis, trigeminal neuralgia, sciatic. Nerve palsy can also be used as an adjunct to nutritional disorders and radiation- and drug-induced leukopenia**.
Vitamin B12 is mainly used for pernicious anemia; Combined with folic acid** other megaloblastic anemia, anemia and steatorrhea caused by antifolic acid drugs; It is also used for certain neurological diseases such as neuritis, nerve atrophy, liver diseases such as liver cirrhosis, hepatitis, etc., as well as blood diseases such as leukopenia, aplastic anemia, etc. Vitamin B12 is the least required in the human body every day, and excessive amounts of vitamin B12 can be toxic. Excessive vitamin B12 injections have been reported to cause allergic reactions such as asthma, urticaria, eczema, facial puffiness, and chills, as well as nerve excitation, precordial pain, and palpitations.
Excessive intake of vitamin B12 can also lead to folate deficiency.
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Unlike methylcobalamin, methylcobalamin is methylated VB12, and ordinary VB12 is inactive. If it is used as a nerve repair agent, methylcobalamin is recommended!
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Methylcobalamin tablets are white sugar-coated tablets, after removing the sugar-coating, they appear pink e68a8462616964757a686964616f31333431353338, the main ingredient is methylcobalamin, methylcobalamin is an endogenous coenzyme B12, also known as vitamin B12, which participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction process of methionine synthesis from homocysteine. In vitro studies have shown that methylcobalamin can promote the synthesis of lecithin and the formation of myelin in neurons in cultured rat tissues, which is suitable for peripheral neuropathy, various neuritis neuralgia, autonomic neurological disorders, and more. The preparation of methylcobalamin is methylcobalamin tablets.
Methylcobalamin is a methylated vitamin B12 that belongs to the vitamin B12 family and has a different chemical structure from the other three vitamin B12s. Mainly used for **peripheral neuropathy. Methylcobalamin tablets are different from vitamin B12, methylcobalamin tablets are derivatives of vitamin B12, which is a kind of coenzyme B12, focusing on coenzyme, which is an enzyme that is easier to enter the nerve than B12 and has good transmission to nerve tissue in order to play a role.
Methylcobalamin tablets are also called methylcobalamin, methylcobalamin generally refers to domestic production, and Micobao (methylcobalamin tablets) is imported, but it cannot be eaten for a long time. Just as an adjunct, put vitamin B12 in the long-term do not eat, although Micobo (methylcobalamin tablets) and B12 are related, but the usage is different, ** the disease is also different for the point.
The role of vitamin B group and methylcobalamin tablets is not the same, the former is used as an aid to your indigestion, nausea, headache**, the latter is to repair the nutritional nerves, and it is not contradictory to eat at the same time. Methylcobalamin tablets***: 1
Allergies occasionally cause rashes (incidence <), please stop taking the drug after the appearance of allergies. 2.Others occasionally (incidence 5% loss of appetite, nausea, vomiting, diarrhea.
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Summary. Hello, yes, taking methylcobalamin tablets can cause high serum vitamin B12, because methylcobalamin is a source of coenzyme B12. Some studies have found that after taking methylcobalamin tablets for one month, the vitamin B12 content in some patients will exceed the normal value by nearly two times, which can easily cause vitamin B12 poisoning, diarrhea, nausea and other symptoms.
Therefore, taking methylcobalamin tablets can cause serum vitamin B12**.
Hello, yes, taking methylcobalamin tablets can cause high serum vitamin B12, because methylcobalamin is a source of coenzyme B12. Some studies have found that after taking methylcobalamin tablets for one month, the vitamin B12 content in some patients will exceed the normal value by nearly two times, which can easily cause vitamin B12 poisoning, diarrhea, nausea and other symptoms. Therefore, taking methylcobalamin tablets can cause serum vitamin B12**.
Methylcobalamin tablets are a drug that nourishes nerves and has good transmission to nerve tissue. Methylcobalamin tablets can generally effectively promote the recovery of nerve function after medication, and are mostly used for some peripheral nerve damage and other diseases, such as neuritis, nerve pain or diabetes, poor blood sugar control, cervical spondylosis, etc.
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Vitamin B12, also known as cobalamin, is the only vitamin that contains metallic elements. Vitamin B12 in nature is synthesized by microorganisms, and higher animals and plants cannot make vitamin B12.
Adenosylcobalamin is a homogenant of cyanocobalamin-type vitamin B12, i.e. its CN group is replaced by adenine nucleoside to become 5'- Deoxyadenosylcobalamin, which is one of the two active forms of coenzyme vitamin B12 in the body, is necessary for cell growth and reproduction and the maintenance of the integrity of the myelin sheath of the nervous system.
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What is the role of adenosine vitamin B12.
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1. The ingredients are different.
Adenosylcobalamin tablets: The main ingredient is adenosylcobalamin.
Vitamin B12: A polycyclic compound containing 3-valent cobalt, 4 reduced pyrrole rings linked together to form 1 cooline macroring (similar to porphyrins), which is the core of the vitamin B12 molecule.
2. Different traits.
Adenosylcobalamin tablets: It is a sugar-coated tablet, which appears pink after the sugar-coating is removed.
Vitamin B12: Vitamin B12 is a light red needle-like crystal, soluble in water and ethanol, the most stable under the condition of weak acid at pH value, decomposed in strong acid (pH<2) or alkaline silver calendar solution, it can be damaged to a certain extent when heated, but the loss of high-temperature disinfection in a short period of time is small, and it is easy to be destroyed in case of strong light or ultraviolet rays.
Expand the surplus material of the resource
Vitamin B12 main function.
1. Promote methyl transfer.
2. Promote the development and maturation of red blood cells, make the body hematopoietic function in a normal state, and prevent pernicious anemia; Maintain nervous system health;
3. In the form of coenzyme, it can increase the utilization rate of folic acid and promote the metabolism of carbohydrates, fats and proteins.
4. It has the effect of activating amino acids and promoting the biosynthesis of nucleic acids, which can promote the synthesis of proteins, and it plays an important role in the growth and development of infants and young children.
5. Metabolize fatty acids, so that fats, carbohydrates and proteins can be properly used by the body.
6. Eliminate irritability, concentrate attention, enhance memory and sense of balance.
7. It is an indispensable vitamin for the sound function of the nervous system, and participates in the formation of a lipoprotein in nerve tissue.
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